Against all odds, the San Francisco 49ers find themselves facing the Seattle Seahawks for a trip to the NFC Championship, and I expect Christian McCaffrey & Co. to stun the oddsmakers when they hit the field on Saturday night.
Powered by the 49ers’ magic continuing, let’s dive into all four of my NFL picks for this weekend’s Divisional Round matchups.
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Divisional Round moneyline picks
| Matchup | Pick |
|---|---|
 Bills vs  Broncos |
-108 |
 49ers vs  Seahawks |
+285 |
 Texans vs  Patriots |
-174 |
 Rams vs  Bears |
-200 |
Lines courtesy of FanDuel.
Expert Divisional Round moneyline picks
Bills vs Broncos: Bills (-108)
A rematch of last year’s playoff showdown is in store, and while Denver has home-field advantage this time around, I’m not betting against Josh Allen.
As good as Denver’s pass rush is, Buffalo’s O-line remains elite, and Allen is coming off one of his best playoff starts to date.
The Bills’ defense has proven it will bend but not break, so I’ll take Buffalo to survive the Mile High City.
49ers vs Seahawks: 49ers (+285)
Kyle Shanahan and Robert Saleh continue to work their magic in San Francisco, most recently coaching their asses off in a thrilling win over Philadelphia.
No Fred Warner? No Nick Bosa? Brandon Aiyuk MIA? No problem for Bang Bang Niner Gang.
This is just Sam Darnold’s second career playoff start, and we all know how the first one went. The Seahawks being favored by a full touchdown screams impending letdown.
I’m betting on the underdogs to pull off another miracle.
Texans vs Patriots: Patriots (-174)
Concussions to both Texans WR1 Nico Collins and Patriots CB1 Christian Gonzalez essentially cancel each other out, but the combination of New England’s cold-weather advantage and stingy defense will force another poor outing from C.J. Stroud.
DeMeco Ryans’ team has been eliminated in the Divisional Round in consecutive seasons, and I see that trend continuing on Sunday.
Rams vs Bears: Rams (-200)
The Rams are going to have to play much better than what they showed against Carolina, but Matthew Stafford and the L.A. offense are going to absolutely shred the Bears on Sunday.
Chicago couldn’t stop a nosebleed in the first half against Green Bay, and poor second-half coaching from Matt LaFleur — along with a godly throw on 4th-and-8 by Caleb Williams — is the only reason the Bears are still alive.
