North Carolina vs Syracuse Prediction, Picks & Odds for October 31 — College Football Week 10

Much has been made about North Carolina's improved play of late, but have they actually won a game this month? No? Well, despite Syracuse's own struggles, the Orange will win and pop the Bill Belichick balloon even further.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Oct 30, 2025 • 10:15 ET • 4 min read

NCAAF

Match starts: 27 hrs
SYR
61 %
UNC
39 %
EXPERT PICK - SPREAD
Syracuse -2.5 (-106) Syracuse -2.5 (-106)
Read Analysis
Johntay Cook Syracuse Orange NCAA College Football
Photo By - Imagn Images. Syracuse WR Johntay Cook makes a sideline catch.

Losing their starting quarterback has derailed the Syracuse Orange’s season. While they’ve looked bad since, it's not burn the program to the ground with a former NFL legend with a 24-year-old girlfriend bad.

That’s exactly what the Orange are up against when they host Bill Belichick and the North Carolina Tar Heels at the JMA Wireless Dome. Oddsmakers have been impressed with the Tar Heels lately, making them just 2.5-point dogs in this matchup.

But my North Carolina vs. Syracuse predictions aren’t buying it, and my college football picks are backing the team with the head coach who actually knows the college game on Friday, October 31.

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North Carolina vs Syracuse prediction

North Carolina vs Syracuse best bet: Syracuse -2.5 (-106)

Some will say that Bill Belichick’s North Carolina Tar Heels have shown some fight in the last couple of games. But let’s not go crazy just yet.

Belichick’s squad is on a four-game losing streak, still searching for its first win over a Power 4 team this season. But close losses at Cal and a near-upset of Virginia last week have some wondering if the Tar Heels are starting to buy what Belichick is selling.

However, this team is still plagued with problems, the biggest of which is the offense. The Tar Heels haven’t put QB Gio Lopez in the best position to succeed and, as a result, North Carolina ranks 127th in EPA per play and 124th in offensive success rate. 

They have averaged just 13.4 points per game vs. Power 4 opponents and haven’t scored more than 18 points in those five matchups.

Yes, the Syracuse Orange have struggled since starting QB Steve Angeli went down with an ankle injury, losing four in a row since the win over Clemson. Now, I’ll give them a little leeway because they have played four of the top teams in the conference over that stretch.

But the one thing I can’t get past in this game is the coaching matchup.

One team has a guy who is trying to build something at a traditional basketball school. The other has Bill Belichick.

Yes, the Tar Heels have shown some fight recently, but I have more confidence in Fran Brown to have his team prepared for this matchup. Expect him to try someone new at QB this week, as well. The JMA Wireless Dome should be rocking, and I like the better-coached team to win and cover this ACC matchup.

North Carolina vs Syracuse same-game parlay

Wide receivers go wild in this SGP.

Whoever is throwing the football for Syracuse should lean on Johntay Cook. The Orange wideout has been impressive all season long, hauling in 37 catches for 456 yards and two touchdowns. But the impressive thing is he's continued that play even when Angeli got hurt, catching 21 of 29 targets for 267 yards over the last four games. 

North Carolina ranks 112th in EPA per dropback this season, so Cook will (sorry) cook in this one. He'll go Over his reasonable receiving prop of 54.5 for the fourth time in five games.

But he won't be the only wideout to shine here. UNC's Jordan Shipp has been one of the few bright spots on this Tar Heels offense. He’s got 22 catches for 253 yards and two scores this season, and he gets a solid matchup against a Syracuse secondary that ranks 90th in EPA per dropback.

North Carolina vs Syracuse SGP

  • Syracuse -2.5
  • Johntay Cook Over 54.5 receiving yards
  • Jordan Shipley Over 50.5 receiving yards

Our deep-ball SGP: Under Pressure

Just because a couple of wideouts could rack up some yards, it doesn't mean they're going to find the end zone. And it's not like these are huge numbers. These offenses have struggled, and that will continue. 

North Carolina vs Syracuse SGP

  • Syracuse -2.5
  • Johntay Cook Over 54.5 receiving yards
  • Jordan Shipley Over 50.5 receiving yards
  • Under 45.5

North Carolina vs Syracuse odds

  • Spread: North Carolina +2.5 | Syracuse -2.5
  • Moneyline: North Carolina +112 | Syracuse -132
  • Over/Under: Over 45.5 | Under 45.5

North Carolina vs Syracuse trend to know

The Under is 5-1 in North Carolina's last six games overall and 3-1 in Syracuse's last four. Find more college football betting trends for North Carolina vs Syracuse.

How to watch North Carolina vs Syracuse

Location JMA Wireless Dome, Syracuse, NY
Date Friday, October 31, 2025
Kickoff 7:30 p.m. ET
TV ESPN

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.

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