Ernie Clement cashed his base total for a sixth time in his last seven games last night, and with a southpaw on the mound for Cleveland today, I’m expecting that trend to continue this afternoon.
Read on for my Toronto Blue Jays vs. Cleveland Guardians predictions and MLB picks for Saturday, April 25.
Guardians vs Blue Jays predictions
Guardians vs Blue Jays best bet: Ernie Clement O 1.5 total bases (+110)
If it ain’t broke, don’t fix it.
Toronto Blue Jays infielder Ernie Clement to go Over his base total has been a pretty safe bet over the past week, as he’s 6-1 to the Over in his last seven outings.
Throughout this seven-game stretch, Clement is averaging 2.57 bases per game with six extra-base hits.
With a hit rate like that, it’s too much value to pass up his bases total again at plus-money (+110).
Additionally, with Cleveland Guardians lefty Joey Cantillo on the mound, it’s a great matchup for Clement, too. He had a terrific .900 OPS against lefties last season and owns a .317 average against them again so far this year.
COVERS INTEL: Right-handed batters, like Clement, own a .786 OPS against Cantillo this season with six extra-base hits. 
Guardians vs Blue Jays same-game parlay (SGP)
When Kevin Gausman has his splitter dancing, he’s nearly unhittable. This is often the case when facing this lineup, which owns just a .196 average against him with 26 K’s in 92 at-bats.
I’ll take the Over 5.5 strikeouts tonight for Gausman against a team that struggles against the splitter.
I’ll double down on the Gausman strikeout market by taking Guardians' Bo Naylor to strike out. He struggles against Gausman, going 0-5 in his career with three K’s.
Guardians vs Blue Jays SGP
- Ernie Clement Over 1.5 total bases
- Kevin Gausman Over 5.5 strikeouts
- Bo Naylor Over 0.5 strikeouts
Guardians vs Blue Jays home run pick: Kazuma Okamoto. (+425)
I’ll make this a half-unit wager.
Cantillo has been prone to giving up quite a bit of power. He ranks in the 31st percentile in hard-hit rate and in the 28th percentile in average exit velocity.
Enter Kazuma Okamoto.
The Jays third-baseman owns a .571 batting average against lefties who throw him that pitch with a 60% hard hit rate. He also owns a 1.107 OPS over the last seven days.
- Best bets: 6-18, -9.15 units
- SGPs: 3-21, -8.25 units
- HR picks: 4-20, -1.35 units
Guardians vs Blue Jays odds
- Moneyline: Cleveland +127 | Toronto -140
- Run line: Cleveland +1.5 (-165) | Toronto -1.5 (+145)
- Over/Under: Over 8 (-105) | Under 8 (-115)
Guardians vs Blue Jays trend
The Toronto Blue Jays have hit the Team Total Under in 13 of their last 20 games (+5.50 Units / 24% ROI). Find more MLB betting trends for Guardians vs. Blue Jays.
How to watch Guardians vs Blue Jays and game info
| Location | Rogers Centre, Toronto, ON |
| Date | Saturday, April 25, 2026 |
| First pitch | 3:07 p.m. ET |
| TV | Sportsnet One |
| Guardians starting pitcher | Joey Cantillo (1-0, 3.20 ERA) |
| Blue Jays starting pitcher | Kevin Gausman (1-1, 2.54 ERA) |
Guardians vs Blue Jays latest injuries
Guardians vs Blue Jays weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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