Mississippi vs NC State Prediction, Picks & Odds for Today's College Basketball Game

NC State can score with the best of them, and its offense will overwhelm the Rebels this afternoon.

Eric Rosales - Contributor at Covers.com
Eric Rosales • Betting Analyst
Dec 21, 2025 • 09:07 ET • 4 min read

NCAAB

Match starts: 2 hrs
NCST
60 %
MISS
40 %
EXPERT PICK - SPREAD
NC State -6.5 (-110) NC State -6.5 (-110)
Read Analysis
NC State Wolfpack guard Quadir Copeland (11) dribbles down the court during the first half of the game against UNC Asheville Bulldogs at Lenovo Center.
Photo By - Imagn Images. NC State Wolfpack guard Quadir Copeland (11) dribbles down the court during the first half of the game against UNC Asheville Bulldogs at Lenovo Center.

The NC State Wolfpack look for their fourth win in the last five games when they battle the Mississippi Rebels this afternoon from First Horizon Coliseum in Greensboro, NC.

It’s the Rebels’ third straight game played at a neutral site, and my Mississippi vs NC State predictions believe the Wolfpack will overwhelm their opponents on offense.

Find out why in my college basketball picks for December 21.

Mississippi vs NC State prediction

Mississippi vs NC State best bet: NC State -6.5 (-110)

Offense hasn’t been a problem for the NC State Wolfpack, scoring 89.3 points per game on 49% shooting from the field and 38.9% from 3-point range — both Top 4 marks in the ACC.

That’s helped outscore the problems the defense has faced, with NC State ranking a distant 16th in the conference in points allowed.

It’s an entirely flipped concept for the opponent, as Mississippi is the lowest scoring team in the SEC, putting up just 75.4 ppg. On the other end of the court, though, the Rebels are a Top 3 defense in the conference, allowing just 67.7 ppg.

Those scoring splits explain why Mississippi is one of the streakier teams in the SEC and why it's working to be a more consistent side.

The Rebels started the year with a 5-0 run, then dropped the next four — where they averaged just 66.8 ppg — before snapping out of that with back-to-back wins.

That lack of scoring has been a big reason why the Rebels are just 1-8-0 against the spread over their last nine games. 

What's more concerning is that's with a schedule ranked 206th in KenPom’s strength of schedule metric. The Wolfpack’s level of competition is a level up — ranking 67th overall — and they’ve covered the spread in three of their last four outings.

NC State should find enough offense this afternoon to cover the spread again.

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Mississippi vs NC State same-game parlay

NC State leading scorer Darrion Williams missed the last game against Texas Southern, but in his last outing, he went for 17 in the loss to Kansas.

However, that’s just the second time in Williams’ last seven games he’s scored 16 or more. The Ole Miss defense isn’t exactly a team that allows you to get right, either.

Quadir Copeland leads NC State in assists at 5.5 per game, but that total has been upped of late. He had nine dimes against Texas Southern and has tallied at least six assists in five of his last six games.

Mississippi vs NC State SGP

  • NC State -6.5
  • Darrion Williams Under 15.5 points
  • Quadir Copeland Over 5.5 assists

Our beyond the arc SGP: Wolfpack howling

Ven-Allen Lubin is the Wolfpack's top rebounder, grabbing at least nine boards in six of his last nine games. Mississippi ranks outside the SEC's Top 10 in rebounding.

NC State has gone Over the total in back-to-back games, and this might be the best offense the Rebels have seen yet this season.

Mississippi vs NC State SGP

  • NC State -6.5
  • Darrion Williams Under 15.5 points
  • Quadir Copeland Over 5.5 assists
  • Ven-Allen Lubin Over 7.5 rebounds
  • Over 145.5

Mississippi vs NC State odds

  • Spread: Mississippi +6.5 | NC State -6.5
  • Moneyline: Mississippi +250 | NC State -310
  • Over/Under: Over 146  | Under 146

Mississippi vs NC State betting trend to know

Eleven of the Wolfpack's last 13 games vs non-conference opponents have produced a total of 151+ points. Find more college basketball betting trends for Mississippi vs. NC State.

How to watch Mississippi vs NC State

Location First Horizon Coliseum, Greensboro, NC
Date Sunday, December 21, 2025
Tip-off 1:00 p.m. ET
TV ESPN

Mississippi vs NC State key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Eric Rosales - Covers
Betting Analyst

Eric has been involved in sports media in many different capacities since graduating from journalism school in 1999, back when getting your own column in a newspaper was still considered a thing. He doubled down and graduated from broadcast journalism school five years later, which led to a move to Toronto and a career with The Sports Network (TSN). From behind-the-scenes production work, he moved into the digital realm, where he had his own hoops column (At the Buzzer), while regularly live streaming and chatting with fans during broadcasts as the character known as LeBlog James. He was also a key contributor to TSN and CTV’s Olympic programming during the 2012 London Games.

Eric eventually found his way into the sports betting field in 2016 and has been a mainstay ever since. He was tagged on Twitter as a Top 10 NBA sharp during the 2021 season and has been interviewed about basketball and his handicapping process on shows from Vancouver to India. Eric is now a jack-of-all-sports at Covers, where his predictions span the alphabet soup: NFL, NBA, MLB, NHL, F1, WNBA, Euro, and Copa.

When making picks, he focuses on finding value first and foremost, and ensuring readers have all the information they need to make an informed choice.

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