Get free expert and computer MLB picks for every game on Aug. 21, 2026.
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.97 |
+132 
|
o5.5 -115 
|
+1.5 -185
|
|
3.78 |
-135 
|
u6.0 -105
|
-1.5 +175
|
Atlanta
Milwaukee
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.55 |
+230
|
o8.0 -110 
|
+4.0 -355
|
|
5.15 |
-210
|
u8.5 -120
|
-4.0 +236
|
St. Louis
Philadelphia
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.72 |
+230
|
o7.0 -115
|
+1.5 -120
|
|
4.86 |
-194 
|
u7.5 -115
|
-1.5 +115
|
Toronto
NY Yankees
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.13 |
+137
|
o7.5 -115
|
+1.5 -160
|
|
4.06 |
-142
|
u8.5 -154
|
-1.5 +150
|
Washington
Miami
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.08 |
+160
|
o7.0 -122 
|
+1.5 -135
|
|
4.61 |
-168
|
u7.5 -115
|
-1.5 +126
|
San Francisco
Boston
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.23 |
+116
|
o7.5 -115
|
+1.5 -185
|
|
4.73 |
-124
|
u8.0 -127
|
-1.5 +175
|
Tampa Bay
Baltimore
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.40 |
+135
|
o7.0 -205
|
+2.5 -265
|
|
4.60 |
-140
|
u8.0 -113
|
-2.5 +210
|
NY Mets
Chi. White Sox
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.63 |
+167
|
o7.0 -200
|
+3.5 -315
|
|
4.52 |
-175
|
u9.0 -184
|
-3.5 +245
|
Athletics
Houston
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.59 |
-108
|
o8.0 -120
|
-1.5 +150
|
|
4.96 |
+105
|
u8.5 -115
|
+1.5 -160
|
Detroit
Kansas City
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.78 |
+130
|
o7.5 +105
|
+1.5 -170
|
|
4.11 |
-135
|
u7.5 -115
|
-1.5 +160 
|
LA Angels
Texas
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
6.03 |
-150
|
o10.5 -110
|
-1.5 +100
|
|
5.05 |
+143
|
u10.5 +100
|
+1.5 -108
|
Cleveland
Colorado
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.65 |
+135
|
o8.0 -120 
|
+1.5 -155
|
|
4.66 |
-140
|
u8.5 -110
|
-1.5 +145
|
Cincinnati
Arizona
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.75 |
+133
|
o8.0 -115 
|
+1.5 -185
|
|
4.40 |
-115
|
u8.5 -115
|
-1.5 +165
|
Minnesota
San Diego
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
3.49 |
+210
|
o7.0 -194
|
+1.5 +100
|
|
5.36 |
-219
|
u11.0 -481
|
-1.5 -105
|
Pittsburgh
LA Dodgers
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
4.81 |
+100
|
o7.5 -115
|
+1.5 -220
|
|
4.31 |
-105
|
u8.5 -130
|
-1.5 +180
|
Chi. Cubs
Seattle
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Toronto
NY Yankees
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Atlanta
Milwaukee
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Washington
Miami
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
St. Louis
Philadelphia
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
LA Angels
Texas
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Tampa Bay
Baltimore
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
NY Mets
Chi. White Sox
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Athletics
Houston
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Pittsburgh
LA Dodgers
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Detroit
Kansas City
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Chi. Cubs
Seattle
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
San Francisco
Boston
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Cincinnati
Arizona
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Cleveland
Colorado
Predicted Score
Team |
Predicted Score |
ML |
Total |
Run Line |
|---|---|---|---|---|
|
|
-- |
-- |
-- |
-- |
|
|
-- |
-- |
-- |
-- |
Minnesota
San Diego
ATL
@
MIL
Fri, Aug 21 • 4:10 PM ET
Gary Sanchez o0.5 Total Home Runs (+500)
Chris Sale attacks right-handed bats with a steady dose of fastballs, and that’s good news for lefty-masher Gary Sanchez.
He has gone nuclear against four-seamers thrown by southpaws, barreling up more than 22% of the time while posting a .684 ISO.
I'd bet this to +480
o6.0 (-110)
Chris Sale is exceptional but he has averaged 5.5 innings of work over his last 10 starts, and Milwaukee’s patience at the plate should chase him in six innings or less.
That’d afford plenty of opportunity to scratch together runs against a bullpen sitting 25th in xFIP the last month.
Jacob Misiorowski is not immune to power, allowing multiple homers in three of the last seven starts.
I’d play the Over to -122.
STL
@
PHI
Fri, Aug 21 • 6:40 PM ET
TOR
@
NYY
Fri, Aug 21 • 7:05 PM ET
Kazuma Okamoto o0.5 Total Home Runs (+550)
Kazuma Okamoto has hit two homers in his last three games, and has one against Schlittler in his rookie season, too. Okamoto's in the 83rd percentile for barrel percentage (12.5%) and is in a good spot to go yard at Yankee Stadium... again.
o2.5 Team Total (-115)
Offense has come from the entire lineup over the last month and change, but nobody has been hotter than Alejandro Kirk, who has 15 hits, three homers, and nine RBI across his nine-game hit streak. Look for this team to scrape and claw to get three or more runs on the board, especially at one of the most hitter-friendly ballparks in the big leagues.
WAS
@
MIA
Fri, Aug 21 • 7:10 PM ET
SF
@
BOS
Fri, Aug 21 • 7:10 PM ET
o7.5 (+105)
Logan Webb's SIERA is 1.44 runs higher than his ERA over the past month, a sign regression could be looming for the veteran righty.
The San Francisco Giants aren’t the sexiest team on paper but their offense has quietly been potent on the road in August, ranking Top-6 in ISO and wOBA vs. righties.
Bet to -107.
Wilyer Abreu o0.5 Total Home Runs (+475)
Wilyer Abreu ranks in the 95th percentile or higher in xwOBA, xSLG, ISO, and hard hit rate against right-handed pitching over the last 30 days.
Logan Webb has predictably been more prone to conceding homers on the road, and Abreu went for extra bases in the only two head-to-head bats we’ve seen.
Bet to +450.
TB
@
BAL
Fri, Aug 21 • 7:15 PM ET
Freddy Peralta o2.5 Earned Runs Allowed (+110)
The Orioles are catching a great price against Freddy Peralta, who has struggled mightily since joining the Rays. Through his first three starts with Tampa Bay, Peralta owns a 7.53 ERA, 6.01 xERA and 1.47 WHIP while allowing a 49% hard-hit rate and 13.33% barrel rate. Baltimore has also been making plenty of hard contact, posting over a 45% hard-hit rate and nearly 10% barrel rate over its last 21 games. Despite a cold week, the Orioles still own a 116 wRC+, .339 wOBA and .773 OPS over their last 12 games. At +110, Baltimore is worth backing and fading Peralta.
Gunnar Henderson o0.5 Total Home Runs (+405)
Fifteen of the 20 homers Perlta has allowed have came against left-handed hitters across 83 innings, who have posted a .270/.332/.477 line, and he has surrendered a 19.2% pull-air rate. Gunnar Henderson is Baltimore's primary left-handed power bat, and Camden Yards is where Peralta's fastball problem gets punished, a that Gunnar has led the O's in hard-hit rate against. Play to +330.
NYM
@
CHW
Fri, Aug 21 • 7:40 PM ET
Randal Grichuk o0.5 Total Home Runs (+414)
Randal Grichuk remains an intriguing home run look against Mets left-hander Sean Manaea, despite the possibility of being pinch hit for later in the game. Grichuk is one of the highest-rated hitters on Batters-Box, covering over 91% of Manaea's arsenal. Against left-handed pitching over his last 30 plate appearances, he owns a .828 SLG and .380 ISO while generating a 50% hard-hit rate. Manaea has struggled against right-handed hitters, allowing a 51.5% hard-hit rate and 15.2% barrel rate over his last 60. The potential pinch-hit concern creates some risk, but Grichuk is still a strong look at +400 or better.
Miguel Vargas o1.5 Hits+Runs+RBIs (-114)
Miguel Vargas is my preferred right-handed hitter against Mets left-hander Sean Manaea tonight, with the possibility of Randal Grichuk being pinch-hit for making Vargas the better option. Vargas enters Friday with a .718 SLG, .410 ISO, 51.5% hard-hit rate and 12.1% barrel rate over his last ten games. He also carries an elite rating on Batters-Box, covering 100% of Manaea's pitches, while going over this prop 55.56% of the time this season when rated elite. Manaea has struggled against right-handed hitters, with his last 60 opponents producing a 51.5% hard-hit rate, 15.2% barrel rate and .360 xBA. The White Sox need to get back on track, and it starts with Vargas. Take this down to -125 if you have to.
ATH
@
HOU
Fri, Aug 21 • 8:10 PM ET
DET
@
KC
Fri, Aug 21 • 8:10 PM ET
Eduardo Valencia o0.5 Total Home Runs (+575)
Eduardo Valencia is hitting .358 against lefties with seven of 10 hits going for extra bases.
Valencia has been powerful against the changeup, and that’s Noah Cameron’s most-used pitch facing right-handed bats.
Kansas City's bullpen ranks dead last in HR/9 so Valencia will remain live even after Cameron departs.
Play to +550.
DET (-120)
Noah Cameron’s impressive run over the past month has been aided by an unsustainable .149 batting average on balls in play, miles below his .263 career output.
The Detroit Tigers sit fourth in wOBA the past 30 days and have already faced Cameron twice this season, better equipping them to produce.
Back Detroit to -130.
LAA
@
TEX
Fri, Aug 21 • 8:15 PM ET
CLE
@
COL
Fri, Aug 21 • 8:40 PM ET
Joey Cantillo o5.5 Strikeouts Thrown (-120)
Joey Cantillo draws another strong strikeout matchup against the Rockies in Denver. The Guardians southpaw has maintained a strikeout rate above 30% over his last five outings and owns a 25.44% strikeout rate away from home this season. Colorado has struggled against left-handed pitching, striking out 25.4% of the time at home this season. Over their last 60 at-bats against lefties, only two Rockies hitters own strikeout rates below 17%, while the rest sit at 25% or higher. Four hitters are striking out at a 31.7% clip, making six strikeouts an appealing target at -120 or better.
CIN
@
AZ
Fri, Aug 21 • 9:40 PM ET
AZ -1.5 (+146)
The numbers strongly favor Arizona to win comfortably tonight. Over the past month, the Diamondbacks rank first in home OPS and second against left-handed pitching, while Cincinnati ranks 27th on the road and 28th versus lefties. Eduardo Rodriguez also owns an ERA nearly two runs lower than Nick Lodolo, who has led the Reds to a 4-10 record in his starts. Throw in a struggling Reds bullpen, and we have the recipe for a lopsided Dbacks W.
MIN
@
SD
Fri, Aug 21 • 9:40 PM ET
PIT
@
LAD
Fri, Aug 21 • 10:10 PM ET
u8.5 (-131)
The Dodgers have cashed the Under in four consecutive Yoshinobu Yamamoto starts, and his splitter should work optimally in his matchup (Pittsburgh is 23rd in runs above average per 100 splitters seen). Bubba Chandler, meanwhile, has even better numbers than Yamamoto in their last six respective outings. Both bullpens rank in the top 10 in FIP over the last 14 days (L.A. 3.37, Pittsburgh 3.53) and are refreshed after Thursday's off day, so run suppression is a likely outcome of tonight's ballgame.
Bubba Chandler has allowed no more than three earned runs in any of his last six starts while turning in a 2.56 ERA, 2.39 FIP, and 2.3% barrel rate. The market is underpricing him against a slumping L.A. lineup (91 wRC+ in the last 14 days; Pittsburgh 104).
CHC
@
SEA
Fri, Aug 21 • 10:10 PM ET
CHC (-107)
Matthew Boyd has been struggling of late, serving up four home runs and seven earned runs in his last outing. But that poor performance may be exactly why we're catching an edge in the market for his next start, and I think the ballpark sets up well for him to bounce back. Boyd is known as a fly-ball pitcher, which makes him more vulnerable depending on the ballpark and weather conditions. A start at T-Mobile Park, where the marine layer can limit the carry on fly balls, is ideal for his pitching profile. Boyd's numbers haven't been great this season, but many of his poor outings have come at Wrigley Field. On the road, he's sporting a 2.57 ERA with just two home runs allowed, compared to 11 home runs allowed at Wrigley. The Cubs are trading at 51 cents on Polymarket, but I make them closer to a 54-cent favorite.
BOS
@
NYY
Sat, Aug 29 • 1:05 PM ET
o8.5 (-110)
The Yankees rank Top-3 in OPS, ISO, OBP, xWOBA, and hard hit rate when facing left-handed pitching. The Red Sox have hit righties very well over the past four weeks, sitting ninth in wOBA, ninth in ISO, and fourth in batting average. Play the Over to -120.
NYY (-135)
Ranger Suarez has started four games against teams ranking Top-10 in OPS vs. left-handed pitching, allowing 13 runs and posting a 6.13 ERA during those games. The New York Yankees lead the majors in OPS against lefties so they’re a prime candidate to cause Suarez problems. Playable to -145.
SF
@
ATL
Mon, Aug 31 • 6:05 PM ET
o7.5 (-116)
SF (+124)
The Braves have dropped five of six while averaging just 2.8 runs per game and ranking 29th in wOBA without Ronald Acuna Jr. (hamstring), and it’s been a smoke-and-mirrors start for veteran lefty Martin Perez, and there’s serious statistical correction ahead of his .230 BABIP and 80.2% strand rate considering they’re both high-end marks about pitchers with at least 60 innings this season. San Francisco is just the offense to kick-start the regression, too. The Giants are pacing the majors in wOBA and fourth in xwOBA over the past 30 days, after all.
Our experts and prediction models are hard at work analyzing the data. Check back shortly for today's picks, or explore our Computer Picks for inspiration.
Giants vs Red Sox Prediction, Picks & Odds for Today's MLB Game
Giants vs Red Sox Prediction, Picks & Odds for Today's MLB Game
MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.
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This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.
It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.
The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.
The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.
Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.
A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.
The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.
If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.
But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.
If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.
Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?
You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.
Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.
Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.
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