The Baltimore Orioles head to the Bronx for the last three games of the regular season, and forecasts of bad weather over the weekend have turned Friday's opening game into a doubleheader.
My Orioles vs. Yankees predictions and MLB picks call for the Orioles to get a win as both teams play out the string.
Who will win Orioles vs Yankees today: Orioles moneyline
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This game will likely be treated like an exhibition on the back fields of spring training, so I'll take the Baltimore Orioles as long as they're the underdog in what amounts to a toss-up.
Baltimore is eliminated, and starter Trevor Rogers has a 2.57 ERA and sub-0.900 WHIP over the last month.
The New York Yankees are locked into their playoff slot and seem more worried about resting their pitching and getting it in order for the Wild Card series.
New York starts rookie Brendan Beck in the opener, and it will be a surprise if anyone expected to pitch for the Yankees against Boston next week appears in the game.
COVERS INTEL: Beck's fastball showed below-average velocity in the minors and was about 92.5 mph in his first few MLB appearances. His movement is also below average for his fastball and sinker. All of the pitches in his arsenal generate more fly balls than average, which explains the home runs he's been allowing.
Orioles vs Yankees Over/Under pick: Over 6.5
The totals cutoff is extremely low, especially considering the pitchers the Yankees will be sending out in the opening game. New York has been Over in nine of its last 10 games and has scored six runs on its own in five of 10.
Beck, a 27-year-old journeyman, has allowed four home runs, seven runs and five walks in 7 2/3 big league innings.
Rogers has been hit harder on the road, giving up a 4.48 ERA and .739 OPS, compared to 3.76 and .665 at home. He also gives up homers about 7% more often away from Baltimore, and his 13.50 career ERA against the Yankees is his highest against any team.
They have a 1.095 OPS and 201 OPS+ against him.
Orioles vs Yankees home run prediction: Pete Alonso
The Yankees likely won't be giving many at-bats to their regulars, so we're going with the Orioles' hottest slugger.
Pete Alonso has four homers in the last seven days and seven in the last two weeks. The longtime Met clearly loves hitting in New York—he got his 300th career blast at Citi Field last week.
He has two home runs in four career games at Yankee Stadium, with a 1.295 OPS and a 252 OPS+. Beck has faced 18 right-handers in MLB and given up three home runs to them.
- ML/RL picks: 33-41, -2.77 units
- Over/Under picks: 45-24 +8.80 units
Orioles vs Yankees weather
This weekend will be bad, but there won't be any rain today. Temps will drop from a 63-degree high by the time this game starts at 4. Winds will be 17 mph and could gust much higher.
Orioles vs Yankees odds
- Moneyline: Orioles 48% | Yankees 52%
- Run line: Orioles -1.5 (33%) | Yankees -1.5 (34%)
- Over/Under: Over 6.5 (55%) | Under 6.5 (45%)
Orioles vs Yankees trend
The Baltimore Orioles have hit the Moneyline in 27 of their last 45 away games (+11.50 Units / 23% ROI). Find more MLB betting trends for Orioles vs. Yankees.
How to watch Orioles vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Friday, September 25, 2026 |
| First pitch | 4:05 p.m. ET |
| TV | MASN, YES |
| Orioles starting pitcher | Trevor Rogers (10-11, 4.07 ERA) |
| Yankees starting pitcher | Brendan Beck (0-1, 8.22 ERA) |
Orioles vs Yankees latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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