The Oklahoma City Thunder host the San Antonio Spurs in Game 5, with concerns around OKC's biggest strength — its depth — heading into Tuesday.
Injuries to key guards and underperforming stars have made the Thunder vulnerable to San Antonio’s defensive schemes, as the series is now a best-of-three.
My Spurs vs. Thunder predictions see Game 5 playing much closer than the previous three contests, and my NBA picks are taking the points with the visiting Spurs on May 25.
Spurs vs Thunder Game 5 prediction
Spurs vs Thunder best bet: San Antonio Spurs +5.5 (-110)
Injuries to Jalen Williams and Ajay Mitchell have thrown a wrench in the Oklahoma City Thunders’ offense.
.@ShamsCharania provides an injury update on the Thunder's Jalen Williams and Ajay Mitchell 🏀 pic.twitter.com/71ACPWzxc4
— NBA on ESPN (@ESPNNBA) May 25, 2026
Without those guards, OKC lacks reliable ball handlers. That forces Shai Gilgeous-Alexander to play true point guard rather than off the ball, where he’s most dangerous.
The San Antonio Spurs are keeping SGA guessing with pressure but not fully committing to double teams. Gilgeous-Alexander hasn’t been able to get into a rhythm, shooting a collective 12-for-32 the past two games.
The rest of the Thunder’s starters aren’t picking up the slack. Meanwhile the Spurs are getting great contributions from their starting five.

Spurs vs Thunder Game 5 same-game parlay
Stephen Castle is back in his regular spot with the Spurs’ point guards healthy. Castle has been active on the glass in this series, pulling down five or more boards in each of the first three games.
He had three rebounds on 12 rebounding chances in Game 4, and projections sit as high as six rebounds in OKC on Tuesday.
Victor Wembanyama was much more aggressive on offense in Game 4, specifically from outside. He knocked down 3 of 7 attempts from distance and has made at least two triples in three of the first four games.
San Antonio is being conservative with Wemby on defense — limiting his amount of running around on close outs — in order to save his legs on the offensive end.
Game script says the Spurs are fighting from behind, needing big shots from their big man. Forecasts call for two 3-point makes from Wembanyama.
Spurs vs Thunder SGP
- Spurs +5.5
- Stephen Castle Over 4.5 rebounds
- Victor Wembanyama Over 1.5 threes
Spurs vs Thunder odds for Game 5
- Spread: Spurs +5.5 | Thunder -5.5
- Moneyline: Spurs +165 | Thunder -200
- Over/Under: Over 216 | Under 216
Spurs vs Thunder betting trend to know
The Spurs are 10-7 SU and 11-6 ATS as road underdogs on the year. Find more NBA betting trends for Spurs vs. Thunder.
How to watch Spurs vs Thunder Game 5
| Location | Paycom Center, Oklahoma City, OK |
| Date | Tuesday, May 26, 2026 |
| Tip-off | 8:30 p.m. ET |
| TV | NBC/Peacock |
Spurs vs Thunder latest injuries
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