The Boston Red Sox will look to make it two in a row as they continue their road series against the Detroit Tigers on Tuesday night.
Framber Valdez takes the mound for Detroit, and I’m counting on him to give his team the edge in my Red Sox vs. Tigers predictions below.
Read on to see my full analysis and get my free MLB picks for Tuesday, May 5.
Who will win Red Sox vs Tigers today: Tigers -1.5 (+137)
The Detroit Tigers are struggling with injuries to their pitching staff, but they still have a healthy Framber Valdez to take the mound tonight.
Valdez is a solid 2-1 with a 3.35 ERA so far in his first season in Detroit, and the Tigers are 5-2 in his starts this season.
The Boston Red Sox will use open Jovani Moran tonight. And while that’s fine on the surface, the fact that Brayan Bello (1-4, 9.12 ERA) will try to pick up the bulk of the innings is concerning given his struggles so far this season.
With a massive advantage on the mound at home, I’m taking Detroit to cover the run line.
COVERS INTEL: The Red Sox are fifth in the majors in batted ground ball percentage at 45.7%, which should play into the hands of Valdez, who has averaged a 61.2% ground ball rate in his career.
Red Sox vs Tigers Over/Under pick: Under 8.5 (-115)
The Red Sox have struggled to score runs all season long. At 3.86 runs per game, Boston is one of just five teams in the majors averaging less than four runs per contest, and its .671 OPS ranks 27th in the league.
If Valdez can handle his business against the Red Sox, it will come down to Detroit to carry this total. But the Tigers have averaged only 4.28 runs per game over their last seven games, so it’s far from certain they’ll put up huge numbers tonight either.
The total of 8.5 runs is close to correct, but given reason trends, the Under is my play.
- ML/RL bets: 5-10, -5.31 units
- Over/Under bets: 5-8, -3.43 units
Red Sox vs Tigers odds
- Moneyline: Boston +140 | Detroit -155
- Run line: Boston +1.5 (148) | Detroit -1.5 (+134)
- Over/Under: Over 8.5 (+105) | Under 8.5 (-116)
Red Sox vs Tigers trend
The Tigers are 4-1 overall in Valdez’s last five starts. Find more MLB betting trends for Red Sox vs. Tigers.
How to watch Red Sox vs Tigers and game info
| Location | Comerica Park, Detroit, MI |
| Date | Tuesday, May 5, 2026 |
| First pitch | 6:40 p.m. ET |
| TV | NESN, DSN |
| Red Sox starting pitcher | Brayan Bello (1-4, 9.12 ERA) |
| Tigers starting pitcher | Framber Valdez (2-1, 3.35 ERA) |
Red Sox vs Tigers latest injuries
Red Sox vs Tigers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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