The New York Yankees are favored again at home tonight, but my Guardians vs. Yankees predictions believe this number looks too heavy.
Gerrit Cole has been excellent in two starts back from elbow surgery, but the Cleveland Guardians bring a contact-heavy approach that will make him work.
Here are my free MLB picks for Wednesday, June 3.
Who will win Guardians vs Yankees today: Guardians moneyline (+135)
I’m backing the Cleveland Guardians moneyline and would play it to +120.
This is the same matchup idea I used last night against Cam Schlittler: New York is lining up another arm whose success leans on chase, command, and swing-and-miss.
Gerrit Cole has opened with just over 12 scoreless innings, but that level is not sustainable while he rebuilds after elbow surgery.
Again, Cleveland has the second-lowest whiff rate at 22.9% and rarely chase, so the Guardians can again put balls in play, lengthen at-bats, and make a taxed favorite uncomfortable.

Guardians vs Yankees Over/Under pick: Under 7 (+102)
I see this as good to -110.
Cole is still Cole, and even though the Guardians will make him labor, this is still a guy who has allowed zero barrels since returning, with a 2.19 expected ERA. Cleveland’s contact profile is more annoying than explosive, after all, last night was the first time they scored more than four runs in 13 games.
On the other side, Gavin Williams’ contact quality is the concern, but his power stuff (88th percentile run value fastball) gives him a cleaner path against a less dangerous Yankees lineup as Aaron Judge remains sidelined.
- ML/RL bets: 26-21, +4.59 units
- Over/Under bets: 30-17, +15.07 units
Guardians vs Yankees odds
- Moneyline: Guardians +130 | Yankees -155
- Run line: Guardians +1.5 | Yankees -1.5
- Over/Under: Over 7.5 | Under 7.5
Guardians vs Yankees trend
The Guardians have hit the moneyline in 10 of their last 14 away games (+7.60 Units / 49% ROI). Find more MLB betting trends for Guardians vs. Yankees.
How to watch Guardians vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Wednesday, June 3, 2026 |
| First pitch | 7:05 p.m. ET |
| TV | YES Network, CLEGuardians.TV |
| Guardians starting pitcher | Gavin Williams (8-3, 3.07 ERA) |
| Yankees starting pitcher | Gerrit Cole (1-0, 0.00 ERA) |
Guardians vs Yankees latest injuries
Guardians vs Yankees weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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