We have an intriguing matchup at Mile High with the New York Giants and Denver Broncos facing off.
Both teams secured wins last week, but the Broncos' victory over the Jets raised more questions than it answered, while the Giants continued to improve.
That’s why we’re expecting the Giants to cover the spread against a Broncos team who haven’t been able to be consistent throughout games.
Don’t miss our Giants vs. Broncos predictions and NFL picks for Sunday, October 19.
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Giants vs Broncos prediction
Giants vs Broncos Best bet: New York Giants +6 (-106)
For the New York Giants, there are two ways to view this season.
Pre-Jaxson Dart and post-Jaxson Dart, with the 2-4 Giants’ season transforming after the 25th overall pick in this year’s NFL Draft, replaced Russell Wilson as the starter.
The team lost all three games with Wilson under center, but with Dart as the starter, they’re 2-1 and have beaten two strong teams, the Eagles and Chargers, and suffered a surprise defeat to the Saints.
They’re a team still learning and improving, but they’ve covered in two of three games under Dart and have developed an aura, propelled by the personalities of their rookie quarterback and running back Cam Skattebo.
The Denver Broncos are 4-2 and level with the Chargers at the head of the AFC West, but they’ve been wildly inconsistent this season, despite winning their previous three games.
The defense has been sensational at times, but the offense is looking wildly inconsistent, with Bo Nix experiencing growing pains in his second year.
They narrowly beat the Jets 13-11 last Sunday, despite sacking Justin Fields nine times. The Giants’ offense is ascending right now, while, outside of the Eagles, the Broncos' four wins include victories over the Jets, Titans, and Jake Browning-led Bengals.
The Giants can cause an upset here, but we should be bullish on them at least covering the spread.
Giants vs Broncos same-game parlay
In addition to our best bet for Giants vs Broncos, we’re going to back Cam Skattebo to score a touchdown. The rookie running back has seized his opportunity with Tyrone Tracey going down and made the starting job his own, with five touchdowns to his name this season.
He’s got 15+ carries in his previous three games, even with Tracey returning last week, so he has the opportunity.
We’re also taking J.K. Dobbins to score. He’s the one consistent piece of the Broncos’ offense and has found the endzone in four games this season. The Giants have given up a rushing score in five of six games this season, and Dobbins is the workhorse back for the Broncos.
Giants vs Broncos SGP
- New York Giants +7
- Cam Skattebo anytime touchdown
- J.K. Dobbins anytime touchdown
Our big-ticket SGP: Wan'Dale!
Our lottery same-game parlay adds two further legs. We’re backing Theo Johnson to have Under 28.5 receiving yards. He’s only exceeded that number twice this season, and only three teams (who’ve played six games) have given up fewer yards to tight ends than the Broncos.
The final leg of this SGP is for Wan’Dale Robinson to hit the Over on his receiving yards. Robinson is averaging 58.5 receiving yards per game this season, and with Malik Nabers on IR, he is now the best receiver that Dart has available. He’s had 14 targets in two complete games without Nabers and will be a key part of the Giants’ game plan.
Giants vs Broncos SGP
- New York Giants +7
- Cam Skattebo anytime touchdown
- J.K. Dobbins anytime touchdown
- Theo Johnson Under 28.5 receiving yards
- Wan'Dale Robinson Over 45.5 receiving yards
Giants vs Broncos odds
- Spread: Giants +7.5 (-115) | Broncos -7.5 (-105)
- Moneyline: Giants +300 | Broncos -375
- Over/Under: Over 40.5 (-110) | Under 40.5 (-110)
More NFL picks and odds from Covers
Giants vs Broncos trend to know
The New York Giants have hit the 4Q game total Under in 11 of their last 17 games. Find more NFL betting trends for Giants vs. Broncos.
How to watch Giants vs Broncos
| Location | Empower Field at Mile High, Denver, CO |
| Date | Sunday, October 19, 2025 |
| Kickoff | 4:05 p.m. ET |
| TV | CBS |
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