Mets vs Padres Prediction, Picks & Odds for Today's MLB Game

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst 17+ years betting experience
Updated: Jun 6, 2026 , 11:59 AM ET • 4 min read

Griffin Canning's struggles are set to continue against his former team.

MLB

Match starts: 8 hrs
NYM
51 %
SD
49 %
EXPERT PICK - MONEYLINE
NY Mets -124 NY Mets -124
Bet Now
San Diego Padres starting pitcher Griffin Canning (17) reacts after giving up a run.
Photo By - Reuters Connect. San Diego Padres starting pitcher Griffin Canning (17) reacts after giving up a run.

The New York Mets will look to extend their winning streak to three games as they visit the San Diego Padres tonight.

Griffin Canning hasn't found his rhythm on the mound this season, and I'm backing New York to get the better of him once again in my Mets vs. Padres predictions.

Read on for my full breakdown and free MLB picks for Saturday, June 6.

Who will win Mets vs Padres today: Mets (-124)

Griffin Canning (0-4, 7.16 ERA) has been an absolute disaster for the San Diego Padres.

Batters are teeing off on him, boasting an average exit velocity of 92.4 mph and an 11.5% barrel rate. When the struggling right-hander is not giving up bombs, Canning is allowing 4.9 walks per nine innings.

Although New York Mets starter Nolan McLean (3-4, 4.21 ERA) has gone through a rough patch himself, his underlying numbers look good. The hard-throwing righty is striking out 10.4 batters per nine innings while holding opponents to a .291 xwOBA.

I expect the Mets to hit Canning hard and like them to win at -130 or better.

Covers COVERS INTEL: The Mets rank third in the majors in hard-hit percentage (41.7%), and Canning surrenders hard contact 48.7% of the time.

Enjoying Covers content? Add us as a preferred source on your Google account Add as a preferred source on Google

Mets vs Padres Over/Under pick: Under 7.5 (-110)

This is a matchup between what might be the league’s two worst offenses. The Padres (.289) and Mets (.292) are at the bottom of the league in wOBA, take up the worst two spots in OPS, and both have a heavy lean to the Under this year.

The Padres are dead last in run production (3.79 per game) and struggle against McLean’s signature pitch, pulling just 9.7% of sinkers in the air. Even if the Mets fare better against Canning, the Under is the clear play for me, and I’d back it to -120.

Ed Scimia's 2026 Transparency Record
  • ML/RL bets: 11-15, -4.66 units
  • Over/Under bets: 8-16, -8.40 units

Mets vs Padres odds

  • Moneyline: Mets -124 | Padres +106
  • Run line: Mets -1.5 (+134) | Padres +1.5 (-162)
  • Over/Under: Over 7.5 (-110) | Under 7.5 (-110)

Mets vs Padres trend

San Diego is 0-5 SU in Canning’s last five starts. Find more MLB betting trends for Mets vs. Padres.

How to watch Mets vs Padres and game info

Location Petco Park, San Diego, CA
Date Saturday, June 6, 2026
First pitch 10:10 p.m. ET
TV SNY, Padres.TV
Mets starting pitcher Nolan McLean
(3-4, 4.21 ERA)
Padres starting pitcher Griffin Canning
(0-4, 7.16 ERA)

Mets vs Padres latest injuries

Mets vs Padres weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo