Week 15 of the NFL season is here. That’s why we’ve pulled every spread, moneyline, and total pick from our AI-powered Covers Predictions into one easy place. No more juggling tabs or second-guessing the numbers - just clear, data-driven edges from our super computers for every game on the board.
Lock in your NFL picks with confidence, then kick back, crack a cold one, and enjoy every NFL snap from kickoff to the final whistle, all Sunday long.
Week 15 NFL picks
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Lines courtesy of FanDuel.
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Falcons vs Buccaneers
Our computer model is expecting a squeaker with a final score forecast of Tampa Bay 22.93, Atlanta 19.99. That's good enough to win, but not enough to cover for a Bucs squad with a pitiful 5-8 ATS record this season.
Part of the blame lands squarely on the injured left shoulder of Baker Mayfield, who is averaging just 158 passing yards per game since getting roughed up by the Rams in Week 12.
View our Falcons vs. Buccaneers matchup hub for more stats and analysis prior to kickoff.
Raiders vs Eagles
Taking Las Vegas +12.5 with Philadelphia on the moneyline screams backdoor cover potential. Philly’s offense is explosive enough to control the game and justify the moneyline nod, but their defense has shown vulnerability to sustained drives and big plays. That mix keeps a huge spread dicey while still supporting a comfortable Eagles win.
With offensive talent on both sides and late garbage-time scoring always live, Over 38 looks very attainable if this opens up after halftime.
Check out our Raiders vs. Eagles matchup hub before game time.
Commanders vs Giants
Riding Washington both +2.5 and on the moneyline shows real faith in their offense versus New York’s inconsistent attack. Washington usually wants to push the ball vertically, but this matchup may be more about efficiency and avoiding turnovers.
The Giants’ offense has struggled to generate steady chunk plays, which props up Under 47.5. Expect a scrappy, field-position battle where Washington’s passing edge and red-zone execution tilt a one-score game their way.
Looking for more analysis? Check out our Commanders vs. Giants matchup hub.
Chargers vs Chiefs
Grabbing Los Angeles +5 but leaning Kansas City on the moneyline fits the classic script of this rivalry. The Chargers rarely get blown out, thanks to Justin Herbert and aggressive fourth-down mindset that keep them live late.
Still, Kansas City’s offensive ceiling and playmaking defense usually produce the key swing plays. That balance of shootout potential and late heroics makes Over 41.5 attractive, with both teams trading touchdowns before the Chiefs ultimately close the door.
View our Chargers vs. Chiefs matchup hub for more stats and analysis.
Browns vs Bears
An eight-point cushion on Cleveland with Chicago picked on the moneyline screams ugly, low-variance game. Both offenses lean run-heavy and can get bogged down on early downs, while Cleveland’s defense is usually physical enough to keep things tight. That profile dovetails perfectly with Under 39.5, suggesting punts, short fields, and red-zone stalls.
Chicago’s home-field edge and slightly steadier ground game earn the nod straight up, but the Browns plus the points look live in a one-score slog.
Find more stats, results, and trends on our Browns vs. Bears matchup hub.
Cardinals vs Texans
The model laying -9.5 with Houston and backing the Texans moneyline clearly trusts their offensive firepower. Houston’s passing game has evolved into a big-play machine, stretching defenses vertically and horizontally.
Arizona’s defense has often struggled to generate consistent pressure, which can snowball quickly if Houston jumps ahead. Over 42 fits a script where the Texans build a cushion and Arizona is forced to chase through the air. That creates extra possessions, more incompletions, and the kind of fourth-quarter scoring binge bettors love.
View our Cardinals vs. Texans matchup hub for more stats and analysis prior to kickoff.
Jets vs Jaguars
Taking New York +13.5 but siding with Jacksonville on the moneyline reflects confidence in the Jets’ defense keeping things respectable. New York’s pass rush and secondary can muddy the pocket and force Jacksonville into longer drives.
Offensively, though, the Jets still lack explosive consistency, which caps overall scoring and supports Under 42.5. Jacksonville’s balanced attack and red-zone options should still grind out a win, but asking them to cover two full touchdowns against this defense feels like too much.
Looking for more info? We have you covered on our Jets vs. Jaguars matchup hub.
Ravens vs Bengals
Bengals +3 with Baltimore on the moneyline perfectly captures how razor-thin this AFC North clash usually is. Cincinnati’s passing game can punish any secondary when the protection holds, making a field-goal spread very live. Baltimore, though, typically owns the edges in physicality, run-game design, and defensive disguises.
That combination can wear Cincinnati down over four quarters. Under 51.5 anticipates playoff-style intensity, more methodical red-zone trips, and coaches willing to take points instead of forcing shootout scripts in a rivalry spot.
Dive into our Ravens vs. Bengals matchup hub for more key stats and trends ahead of the game.
Bills vs Patriots
When the model lays just -1 with Buffalo and backs the Bills on the moneyline, it’s essentially saying talent wins out. Buffalo’s offense, with Josh Allen and vertical weapons, offers a much higher explosive ceiling than New England’s more methodical style.
Divisional familiarity usually keeps these meetings tight, though, with both defenses well-prepped for the other’s staples. That dynamic supports Under 50.5, anticipating more third-down chess and red-zone field goals than a full-blown track meet.
Bolster your handicap by visiting our Bills vs. Patriots matchup hub.
Panthers vs Saints
Laying -2.5 and backing Carolina on the moneyline suggests the model expects a mild offensive breakout. Bryce Young can stress New Orleans horizontally, especially if the run game shows signs of life.
Defensively, Carolina has been up-and-down, which opens the door for the Saints to answer with their own chunk plays and red-zone chances. That volatility on both sides nudges this toward Over 40.5, with Carolina doing just enough to sneak out the cover and win.
Browse our Panthers vs. Saints matchup hub to see more stats, picks, and up-to-the-minute odds.
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Colts vs Seahawks
Indianapolis catching +13.5 with Seattle on the moneyline screams potential for sneaky competitiveness. The Colts’ offense typically leans on tempo, misdirection, and a strong ground game, all of which can chew clock and generate enough scoring to stay within two touchdowns.
Seattle’s dynamic receivers and creative passing concepts justify the straight-up edge, especially at home. But a big number plus Indy’s willingness to be aggressive on fourth downs gives them backdoor-cover appeal. Over 42 follows naturally if both teams find success early on scripted drives.
See our Colts vs. Seahawks matchup hub for more news you can use.
Lions vs Rams
Detroit +6 with Los Angeles on the moneyline and a lofty Over 54.5 screams fireworks. Both offenses are built around motion, timing, and quarterbacks comfortable pushing the ball into tight windows. Playmakers at receiver and running back on both sidelines threaten quick strikes, while creative play callers can manufacture yards after the catch.
The Rams’ slight edge in trench play and defensive disguise explains the moneyline lean, but Detroit’s aggressiveness makes any multi-score spread feel fragile. Expect big swings, rapid scoring runs, and plenty of live-betting chaos.
Find the latest odds and stats on our Lions vs. Rams matchup hub.
Titans vs 49ers
Tennessee +13 with San Francisco on the moneyline fits the classic powerhouse-versus-grinder narrative. The 49ers’ roster is loaded with playmakers on both sides of the ball, so a straight-up win is the expectation.
Tennessee, however, usually leans on a physical run game and deliberate pace, shortening contests and muddying up margins. That helps justify grabbing two full touchdowns while still respecting San Francisco’s superiority. Under 44.5 lines up with a script where the 49ers control, the Titans shorten the game, and garbage-time fireworks never fully materialize.
Explore our Titans vs. 49ers matchup hub for advanced stats and betting angles ahead of kickoff.
Packers vs Broncos
Denver +2.5 paired with Green Bay on the moneyline suggests a swingy, high-leverage game. The Broncos getting points makes sense given their ability to generate splash plays on both offense and special teams, keeping them in striking distance throughout.
Green Bay’s young core on offense continues to trend upward, though, which justifies trusting them to close it out late. With both defenses prone to lapses, Over 42 feels live through busted coverages, extended scramble plays, and a few nerve-wracking drives in the fourth quarter.
Packers vs. Broncos matchup hub.
Vikings vs Cowboys
Laying -6.5 and backing Dallas on the moneyline shows real faith in the Cowboys’ firepower at home. Their vertical passing game and red-zone efficiency give them multiple paths to separation, especially if Minnesota’s offensive line struggles in pass protection.
The Vikings can still score with a creative scheme and explosive receivers, which keeps the backdoor and the Over 47.5 firmly in play. Script: Dallas builds a lead, Minnesota chases, and both quarterbacks keep the scoreboard humming.
View our Vikings vs. Cowboys matchup hub ahead of kickoff.
Dolphins vs Steelers
Taking Miami +3.5 while siding with Pittsburgh on the moneyline points to a grind-it-out AFC matchup. The Steelers’ formula leans on defense, field position, and just enough downfield shots to edge in front at home.
Miami’s speed and scheme still make them dangerous, but a physical Pittsburgh front can disrupt rhythm and force longer drives. That favors a one-score result and supports Under 42.5, with both teams trading punts, settling for field goals, and playing not to make the big mistake.
Check out our Dolphins vs. Steelers matchup hub for more stats and info.
Odds are correct at the time of publishing and are subject to change.
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