The San Francisco 49ers and Los Angeles Rams open their 2026 seasons tonight at 8:35 p.m. ET (Netflix) from the Melbourne Cricket Ground in Melbourne, Australia.
Our 49ers vs. Rams cheat sheet is your one-stop shop for this NFL Week 1 matchup, featuring live win probabilities via prediction market apps, the best anytime touchdown scorer markets, our 49ers vs. Rams expert picks, and more ahead of kickoff in Melbourne.
49ers vs Rams probabilities: Who will win in Melbourne?
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49ers vs Rams anytime touchdown scorers
| Anytime TD scorer |  Probability |
|---|---|
 Christian McCaffrey — 1+ touchdown |
55% |
 Kyren Williams — 1+ touchdown |
52% |
| Davante Adams — 1+ touchdown |
42% |
| Puka Nacua — 1+ touchdown |
40% |
| Blake Corum — 1+ touchdown |
35% |
| Mike Evans — 1+ touchdown |
30% |
| George Kittle — 1+ touchdown |
24% |
49ers vs Rams expert picks
| Expert pick | Probability |
|---|---|
| 49ers +3.5 |
49% |
| Over 47.5 |
51% |
| Davante Adams 1+ TD |
42% |
49ers vs Rams cheat sheet
Expert 49ers vs Rams picks
Here's everything you need to know to prepare for tonight's 49ers vs. Rams matchup in Melbourne:
- 49ers vs. Rams cheat sheet
- 49ers vs. Rams predictions and picks
- NFL Week 1 AI predictions
- NFL Week 1 moneyline picks
- NFL Week 1 injury updates
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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