Isaac Guerendo

SF 49ers • #31 • Running Back

Active
Position Running Back
Height 6'0"
Weight 221
Age 25
Birthdate Jun 28, 2000
Birthplace Clayton, IN, USA

Isaac Guerendo Projections, Player Props and Stats

Next Matchup
San Francisco San Francisco @ N.Y. Giants N.Y. Giants
13:00 ET Nov 2, 2025
Odds last updated Thu, Oct 30 16:11 ET

Score a Touchdown Odds

Yes
0.0 / game
(2025-2026) avg
+1,100
bet365
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 4500
Oct 19 vs ATL ATL 0 2500
Oct 12 @ TB TB 0 2200
Oct 2 @ LA LA 0 3000
Sep 28 vs JAC JAC 0 2500
Sep 21 vs ARI ARI 0 2000
Sep 14 @ NO NO 0 1700
Sep 7 @ SEA SEA 0 1600
Jan 5 @ ARI ARI 0 165
Dec 30 vs DET DET 0 -140
Last 10 average

Receptions Made

0.0 / game
(2025-2026) avg
Date Opponent Rec Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 0 -
Dec 30 vs DET DET 4(o) 2.5
Last 10 average 0.4

Score First Touchdown Odds

Yes
0.0 / game
(2025-2026) avg
+6,600
bet365
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 10000
Oct 19 vs ATL ATL 0 10000
Oct 12 @ TB TB 0 10000
Oct 2 @ LA LA 0 10000
Sep 28 vs JAC JAC 0 10000
Sep 21 vs ARI ARI 0 10000
Sep 14 @ NO NO 0 8000
Sep 7 @ SEA SEA 0 8000
Jan 5 @ ARI ARI 0 850
Dec 30 vs DET DET 0 440
Last 10 average

Score Last Touchdown Odds

Yes
0.0 / game
(2025-2026) avg
+6,600
bet365
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 10000
Oct 19 vs ATL ATL 0 8000
Oct 12 @ TB TB 0 5500
Oct 2 @ LA LA 0 6500
Sep 28 vs JAC JAC 0 5000
Sep 21 vs ARI ARI 0 5000
Sep 14 @ NO NO 0 3500
Sep 7 @ SEA SEA 0 4000
Jan 5 @ ARI ARI 0 650
Dec 30 vs DET DET 0 600
Last 10 average

Score 2+ Touchdowns Odds

Yes
0.0 / game
(2025-2026) avg
+12,500
bet365
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 25000
Oct 19 vs ATL ATL 0 20000
Oct 12 @ TB TB 0 14000
Oct 2 @ LA LA 0 20000
Sep 28 vs JAC JAC 0 11000
Sep 21 vs ARI ARI 0 14000
Sep 14 @ NO NO 0 12500
Sep 7 @ SEA SEA 0 2200
Jan 5 @ ARI ARI 0 750
Dec 30 vs DET DET 0 460
Last 10 average

Score 3+ Touchdowns Odds

Yes
0.0 / game
(2025-2026) avg
+15,000
bet365
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 25000
Oct 19 vs ATL ATL 0 25000
Oct 12 @ TB TB 0 25000
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 25000
Sep 21 vs ARI ARI 0 25000
Sep 14 @ NO NO 0 25000
Sep 7 @ SEA SEA 0 12500
Jan 5 @ ARI ARI 0 4000
Dec 30 vs DET DET 0 2700
Last 10 average

Receiving Yards

0.0 / game
(2025-2026) avg
Date Opponent Rec YDs Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 0 -
Dec 30 vs DET DET 65(o) 15.5
Last 10 average 6.5

Rushing Touchdowns

0.0 / game
(2025-2026) avg
Date Opponent TDs Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 0(u) 0.5
Dec 30 vs DET DET 0(u) 0.5
Last 10 average

Rushing Attempts

0.0 / game
(2025-2026) avg
Date Opponent Att Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 2 -
Dec 30 vs DET DET 9(u) 13.5
Last 10 average 1.1

Rushing Yards

0.0 / game
(2025-2026) avg
Date Opponent Rush YDs Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 5 -
Dec 30 vs DET DET 34(u) 57.5
Last 10 average 3.9

Rushing and Receiving Yards

0.0 / game
(2025-2026) avg
Date Opponent Rec YDs Close
Oct 26 @ HOU HOU 0 -
Oct 19 vs ATL ATL 0 -
Oct 12 @ TB TB 0 -
Oct 2 @ LA LA 0 -
Sep 28 vs JAC JAC 0 -
Sep 21 vs ARI ARI 0 -
Sep 14 @ NO NO 0 -
Sep 7 @ SEA SEA 0 -
Jan 5 @ ARI ARI 5 -
Dec 30 vs DET DET 99(o) 77.5
Last 10 average 10.4

Isaac Guerendo Game Logs

Receiving

Rushing
Date Opp Score TG Rec Yds TD LG Att Yds TD LG ATS O/U
Oct 26 @ HOU T 0 - 0 0 0 0 0 0 0 0 0 0 - -
Oct 19 vs ATL W 20 - 10 0 0 0 0 0 0 0 0 0 W 1 U 47.0
Oct 12 @ TB L 30 - 19 0 0 0 0 0 0 0 0 0 L 3 O 47.5
Oct 2 @ LA W 26 - 23 (OT) 0 0 0 0 0 0 0 0 0 W 8 O 44.0
Sep 28 vs JAC L 26 - 21 0 0 0 0 0 0 0 0 0 L -3 O 46.0
Sep 21 vs ARI W 16 - 15 0 0 0 0 0 0 0 0 0 L -2 U 44.5
Sep 14 @ NO W 26 - 21 0 0 0 0 0 0 0 0 0 W -3 O 40.5
Sep 7 @ SEA W 17 - 13 0 0 0 0 0 0 0 0 0 W -1 U 43.5
Last 8 Avg 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0

Isaac Guerendo's NFL career stats

Rushing

Receiving
Season Team G GS ATT YDS AVG LG TD REC YDS AVG LG TD
2025-2026 SF 8 0 0 0 - 0 0 0 0 - 0 0
2024-2025 SF 16 3 84 420 5.0 76 4 15 152 10.1 40 0


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