NFL Moneyline Picks for Every Week 7 Game

The Atlanta Falcons proved against Buffalo that they’re elite on both sides of the ball, and Trevor Knapp expects them to dominate an injury-riddled 49ers squad.

Trevor Knapp - Betting Analyst at Covers.com
Trevor Knapp • Betting Analyst
Oct 15, 2025 • 12:53 ET • 4 min read
Drake London Atlanta Falcons NFL
Photo By - Imagn Images. Atlanta Falcons wide receiver Drake London (5) celebrates after scoring a touchdown.

Two underdog wins on Monday Night Football pushed me to a 9-6 finish (+0.19 Units) last week, keeping me from the red, and my latest moneyline selections will once again back the Atlanta Falcons as they head to face the reeling San Francisco 49ers. 

Here are my latest NFL picks for the upcoming Week 7 slate.

Week 7 NFL moneyline picks

Matchup Pick
Steelers Steelers vs Bengals Bengals Steelers -240
Rams Rams vs Jaguars Jaguars Rams -148
Patriots Patriots vs Titans Titans  Patriots -360
Saints Saints vs Bears Bears  Bears -245
Dolphins Dolphins vs Browns Browns Browns -156
Panthers Panthers vs Jets Jets Panthers -124
Eagles Eagles vs Vikings Vikings Vikings +110
Raiders Raiders vs Chiefs Chiefs Chiefs -720
Giants Giants vs Broncos Broncos Broncos -340
Colts Colts vs Chargers Chargers Colts +112
Commanders Commanders vs Cowboys Cowboys Cowboys +108
Packers Packers vs Cardinals Cardinals Packers -300
Falcons Falcons vs 49ers 49ers Falcons +110
Buccaneers Buccaneers vs Lions Lions Lions -275
Texans Texans vs Seahawks Seahawks Texans +150

Lines courtesy of FanDuel as of 10-15.

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Expert Week 7 NFL moneyline picks

Steelers vs. Bengals: Steelers (-240)

Joe Flacco may never retire at this rate, but going up against a healthy Steelers defense will surely have him thinking about it.

Aaron Rodgers has managed the game perfectly during Pittsburgh’s 5-1-2 start, and while it may be a boring product, it’s been an effective one for Mike Tomlin’s squad.

Rams vs. Jaguars: Rams (-148)

Sean McVay is set to take on his former OC Liam Coen, so this should be an interesting game of chess between the two offensive gurus.

Considering star linebacker Devin Lloyd will be sidelined for Jacksonville, I’ll take L.A. to prevail in London.

Patriots vs. Titans: Patriots (-360)

New England has won three straight, Drake Maye is emerging as a star, and Mike Vrabel returns to his old stomping grounds ready to lay waste to a decrepit Titans organization.

This one won't be remotely close. 

Saints vs. Bears: Bears (-245)

The Chicago Bears have caught fire with back-to-back wins, and a cupcake matchup against New Orleans should only boost Caleb Williams and Co.’s confidence moving forward.

Dolphins vs. Browns: Browns (-156) 

The Browns have failed to score more than 17 points in 11 straight games, yet I’m backing Cleveland's defense to deliver its first win of the season against Miami.

That’s how much of a tire fire the Dolphins are right now.

Panthers vs. Jets: Panthers (-124)

Aaron Glenn delivered the worst coaching performance I’ve ever seen in New York's latest loss to Denver.

Despite limited talent, Carolina has bought in under Dave Canales, and that will be enough to drop the Jets to 0-7.

Eagles vs. Vikings: Vikings (+110)

Carson Wentz revenge SZN?!

To be fully transparent, I wouldn’t touch Minnesota if the Eagles were at full strength, but injuries to DT Jalen Carter, CB Quinyen Mitchell, and G Landon Dickerson make the Vikings an appealing play at plus money.

Raiders vs. Chiefs: Chiefs (-720)

Kansas City resembled the Chiefs of old in their prime-time victory over Detroit.

The team is 8-2 SU against the Raiders in their last 10 head-to-head matchups, and that trend will stay in KC’s favor on Sunday.

Giants vs. Broncos: Broncos (-340)

Nik Bonitto and the Denver defense will feast on Jaxson Dart, giving the rookie sensation a bit of humble pie in the Mile High City. 

The Giants' defense has been getting torched both on the ground and through the air in 2025, so if there was ever a time for Bo Nix to find his footing, it’s this game. 


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Colts vs. Chargers: Colts (+112)

Los Angeles has been getting burned on the ground in 2025, and the Colts have the perfect weapon to exploit that in rushing leader Jonathan Taylor.

Expect Indy to give Jim Harbaugh a taste of his own medicine and dominate the time of possession in a grind-it-out win at SoFi Stadium.

Commanders vs. Cowboys: Cowboys (+108)

Neither one of these defenses inspires any confidence, so I'm going to take a shot on Dallas as a home dog.

Dak Prescott has been incredible to start the season, clearly outplaying Jayden Daniels heading into Week 7.

Packers vs. Cardinals: Cardinals (-300)

Jacoby Brissett and the Cardinals gave the Colts a good scare last week, but it’ll be much tougher going up against an elite  Packers’ pass rush. Marvin Harrison Jr. is also questionable for this one after suffering a concussion against Indy. 

The Cheeseheads continue to travel well, and State Farm Stadium has become a haven for opposing fans taking over.

Green Bay takes this one by double-digits. 

Falcons vs. 49ers: Falcons (+110)

Fred Warner is the latest 49ers star to suffer a catastrophic injury, and San Francisco’s freefall is set to continue against a Falcons team that has all the pieces offensively.

Meanwhile, Atlanta's defense has proven to be elite after completely dominating Josh Allen from the start on Monday Night Football.

Buccaneers vs. Lions: Lions (-275)

This is shaping up to be an incredible matchup at Ford Field, though the Lions’ secondary will take another hit with the suspension of Pro Bowl safety Brian Branch.

That said, Tampa Bay is missing its top three receivers, and its starting corners remain banged up heading into this potential playoff preview. I’ll ride with the Lions at home, with their offense doing the heavy lifting once again.

Texans vs. Seahawks: Texans (+150)

Houston has had a full week to prepare for Seattle, while the Seahawks are traveling back to the West Coast following a huge road win in Jacksonville.

It’s easy to focus on the Texans’ 2-3 record, but their defense has held opponents to 10 points or fewer in four of those games, and C.J. Stroud has looked more like his former self over Houston’s last two outings (both wins).

I like the Texans to grab a huge road win in the Emerald City, propelling them back into AFC South contention.

My NFL moneyline record is 61-32 this season for +8.32 units.

Odds are correct at the time of publishing and are subject to change.
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Trevor Knapp - Covers
Betting Analyst

Trevor joined the Covers content team as a publishing editor in early 2022. Growing up in Vancouver, he studied Broadcast and Online Journalism at the British Columbia Institute of Technology (BCIT), and interned with TSN and Sportsnet Radio while also writing for the Daily Hive.

An avid bettor of the MLB, NFL, and CFL, Trevor advises his fellow sports bettors to leave their hearts at the door and not hesitate to fade their favorite team. It's a strategy he follows regularly as an apathetic Indianapolis Colts and Toronto Blue Jays fan.

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