Bo Nix Odds, Picks & Same-Game Parlay for Monday Night Football

Tom Oldfield breaks down his favorite Bo Nix odds and offers his best same-game parlay for Monday Night Football between the Bengals and Broncos.

Tom Oldfield - Contributor at Covers.com
Tom Oldfield • Betting Analyst
Sep 29, 2025 • 08:20 ET • 4 min read
Denver Broncos quarterback Bo Nix (10) throws a pass in the second half.
Photo By - Imagn Images. Denver Broncos quarterback Bo Nix (10) throws a pass in the second half.

The Denver Broncos are having a tough time living up to the hype, and Bo Nix has to take a chunk of the blame as he works through a classic case of sophomore struggles.

After finishing with 29 touchdown passes and 12 interceptions as a rookie, Nix has already tossed three picks this year. Still, he’s walking into a great bounce-back spot on MNF against a Cincinnati Bengals defense that gave up 48 points to the Minnesota Vikings in Week 3.  

I’ve weighed up the Bo Nix odds, prop bets, and NFL picks for this Monday, September 29, matchup, and this feels like a chance for Sean Payton to take some of the pressure off his quarterback’s shoulders.

Bo Nix prop pick

Bo Nix best bet: Under 31.5 pass attempts (-125 at bet365)

Bo Nix surpassed expectations as a rookie by a wide margin, but the bar may have been raised too high, too soon for Year 2. While the Denver Broncos may still emerge as a Super Bowl threat, it’s time to pump the brakes on this offense’s ceiling.

Sean Payton has said all the right things about Nix’s performances this year, particularly around some of the near misses on overthrows. Even so, the Broncos would surely love to ask a little less of their QB – and this MNF clash against the Cincinnati Bengals sets up nicely to do so.

The Bengals have allowed 30.3 PPG, tied for sixth-most in the league, and I expect Denver to mix in a heavy dose of J.K. Dobbins and RJ Harvey in the ground game here, freeing up Nix to pick his spots against favorable matchups. 

That leads me to the Under on Nix’s passing attempts. He’s fallen short of this 31.5 number in his last two outings, including a 14-for-25 line last week against the Chargers, and the game script is unlikely to call for gunslinging heroics.

I don’t see the Broncos playing from behind in this contest, especially after what we saw from Jake Browning and the Bengals in Week 3, and that will limit what Nix needs to do as a passer.

Bo Nix same-game parlay

Bo Nix Under 31.5 pass attempts

Bo Nix Over 19.5 rush yards

J.K. Dobbins anytime TD

Nix is an underrated scrambler, and he provided a reminder last weekend with eight carries for 33 yards. He’s picked up 20+ rushing yards in six of his last seven contests, and he won’t hesitate to take off if Trey Hendrickson and this Bengals front seven collapse the pocket. Nix ended up with 31 rushing yards against Cincinnati last season.

The Broncos need to find more touches for Dobbins, who’s found the end zone in all three games this season and should continue to get goal-line work. After only tallying 11 carries in Week 3, I expect an uptick in usage for him, and I’ll take his anytime TD prop to wrap up my SGP.

Bet on MNF at bet365!

Your Monday Night Football bets are never ordinary at bet365! Sign up now and by placing $5 on your first bet, you get $200 in bonus bets — win or lose!

*Eligible U.S. locations only

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Tom Oldfield - Covers
Betting Analyst

Tom Oldfield’s sports writing journey over the past 20 years has taken him from the Premier League and Champions League to the NFL, NBA, WNBA and MLB, with a wide range of articles and betting previews. Tom has worked closely with London’s Sportsbeat sports news agency as well as (thrillingly!) covering the Toronto Raptors’ 2019 NBA championship run, and he has appeared on BBC World Service and The Back Page podcast.

A graduate of the University of Nottingham in the UK, he is the author of biographies on Cristiano Ronaldo, Rafael Nadal, Gary Neville and Cesc Fabregas, and he co-authors a long-running series of children’s soccer books with his brother, Matt.

As a regular bettor across the top sports leagues, particularly with FanDuel and bet365, he is well versed on all the major markets and the next big game is rarely far from his thoughts. The best betting advice he has received is to monitor multiple sportsbooks to grab the best possible value.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo