Red Sox vs Yankees Picks and Predictions: Who Has Edge With Two Struggling Starters?

Jun 5, 2021 |
By: Zachary Cohen
Red Sox vs Yankees Picks and Predictions: Who Has Edge With Two Struggling Starters?
Eduardo Rodriguez has allowed at least four earned runs and has also given up at least seven hits in five of his last six outings.
Photo By - USA TODAY Sports
Eduardo Rodriguez has allowed at least four earned runs and has also given up at least seven hits in five of his last six outings.
Photo By - USA TODAY Sports

The Boston Red Sox won the first game in this three-game set with the New York Yankees, and now Aaron Boone’s team will look to even things up when the two meet at Yankee Stadium in the Bronx on Saturday, June 5. This is the greatest rivalry in sports and New York is going to be hungry for a win, so the atmosphere should be electric. 

Will Boston earn a victory tonight and secure the win in this series? Find out in our Red Sox vs. Yankees picks and predictions. 

Red Sox vs Yankees game info

Location: Yankee Stadium, New York City, NY
Date: Saturday, June 5, 2021
Time: 7:15 p.m. ET

Red Sox vs Yankees odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

Compare MLB odds before betting to ensure you get the best number.

Covers Writer Icon

MLB Sharp Money and Line Movement Report

By Patrick Everson

New York hit the TwinSpires odds board as -119 chalk and stretched out to -134. As of 6 p.m. ET, the Yankees are getting a modest majority of tickets at 54 percent, but a more notable share of the cash at 70 percent. The tottal moved from 9 to 9.5, with ticket count running almost 4/1 and money almost 5/1 on the Over.

Check out the full line movement for this game

Red Sox vs Yankees betting preview

Starting pitchers

Eduardo Rodriguez (5-4, 5.64 ERA): Rodriguez has been getting absolutely crushed lately, as the lefty has allowed at least four earned runs in five of his last six starts. Rodriguez has also given up at least seven hits in five of his last six, and he has issued five walks over his last two outings. Rodriguez has some impressive arm talent, but the Sox need better production from him. 

Jameson Taillon (1-4, 5.10 ERA): Taillon has struggled to find consistency in his first season with the Yankees, but he has been surprisingly good at Yankee Stadium, which is a tough place to pitch. On the year, Taillon is 1-1 with a 2.90 ERA at home and a miserable 0-3 with a 9.18 ERA on the road. While things haven’t been great for the 29-year-old this season, he can endear himself to Yankees fans by earning a victory over the Red Sox tonight, and he’ll likely be excited about this one being in the Bronx. 


Be sure to monitor the gametime conditions with our MLB weather info.

Key injuries

Red Sox: RP Ryan Brasier (out)
Yankees: OF Aaron Hicks (out), 1B Luke Voit (out), RP Darren O’Day (out), RP Zack Britton (out)
Find our latest MLB injury reports.

Betting trend to know

The Red Sox are 12-3 in their last 15 games against AL East opponents. Find more MLB betting trends for Red Sox vs. Yankees.

Moneyline pick

The Red Sox are sending Rodriguez to the mound in this game, and that has been a losing proposition for them in each of the last four starts he’s made. The lefty has had success in the big leagues before, but he might just be somewhat rusty after having missed the 2020 season with a COVID-related condition. Now, Rodriguez needs to find a way to get his groove back against the rival Yankees. And while it’s hard to back him in this game, the line sure does suggest that Boston is the sharper side here. 

As mentioned earlier, Taillon has been excellent when pitching at Yankee Stadium this season, so New York has the edge on the mound on paper. However, the Yankees are only small favorites at home in this one, making this line just too good to be true. Also, for what it’s worth, Boston does have two options that could give Taillon some trouble in this one. Danny Santana and Hunter Renfroe are a combined 5 for 9 with two doubles, two homers and two RBI against the righty in their careers, and then there’s also Alex Verdugo, who is extremely good against right-handed pitchers. The Sox also have Xander Bogaerts, who is good against everyone. 

Not only does this Boston lineup pose a threat to Taillon, but Rodriguez has also been solid at Yankee Stadium in his career. In nine starts in the Bronx, he has a 3.96 ERA, and that number could be a lot worse with how easy it is to hit there. Perhaps the adrenaline in this game is what he needs to get this year back on track. 


Over/Under pick

Even if Rodriguez is able to help his team come away with a win at Yankee Stadium, it’s highly unlikely that he’ll do so without allowing the Yankees to score a couple of runs. A quality start would be a huge win for Boston in this game, but even that would mean he potentially gave up three earned — but four is probably more likely.

Meanwhile, the Red Sox should be able to get their bats going against Taillon. That makes this total seem extremely reachable, even with both teams having bullpens that are performing at high levels this season. 

PREDICTION: Over 9.0 (-114) 

Red Sox vs Yankees betting card

  • Red Sox ML +110
  • Over 9.0 (-114) 

Picks made on 6/6/2021 at 1:45 a.m. ET

MLB parlays

Did you know that if you parlayed today’s MLB Red Sox vs. Yankees picks, you could win $29.42 on a $10 bet?

Use our MLB parlay calculator to create your own parlays and see their potential payouts.

Where can I bet on MLB odds?

You can bet on MLB odds at every online and casino sportsbook, including MLB moneylines, runlines, Over/Under totals, and a ton of MLB prop odds. Head over to our best-suggested sportsbooks for the top spots to bet on MLB odds in your area.

Recent MLB Headlines

Covers 25 Years Logo Established in 1995,
Covers is the world
leader in sports
betting information.
Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo