The Tulane Green Wave look to extend their three-game winning streak as they head to the Alamodome to face the UTSA Roadrunners in Thursday night AAC action.
Quarterback Jake Retzlaff has been finding success through the air, and my Tulane vs. UTSA predictions anticipate another strong performance from him in the passing game.
Read on for my college football picks for Thursday, October 30.
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Tulane vs UTSA prediction
Tulane vs UTSA best bet: Jake Retzlaff Over 1.5 touchdown passes (+106)
Jake Retzlaff has found his rhythm directing the Tulane Green Wave’s balanced offense, and his matchup against the UTSA Roadrunners sets up well for him to sling at least two touchdown passes.
The Roadrunners have allowed 16 passing touchdowns and 7.89 yards per attempt, ranking among the weaker secondaries in the AAC.
Retzlaff has seen a major spike in passing attempts and is averaging 7.4 yards per attempt, with explosive targets Shazz Preston and Omari Hayes, who can create separation and haul in scoring strikes.
Tulane converts 43% of its third downs and often finishes drives through the air, especially when defenses stack the box against its 180-yard rushing attack.
With UTSA’s secondary banged up and Tulane expected to move the ball efficiently through the air, Retzlaff should have plenty of opportunities to notch at least two touchdown passes for the third consecutive game.
Tulane vs UTSA same-game parlay
Preston has recorded more than 48 receiving yards in three of his previous five games and should do so again against this UTSA defense, allowing 12.5 yards per completion.
Retzlaff is mobile. He’s scampered for 52 or more yards in five of his seven games this season and meets a UTSA defense allowing slightly over five rushing yards per attempt.
Tulane vs UTSA SGP
- Jake Retzlaff Over 1.5 touchdown passes
- Shazz Preston Over 47.5 receiving yards
- Jake Retzlaff Over 51.5 rushing yards
Our deep-ball SGP: Everything's Jake
Retzlaff has scored eight touchdowns this season and has a rushing touchdown in two of his previous three games.
Green Wave running back Javin Gordon has scampered for three touchdowns and has snagged one scoring strike. He’s also scored touchdowns in two of his past three games.
Tulane vs UTSA SGP
- Jake Retzlaff Over 1.5 touchdown passes
- Shazz Preston Over 47.5 receiving yards
- Jake Retzlaff Over 51.5 rushing yards
- Jake Retzlaff anytime touchdown
- Javin Gordon anytime touchdown
Tulane vs UTSA game predictions
Tulane vs UTSA moneyline prediction
Tulane has everything it needs on both sides of the ball to beat a banged-up UTSA defense that’s lost four of its last five games.
Tulane vs UTSA spread prediction
This is a tough one because the +3.5 is a bad number. UTSA is 2-1-0 ATS at home, and I’m leaning toward the Roadrunners covering the spread at the Alamodome.
Tulane vs UTSA Over/Under prediction
I’m leaning toward the Under. UTSA’s low third-down conversion rate (37%) and Tulane’s 2-5-0 record to the Under have me leaning towards a lower-scoring contest.
Tulane vs UTSA odds
- Spread: Tulane -3.5 (-112) | UTSA +3.5 (-108)
- Moneyline: Tulane -168 | UTSA +142)
- Over/Under: Over 55.5 (-110) | Under 55.5 (-110)
Tulane vs UTSA trend to know
UTSA has covered the Spread in 6 of their last 7 games at home (+4.90 Units / 64% ROI). Find more college football betting trends for Tulane vs UTSA.
How to watch Tulane vs UTSA
| Location | Alamodome, San Antonio, TX | 
| Date | Thursday, October 30, 2025 | 
| Kickoff | 7:30 p.m. ET | 
| TV | ESPN | 
Tulane vs UTSA latest injuries
Tulane vs UTSA weather
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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