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Best NFL Picks Today

Find the best NFL bets today - Sept. 29, 2026. Free expert and computer picks for every NFL game.

New Computer Picks powered by Odds Shark

Predicted Score

PIT logo
PIT
PIT

19.31 @ 17.67

CLE
CLE logo
CLE

Steelers vs Browns · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

PIT logo
PIT
PIT

19.31

-2.5 -112

o37.5 -115

-142

CLE logo
CLE
CLE

17.67

+2.5 +100

u38.5 -109

+130

Indianapolis @ Washington
Matchup Stats

Predicted Score

IND logo
IND
IND

22.86 @ 19.76

WAS
WAS logo
WAS

Colts vs Commanders · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

IND logo
IND
IND

22.86

-3.5 -108

o46.5 -115

-180

WAS logo
WAS
WAS

19.76

+0.0 +150

u47.5 -115

+175

Arizona @ N.Y. Giants
Matchup Stats

Predicted Score

ARI logo
ARI
ARI

21.03 @ 19.44

NYG
NYG logo
NYG

Cardinals vs Giants · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

ARI logo
ARI
ARI

21.03

+1.5 -124

o43.5 -115

-110

NYG logo
NYG
NYG

19.44

-1.5 +102

u44.5 -110

+105

New England @ Buffalo
Matchup Stats

Predicted Score

NE logo
NE
NE

22.08 @ 25.66

BUF
BUF logo
BUF

Patriots vs Bills · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NE logo
NE
NE

22.08

+6.5 +100

o48.0 -110

+270

BUF logo
BUF
BUF

25.66

-6.5 -115

u48.5 -110

-298

N.Y. Jets @ Chicago
Matchup Stats

Predicted Score

NYJ logo
NYJ
NYJ

19.31 @ 21.06

CHI
CHI logo
CHI

Jets vs Bears · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NYJ logo
NYJ
NYJ

19.31

+3.5 -118

o42.5 -115

+150

CHI logo
CHI
CHI

21.06

-3.5 +100

u43.5 -123

-170

Dallas @ Houston
Matchup Stats

Predicted Score

DAL logo
DAL
DAL

23.22 @ 28.02

HOU
HOU logo
HOU

Cowboys vs Texans · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

DAL logo
DAL
DAL

23.22

+2.5 -102

o47.5 -108

+125

HOU logo
HOU
HOU

28.02

-2.5 -110

u48.5 -115

-134

L.A. Rams @ Philadelphia
Matchup Stats

Predicted Score

LA logo
LA
LA

22.28 @ 20.61

PHI
PHI logo
PHI

Rams vs Eagles · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LA logo
LA
LA

22.28

-2.5 -125

o43.5 -118

-155

PHI logo
PHI
PHI

20.61

+0.0 +128

u44.5 -110

+140

Green Bay @ Tampa Bay
Matchup Stats

Predicted Score

GB logo
GB
GB

22.77 @ 21.94

TB
TB logo
TB

Packers vs Buccaneers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

GB logo
GB
GB

22.77

-3.5 -115

o39.5 -105

-192

TB logo
TB
TB

21.94

+3.5 -104

u40.0 -115

+170

Tennessee @ Baltimore
Matchup Stats

Predicted Score

TEN logo
TEN
TEN

15.53 @ 26.18

BAL
BAL logo
BAL

Titans vs Ravens · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

TEN logo
TEN
TEN

15.53

+11.5 -110

o43.5 -108

+550

BAL logo
BAL
BAL

26.18

-11.5 -106

u43.5 -105

-649

Jacksonville @ Cincinnati
Matchup Stats

Predicted Score

JAC logo
JAC
JAC

22.60 @ 26.36

CIN
CIN logo
CIN

Jaguars vs Bengals · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

JAC logo
JAC
JAC

22.60

+2.5 -103

o51.0 -110

+120

CIN logo
CIN
CIN

26.36

-2.5 -108

u51.5 -112

-132

Miami @ Minnesota
Matchup Stats

Predicted Score

MIA logo
MIA
MIA

15.03 @ 27.25

MIN
MIN logo
MIN

Dolphins vs Vikings · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIA logo
MIA
MIA

15.03

+11.5 -109

o38.5 -110

+525

MIN logo
MIN
MIN

27.25

-11.5 -105

u39.5 -113

-649

Kansas City @ Las Vegas
Matchup Stats

Predicted Score

KC logo
KC
KC

26.67 @ 22.38

LV
LV logo
LV

Chiefs vs Raiders · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

KC logo
KC
KC

26.67

-4.5 -105

o47.5 -110

-200

LV logo
LV
LV

22.38

+4.5 -108

u48.5 -115

+185

L.A. Chargers @ Seattle
Matchup Stats

Predicted Score

LAC logo
LAC
LAC

18.67 @ 24.91

SEA
SEA logo
SEA

Chargers vs Seahawks · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LAC logo
LAC
LAC

18.67

+7.5 -120

o42.5 -115

+280

SEA logo
SEA
SEA

24.91

-7.5 +105

u43.5 -114

-334

Denver @ San Francisco
Matchup Stats

Predicted Score

DEN logo
DEN
DEN

23.49 @ 24.79

SF
SF logo
SF

Broncos vs 49ers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

DEN logo
DEN
DEN

23.49

+3.5 -132

o46.5 -108

+130

SF logo
SF
SF

24.79

-3.5 -115

u47.0 -115

-142

Detroit @ Carolina
Matchup Stats

Predicted Score

DET logo
DET
DET

26.06 @ 23.09

CAR
CAR logo
CAR

Lions vs Panthers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

DET logo
DET
DET

26.06

-3.5 -110

o50.5 -105

-180

CAR logo
CAR
CAR

23.09

+3.5 -108

u50.5 -108

+164

Atlanta @ New Orleans
Matchup Stats

Predicted Score

ATL logo
ATL
ATL

23.79 @ 23.92

NO
NO logo
NO

Falcons vs Saints · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

ATL logo
ATL
ATL

23.79

+3.5 -132

o47.5 -115

+130

NO logo
NO
NO

23.92

-3.5 -114

u48.5 -108

-145

Pittsburgh Steelers image thumbnail PIT @ Cleveland Browns image thumbnail CLE Thu, Oct 1 • 8:15 PM ET
Spread
Pittsburgh Steelers image thumbnail PIT -2.5 (-116)
Best Odds
Pick made: 4 hours ago
Joe Osborne logo
Joe Osborne
Senior Betting Analyst

It might surprise you to hear that Aaron Rodgers and Mike McCarthy have been great playing on a short week! Rodgers is 13-6 straight up and 13-5-1 against the spread in Thursday starts, while McCarthy’s Cowboys went 7-3 SU on Thursdays. More recently, Rodgers has thrown nine touchdowns against two interceptions in his three Thursday appearances since 2024. Pittsburgh is coming off its best offensive game of the season against Cincinnati. Cleveland has won two straight, but a closer look at the box scores shows the Browns lost the yards-per-play battle in both.

Total
Pittsburgh Steelers image thumbnail Cleveland Browns image thumbnail u38.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

A short week is hard enough when you’re not a 40-year-old QB. Rodgers has little time to rest and ready for the Browns on Thursday. Expect the Steelers to ride the momentum of RB Jaylen Warren, who had 176 total yards in Week 3, as well as continue those shorter shots to the tight ends. Cleveland allowed only 4.9 yards per play to Carolina and was able to get solid pressure and collect three sacks in the win. That won’t leave much time in pocket for Rodgers to hit deeper throws. Deshaun Watson has been up and down the past two games. He faces a revamped Steelers defense playing a high rate of zone. Pittsburgh continues to generate takeaways, with two in the win over Cincinnati and six on the season. Some extended forecasts do show a 43% chance of rain showers in Cleveland for Thursday night with wind gusts up to 22 mph. I’m leaning Under and would like it even more if that wet weather shows up.

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Arizona Cardinals image thumbnail ARI @ New York Giants image thumbnail NYG Sun, Oct 4 • 1:00 PM ET
Total
Arizona Cardinals image thumbnail New York Giants image thumbnail u44.5 (-120)
Best Odds
Pick made: yesterday
Shawn Krest logo
Shawn Krest
Betting Analyst

Both teams are in the bottom four in the league in yards per play, yards per pass and penalty yardage on offense. But they're top five in time of possession. Expect lots of long drives that end in field goal attempts. 

Spread
Arizona Cardinals image thumbnail ARI -1.5 (-103)
Best Odds
Pick made: yesterday
Shawn Krest logo
Shawn Krest
Betting Analyst

The spread will likely increase as the week goes on, but I’d stick with Arizona until -2.5 and up to 55%. The Cardinals made No. 3 overall pick Jeremiyah Love their lead back this week, which should help production. Meanwhile, the Giants suffered another season-altering injury. 

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New England Patriots image thumbnail NE @ Buffalo Bills image thumbnail BUF Sun, Oct 4 • 1:00 PM ET
Total
New England Patriots image thumbnail Buffalo Bills image thumbnail u48.5 (-120)
Best Odds
Pick made: 22 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

While the Patriots offense has yet to show a sign of life, the defense has been serviceable. New England ranks fifth in total defense and seventh overall in success percentage, which means they should be able to limit Allen enough to go Under the number. We've all seen Maye's struggles so far this season, and with the Bills front seven wreaking havoc through the early parts of the year, I'm leaning on Greg Rosseau and Co. to disrupt Maye enough to get the job done. These two teams have gone Under in two of the last three matchups in this divisional rivalry - points will be tough to come by.

Spread
Buffalo Bills image thumbnail BUF -6.5 (-120)
Best Odds
Pick made: 22 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

After watching the New England Patriots through three weeks, there's no way I could muster up the courage to invest my hard-earned money on them against the Buffalo Bills. Drake Maye is a complete tirefire; he hasn't thrown a touchdown since Week 1 and already has six interceptions to his name. The Patriots are scoring just 12 points per game, good for last in the NFL, and rank 22nd in total offense. Suffice to say, things haven't gone as planned early on in the year. Meanwhile, the Bills are registering over 400 yards per game, and Josh Allen is the overwhelming favorite for NFL MVP odds. Buffalo is also coming off their best defensive performance of the season against the Los Angeles Chargers and is a perfect 3-0 against the spread. 

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New York Jets image thumbnail NYJ @ Chicago Bears image thumbnail CHI Sun, Oct 4 • 1:00 PM ET
Game Prop
Chicago Bears image thumbnail o23.5 Team Total (-107)
Best Odds
Pick made: 2 hours ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

The Jets defense struggled against a more dynamic offense from Detroit in Week 3, giving up 381 yards and 24 first downs while ranking 29th in EPA allowed per play. Former Lions offensive coordinator Ben Johnson and his play calling is a problem, even with Case Keenum under center. Chicago spread the ball around to eight different receivers while also mixing in unique run calls. With confidence in the QB3 rising, expect Johnson to take the training wheels off in Week 4.

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Jacksonville Jaguars image thumbnail JAC @ Cincinnati Bengals image thumbnail CIN Sun, Oct 4 • 1:00 PM ET
Total
Jacksonville Jaguars image thumbnail Cincinnati Bengals image thumbnail o51.5 (+101)
Best Odds
Pick made: 22 hours ago
Tom Oldfield logo
Tom Oldfield
Betting Analyst

Both teams have looked solid against the run, so the stage is set for Burrow and Trevor Lawrence to air it out on Sunday – and that game plan plays to both teams’ strengths.

The numbers back that up. The Bengals are averaging 26.7 PPG, while the Jaguars sit at 27.3 PPG, and the Over is 7-2-1 in the last 10 meetings between these squads.

Spread
Cincinnati Bengals image thumbnail CIN -2.5 (-116)
Best Odds
Pick made: 22 hours ago
Tom Oldfield logo
Tom Oldfield
Betting Analyst

A healthy Joe Burrow and the home edge at Paycor Stadium has been a winning formula for the Bengals - to the tune of a 24-17 SU career record - and I like the hosts to win by at least a field goal in this battle of AFC playoff contenders.

Cincinnati has covered the spread in its past four matchups against the Jaguars, and I'm not overreacting to the Week 3 results, where Jacksonville got a big assist from an out-of-sorts Drake Maye.

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Miami Dolphins image thumbnail MIA @ Minnesota Vikings image thumbnail MIN Sun, Oct 4 • 4:05 PM ET
Spread
Minnesota Vikings image thumbnail MIN -9.5 (-120)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

Miami just lost its biggest weapon in Achane, leaving Malik Willis to face this insane Vikings defense with little help. Minnesota's blitz-hefty schemes are humming and face a Dolphins offensive line that gave up nine sacks in the opening two games. Willis ranks among the worst QBs when blitzed at PFF. Justin Jefferson's injury status doesn't worry me as much in Week 4. If he does play, this spread jumps to key number of -10 and beyond.

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Denver Broncos image thumbnail DEN @ San Francisco 49ers image thumbnail SF Sun, Oct 4 • 4:25 PM ET
Total
Denver Broncos image thumbnail San Francisco 49ers image thumbnail o46.5 (-108)
Best Odds
Pick made: 19 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

Even against a strong Denver defense, the 49ers have the explosiveness to create scoring opportunities. It helps that they own the best red-zone offense in football - scoring 90% of their trips inside the 20. Denver shouldn't need a huge offensive performance to get this game over the number, either. Nix showed flashes on Sunday Night Football in his 16-0 comeback victory, and is in a groove after two straight wins. 

Spread
San Francisco 49ers image thumbnail SF -2.5 (-116)
Best Odds
Pick made: 19 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

The San Francisco 49ers have been remarkably efficient on offense, with Brock Purdy leading a unit that generates an NFL-best 7.35 yards per play while also ranking first with 0.32 EPA per play. While injuries are beginning to pile up, the 49ers received encouraging news regarding Mike Evans on Monday. His presence will provide a significant boost against a stingy Denver Broncos defense. My biggest concern remains Bo Nix, who won't have the luxury of overcoming another slow start against this San Francisco team. The 49ers also boast a top-five red-zone defense, giving me plenty of confidence in their ability to cover.

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Detroit Lions image thumbnail DET @ Carolina Panthers image thumbnail CAR Sun, Oct 4 • 8:20 PM ET
Game Prop
Detroit Lions image thumbnail o27.5 Team Total (-110)
Best Odds
Pick made: 36 minutes ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

Detroit is willing to win shootouts, as we’ve seen, and new offensive coordinator Drew Petzing is finding his groove. Quarterback Jared Goff spread the ball around to eight different options on Sunday, and it woke up the rest of the weapons, beyond Jahmyr Gibbs and Amon-Ra St. Brown. The Lions owned the fourth-highest EPA per play in Week 3 and aren’t leaving points on the table, boasting the sixth-highest TD rate inside the red zone to start the year. Carolina is short in the secondary and dead last in red zone defense, giving up a TD on almost 86% of their opponents' trips inside the 20-yard line. Detroit does the "lion's share" of the scoring to get this Sunday night game and gets Over its team total.

Total
Detroit Lions image thumbnail Carolina Panthers image thumbnail o50.5 (-105)
Best Odds
Pick made: yesterday
Neil Parker logo
Neil Parker
Betting Analyst

Pair a couple of injury-riddled defenses with two capable offenses, and there are going to be points on the board in this primetime Sunday Night Football bout. Detroit is averaging 31 points per game while ranking third in offensive success rate, and while Carolina hasn’t been quite as efficient, the Panthers have still hung 29.7 points per game. In particular, I value Panthers QB Bryce Young ranking eighth in adjusted EPA per play to go with a career-high 7.8 yards per attempt and 10.5 aDoT though three weeks. 

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For every matchup in an NFL season, our NFL computer produces selections for a variety of different betting angles. Our computer picks are based on a proprietary algorithm that values each team in the current week to produce moneyline, spread, and point total selections.

The table above, below the game picks, tracks our NFL computer's results over the last 100 games, outlining the record and profit for selections, based on $100 unit size. We track the profit based on both opening and closing lines for every matchup.

How to Use NFL Computer Picks

The easiest way to utilize our computer picks is to simply follow our selections for every matchup, what you'd call ailing the computer." But there are other ways to utilize our NFL computer picks, as well.

You can use our NFL computer as a jumping-off point to do more research into specific lines, cross-referencing with expert picks, which can be found above the selections for some matchups, recent NFL betting trends, and more.

As well, you can gauge the confidence of the matchup. The larger the projected score, the more confident the computer is in a specific pick.

Or, if you want to implement a system, betting only on underdogs, for example, you can look for matchups in which our computer likes the underdog to inform which picks you're going to hone in on for a given week.

We have these computer picks for every sport you're looking to wager on, as well:

Free Computer Picks by Odds Shark

Moneyline

NFL moneyline picks are the simplest way to get in on the NFL action. All you have to do is simply bet on which team you think will win the game.

For moneyline picks, the favorite is represented with a minus sign (-) in front of the odds, while the underdog has a plus (+). However, you don't get the same profit for picking an underdog compared to a favorite. If the favored team is -120, a $100 bet on them would pay out $80 in profit and $180 total, if they win the game. The underdog winning at +150 would pay out a $150 profit, $250 total.

We have a complete breakdown of how to read NFL moneyline odds for these NFL computer picks.

Spread

While moneyline picks are the simplest, picking NFL games against the spread is probably the most common wager for regular NFL bettors.

To bet an NFL spread, you wager on whether a team will win by a certain number of points or more or if they'll lose by fewer points than the spread. For example, if the spread is -6.5 for the New England Patriots, you would win the bet if they win the game by 7 points or more. Or if a team is +6.5, you're betting on if they'll win outright or lose by fewer than 6.5 points.

There is a correlation between moneyline odds and the spread, as books set these lines based on the same information.

You can read more about NFL spreads here.

Totals (Over/Under)

If you aren’t entirely sold on which NFL team will win or cover in an NFL game, you can still use our NFL computer picks to bet on the point total.

As opposed to taking a side, in total or Over/Under betting, you wager on whether both NFL teams will combine for a final score of more than (Over) or less than (Under) the total number of points set by oddsmakers.

The computer picks, and your handicapping of totals is more about how you think both teams will score points, not which team has the edge to win.

More NFL Picks & Betting Tools

Our NFL Computer Picks are a great way to place weekly football wagers, but you should also consider handicapping games yourself using some of our other tools. If you're looking to bet on long-term futures this football season, check out some of our other dedicated pages:

Best Football Betting Sites

If you’re ready to bet on NFL picks, you first need to find the right sportsbook. Our NFL betting sites guide offers secure banking, the best odds, bonuses, and reliable customer service options for you.

NFL Free Picks FAQs

When do we release our NFL picks?

Covers NFL picks are released two to three days before each game on the NFL schedule.

What kinds of NFL picks do we make?

Covers provides free NFL picks covering many markets, including point spreads, totals, moneylines, player props, and more.