Dak Prescott Picks, Predictions & Best Bets for Monday Night Football

Dak Prescott will pick up completions galore vs. the Cardinals on MNF, per our NFL betting picks.

Jeremy Jones - Contributor at Covers
Jeremy Jones • Betting Analyst
Nov 2, 2025 • 16:12 ET • 4 min read
 Dallas Cowboys NFL Dak Prescott
Photo By - Imagn Images. Dallas Cowboys quarterback Dak Prescott (4) looks to throw.

Dak Prescott and the 3-4-1 Dallas Cowboys will play host to the 2-5 Arizona Cardinals, who are again without Kyler Murray, on Monday Night Football. 

Prescott has put up MVP-type numbers, but his defense has not given him the help to give the Cowboys a better record.

Let's take a look at the Dak Prescott odds for Monday, November 3, and don't miss Josh Inglis' Cardinals vs. Cowboys predictions!

Dak Prescott prop pick

Dak Prescott best bet: Over 25.5 pass completions (-110 at bet365)

Dak Prescott has 2,069 passing yards and 16 touchdowns to only five interceptions through eight games. He also has a QBR of 79.5, which would be a career-best in a single season for him. 

Prescott also has a career best 70.3% completion percentage this season. He isn’t trying to force things in the deep passing game, and is instead taking what the defense is giving him. That is why I love taking his completions in this matchup rather than just taking his yardage prop. 

The Arizona Cardinals have allowed only 9.3 yards per attempt, which is seventh-fewest in the NFL, to opponents throwing downfield. However, they rank 25th in the NFL in total passing yards allowed, which means they give up a ton of quick passes. 

The Cardinals have played Cover 4 at the highest rate in the NFL this season, deploying the coverage scheme on 32.3% of dropbacks. Prescott has completed 74.3% of his passes and averaged 8.6 yards per attempt against Cover 4 this season.

With this matchup, Prescott will be more than happy to throw it underneath to guys like CeeDee Lamb and Jake Ferguson, with the occasional big play shot to George Pickens. 

Dak Prescott same-game parlay

Dak Prescott Over 25.5 pass completions

Marvin Harrison Jr. Over 59.5 receiving yards

Trey McBride anytime TD

Marvin Harrison Jr. has recorded 55+ receiving yards in three of his last four games. He'll beat up on a soft Dallas Cowboys defense, forcing Dak to keep throwing on MNF.

Finally, I'm adding Trey McBride to find the end zone, as he has been a heavy red-zone target for Jacoby Brissett with three touchdowns in the last two games for the Cardinals.

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Jeremy Jones - Covers
Betting Analyst

Jeremy Jones was born and raised in Lexington, Kentucky and has been a massive Wildcats fans since the moment he came into the world. He wrote his first sports article at the tender age of 11 after attending a local AHL hockey game, and a few years later was writing professionally for sites such as Sports Rants, BetAmerica, and TwinSpires.

Jeremy holds a Masters in Sports Administration from Eastern Kentucky University and utilizes all seven betting options available in Kentucky to shop for odds and promos and find the greatest EV in every wager he places.

His best piece of sports betting advice is to stick to consistent unit sizes for every wager. He acknowledges there will occasionally be a bet that has a huge EV and you can play multiple units in one bet, but cautions against raising your unit size, because you can quickly lose all your winnings if you hit a minor cold streak.

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