UFC 266 Andrade vs Calvillo Picks: Here For a Good Time, Also a Long Time

While Valentina Shevchenko cleans out the flyweight division, Jessica Andrade and Cynthia Calvillo square off at UFC 266, hoping to get a shot at the throne. Find out how to get the best value from this fight with our Andrade vs Calvillo picks.

Last Updated: Sep 24, 2021 2:07 PM ET Read Time: 5 min

Jessica Andrade vs. Cynthia Calvillo is on the main card for UFC 266 betting on September 25 from the T-Mobile Arena in Las Vegas, Nevada.

This is an interesting matchup and could be a stepping stone to a flyweight title shot for Calvillo, with current champ Valentina Shevchenko running out of contenders to destroy. Oddsmakers aren't counting on a Calvillo victory, however, with UFC betting odds installing her as a +200 underdog while Andrade comes back at -250.

Here are our best free UFC 266: Andrade vs. Calvillo picks and predictions for Saturday, September 25.

Andrade vs Calvillo fight odds

Live odds courtesy of the Covers Line, an average comprised of odds from multiple sportsbooks.

Andrade vs Calvillo method of victory odds

Method of Victory Jessica Andrade Cynthia Calvillo
Win by KO/TKO +250 +1,300
Win by Points +135 +490
Win by Submission +1,200 +600
Draw +5,000 +5,000

Odds courtesy of FanDuel Sportsbook as of September 24, 2021.

Andrade vs Calvillo betting preview

Jessica Andrade is coming off a second-round TKO loss to Shevchenko at UFC 261 in April. Andrade won the UFC strawweight title with a bodyslam knockout of Rose Namajunas in 2019. However, she is just 1-3 since then, with a TKO loss to Weili Zhang, a split-decision defeat in the rematch with Namajunas, and a knockout victory over Katlyn Chookagian in her flyweight debut last October. 

The 30-year-old Andrade is a pressure fighter that uses her strength and power to bully her opponents, both standing up and on the mat.  

Cynthia Calvillo enters this fight as the No. 5 flyweight contender and is coming off a decision loss to Chookagian last November. The 34-year-old is 6-2-1 in the octagon, with three of those wins coming by way of submission. 

Calvillo is a well-rounded fighter that combines polished striking with effective ground-and-pound and dangerous grappling.

Andrade vs Calvillo tale of the tape

Jessica Andrade   Cynthia Calvillo
30 Age 34
5-foot-1 Height 5-foot-4
125 lbs Weight 125 lbs
62 inches Reach 64 inches
2-9-0 (8 KO) Record 9-2-1 (2 KO)

Andrade vs Calvillo UFC predictions and betting picks

PREDICTION: Fight to go the distance (-128) - Andrade is a rare female fighter that (win or lose) ends fights early. Five of her last six fights have ended within the first two rounds. That said, Calvillo has never been finished in her career and her best chance of victory is avoiding a firefight with Andrade and her power shots.

Calvillo is a good wrestler who can be very dangerous with submission attempts if she takes the back. While she was unable to implement that game plan against Chookagian due to the reach disparity, she will find it easier to get her hands on the stockier Andrade. Expect Calvillo to try to take this fight to the mat and drag this bout the distance.

Where can I bet on UFC odds?

Most online sportsbooks and casinos offer bets on UFC odds and props. While odds to win usually come out as soon as a fight is announced, prop bets become more readily available closer to an event. Check out the best sportsbooks available where you live and see what UFC bets they have available.

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