Jaguars @ 49ers Game Overview

Starter Brock Purdy was sidelined the last two games with turf toe, but Mac Jones has taken the reins, leading the 49ers to wins over New Orleans and Arizona.

Now, it's looking like a role reversal for Sunday's game against the Jacksonville Jaguars in Santa Clara, Calif.

Purdy (left shoulder/toe) has been announced as the starter for Sunday, while Jones (knee) has been limited in practice all week and his availability is questionable, though Jones has said that he, too, will be ready to go.

"(Purdy) looked good," 49ers coach Kyle Shanahan told reporters while confirming Purdy would start. "He got to do a lot more than last week and each day he got a lot better."

Adrian Martinez, 25, signed with the 49ers (3-0) in August after being waived by the New York Jets. He was promoted from the practice squad to serve as the backup last week with Purdy inactive and has never appeared in an NFL regular-season game. He can back up Purdy if Jones is unavailable.

The injury news is mixed elsewhere. Defensive lineman CJ West (thumb) and wideout Jordan Watkins (calf) were ruled out of the contest. Receivers Jauan Jennings (ankle/shoulder) and Ricky Pearsall (knee) are questionable, as are guard Connor Colby (groin) and cornerback Renardo Green (neck).

The Jaguars (2-1) are coming off their first home win over Houston since 2017. Now, they seek their first win in San Francisco. They've lost both trips there and the last five games in the series.

For the second time in three games, Jacksonville's defense didn't allow a touchdown until the fourth quarter of last week's 17-10 win over the Texans. The Jags are tied for fifth in scoring defense (17.0 points per game), 10th in total defense (292.0 yards per game) and lead the league with nine forced turnovers, as many as they had all of last season, which was last in the NFL.

Jacksonville rookie Travis Hunter has played a greater role in that success over the last two weeks. After playing largely on offense in Week 1, the No. 2 overall pick has been a true two-way player the last two weeks, playing at least 37 snaps on both offense and defense in each game.

He enters Sunday's game with 10 catches for 76 yards on offense and nine tackles with one pass breakup on defense. He had six tackles (one off the team lead) and a shifty 21-yard catch in the Houston win.

To keep things as simple as possible, Jacksonville is limiting Hunter to a specific position on each side of the ball as a rookie.

"We had a great talk with Trav after this past game in terms of just, ‘How can we help you 1/2' Because what is he learning 1/2 It's a lot," Jaguars head coach Liam Coen said. "We've got to, I think, be a little more diligent in terms of putting him in positions to maybe not have to do as many moving parts so that we can let him go play."

The San Francisco defense took a hit Sunday when five-time Pro Bowl edge rusher Nick Bosa sustained a season-ending knee injury. Losing a player who had nine-plus sacks each of the last four seasons will hinder a defense that ranks third in scoring defense (16.3) and fourth in total defense (265.7).

It puts an onus on players like rookie first-round pick Mykel Williams and veteran defensive end Bryce Huff (22 career sacks), whom the 49ers traded for in June, to rise to the challenge.

"We're calling on a lot of guys who probably didn't know that they were going to be needed as much as they have been," 49ers linebacker Fred Warner said.

Additionally, for San Francisco, defensive end Yetur Gross-Matos (knee) missed two practices this week, including Friday's.

Jaguars guard Wyatt Milum (knee) has been ruled out. Wide receiver Dyami Brown (shoulder) and linebacker Yasir Abdullah (hamstring) were limited on Friday and are questionable.

--Field Level Media