Week 9 brings a must-watch AFC matchup as the Kansas City Chiefs and Buffalo Bills meet at Highmark Stadium on Sunday.
I’m eyeing Marquise Brown to find the end zone in his return for KC, while James Cook’s dominance for Buffalo should continue in this crucial contest.
Find out more in my Chiefs vs. Bills anytime touchdown picks for November 2.
Chiefs anytime touchdown pick
Marquise Brown (+500 at FanDuel)
Marquise Brown has been a key weapon for Patrick Mahomes in 2025, reeling in 32 receptions for 316 yards and four touchdowns this season.
He didn’t have a single target in Week 8 against the Washington Commanders, given the return of Rashee Rice, but KC’s passing offense will be more of a factor on Sunday.
The wideout may not always have a ton of catches in a single game, but he’s found the end zone three times in as many games dating back to October 12 against the Detroit Lions.
Mahomes usually makes a point of getting Brown involved, and it doesn’t take much for him to reel in a touchdown potentially..
Given Brown’s numbers, it’s worth a look here.
Bills anytime touchdown pick
James Cook anytime touchdown (-135 at FanDuel)
The Buffalo Bills paid James Cook in the offseason, and he’s proving to be worth every penny. The running back is averaging 5.9 yards per carry, and most notably, he’s run for seven touchdowns in as many games.
Cook is coming off a two-TD performance on October 26 against the Carolina Panthers, where he went for 216 rushing yards. The 26-year-old has found the end zone at least once in five of his seven appearances in ‘25.
The Chiefs are No. 11 in the league in most rushing yards allowed, and Cook has two career touchdowns against Kansas City across three meetings.
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