The Milwaukee Brewers and Boston Red Sox face off in the second game of a three-game set at Fenway Park on Tuesday night.
Milwaukee took the series opener, and my Brewers vs. Red Sox predictions are backing the visitors to win again behind a strong effort from Jacob Misiorowski.
Here are my best free MLB picks for this interleague showdown on April 7.
Who will win Brewers vs Red Sox today: Brewers moneyline (+136)
The 2-8 Boston Red Sox are favored because ace Garrett Crochet is on the mound, but the difference in the starters isn't as big as you might think.
Milwaukee Brewers righty Jacob Misiorowski has allowed three runs on six hits with 18 strikeouts through 11 innings. The analytics indicate those numbers are sustainable with the hard-throwing 24-year-old allowing an xBA of .167.
Milwaukee has a big edge with its lineup ranked third in the majors in OPS (.813) and second in runs per game (6.80).
With the Brewers boasting an 8-2 record, they have value as road dogs.
COVERS INTEL: Misiorowski is in the 94th percentile in strikeout rate (40%) and whiff rate (42.2%). Boston ranks 26th in strikeout rate (27.8%) and dead-last in whiff rate (33.3%).
Brewers vs Red Sox Over/Under pick: Under 7 (-110)
Crochet pitched to a sparkling 2.59 ERA in 32 starts last year. He's coming off an ugly start, but that was against a Houston team that usually crushes lefties.
The 2025 AL Cy Young runner-up should bounce back with a better performance at home.
Misiorowski and a strong Milwaukee bullpen will also shut down a Boston lineup that averages just 3.60 runs per game with an OPS of .682.
Misiorowski struggles with control at times, but the Red Sox are just 26th in walk rate and will chase pitches outside the strike zone.
- ML/RL bets: 3-2, +0.3 units
- Over/Under bets: 1-0, +1 units
Brewers vs Red Sox odds
- Moneyline: Milwaukee +138 | Boston -144
- Run line: Milwaukee +1.5 (-163) | Boston -1.5 (+156)
- Over/Under: Over 7.5 (+133) | Under 7.5 (-138)
Brewers vs Red Sox trend
The Red Sox have gone Under their team total in 48 of their last 78 games at home (+13.55 Units / 15% ROI). Find more MLB betting trends for Brewers vs. Red Sox.
How to watch Brewers vs Red Sox and game info
| Location | Fenway Park, Boston, MA |
| Date | Tuesday, April 7, 2026 |
| First pitch | 6:45 p.m. ET |
| TV | BREW, NESN |
| Brewers starting pitcher | Jacob Misiorowski (1-0, 2.45 ERA) |
| Red Sox starting pitcher | Garrett Crochet (1-1, 3.27 ERA) |
Brewers vs Red Sox latest injuries
Brewers vs Red Sox weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
