The Los Angeles Dodgers are a win away from punching their ticket to the World Series for a second consecutive fall, and they host the Milwaukee Brewers at Dodger Stadium on Friday, October 17.
Milwaukee hasn’t had an answer for the Los Angeles pitching staff, and my Brewers vs. Dodgers predictions and MLB picks expect The Boys in Blue to be celebrating a convincing sweep following Game 4 tonight.
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Brewers vs Dodgers Game 4 predictions
Who will win Brewers vs Dodgers Game 4
The Dodgers have superstar Shohei Ohtani starting, while the Brewers are expected to lean on veteran lefty Jose Quintana for big innings Friday.
There’s been no comparison between the two lineups through three games, and this pitching matchup projects for more of the same in the NLCS.
Brewers vs Dodgers best bet: Dodgers -1.5 run line (+110)
Let’s face it.
It took an all-world outing from Milwaukee Brewers rookie Jacob Misiorowski in bulk relief to keep Game 3 close, and I’m not expecting lefty Jose Quintana and the Milwaukee bullpen to have the same success tonight.
The Los Angeles Dodgers have received elite pitching through the first three games of the series, and righty Shohei Ohtani has been nothing short of spectacular since returning to the mound in June and stretching down over the summer.
Ohtani finished the regular season with a 2.87 ERA, 1.04 WHIP, and 2.45 xFIP across 47 innings, and he was even better at home with respective 1.71, 0.71, and 2.17 marks.
Of course, he also fanned nine across six frames in winning fashion against a much tougher Philadelphia Phillies lineup in the NLDS.
Even better, the Milwaukee lineup will largely be facing Ohtani for the first time, with Andrew Vaughn, Danny Jansen, and Jake Bauers combining for 10 career plate appearances against the righty.
The Dodgers' lineup has also been a consistent presence this postseason with a second-ranked wOBA and fourth-ranked ISO, while Milwaukee checks in with seventh overall marks in both.
Of course, Los Angeles also finished the regular season with a third-ranked wOBA and second-ranked ISO against southpaws, and respective second and first overall ranks at Dodger Stadium.
The Blues in Boy convincingly punch their World Series ticket tonight.
Brewers vs Dodgers Game 4 same-game parlay (SGP)
As good as the Los Angeles rotation has been, Milwaukee is sporting a .137 BABIP despite a respectable 43.3% hard-hit rate. Those two extremes are brutal to sustain. If there’s a splash of statistical correction in the Brewers' favor, the loaded Dodgers lineup will do the heavy lifting for this Over.
Los Angeles star Mookie Betts has had his fair share of tough luck in the NLCS, too. While he’s teed off for a solid 44.4% hard-hit rate, the three-time World Series champion has gone just 1-for-11 at the dish with a .111 BABIP.
I’m expecting the slump to end tonight for Betts. He went 10-for-26 with three extra base hits and a .429 wOBA across six games to start the playoffs, after all.
Brewers vs Dodgers SGP
- Los Angeles Dodgers -1.5 run line
- Over 8
- Mookie Betts Over 1.5 total bases
Brewers vs Dodgers home run pick for Game 4
Sticking with Betts, he posted a monster .238 ISO with 29 home runs against lefties from 2022 through last year, so dropping to a .164 mark with just seven round trippers during the 2025 regular season is another call for positive regression to answer tonight.
Brewers vs Dodgers Game 4 odds
- Moneyline: Milwaukee +165 | Los Angeles -200
- Run line: Milwaukee +1.5 (-130) | Los Angeles +110
- Over/Under: Over 7.5 (-120) | Under 7.5 (+100)
Brewers vs Dodgers trend
The Los Angeles Dodgers have covered the run line in 19 of their last 29 games (+11.65 Units / 33% ROI). Find more MLB betting trends for Brewers vs. Dodgers.
How to watch Brewers vs Dodgers and Game 4 info
| Location | Dodger Stadium, Los Angeles, CA |
| Date | Friday, October 17, 2025 |
| First pitch | 8:38 p.m. ET |
| TV | TBS |
| Brewers starting pitcher | TBA (X-X, X.XX ERA) |
| Dodgers starting pitcher | Shohei Ohtani (1-1, 2.87 ERA) |
Brewers vs Dodgers latest injuries
Brewers vs Dodgers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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