James Madison vs Oregon Prediction, Picks & Odds for December 20 — CFP First Round

Caley's prediction: Davison, Ducks destroy Dukes.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Dec 19, 2025 • 09:32 ET • 4 min read

NCAAF

Match starts: 32 hrs
ORE
60 %
JMU
40 %
EXPERT PICK - PROP
Oregon o34.5  (-104) Oregon o34.5 (-104)
Read Analysis
Jordon Davison Oregon Ducks CFB
Photo By - Imagn Images. Jordon Davison of the Oregon Ducks runs with the ball.

A lot of people, particularly in the media, have complained about James Madison’s inclusion in the College Football Playoff. 

But I’m not about that. The Dukes earned their spot here and will be just as competitive as many of the ACC teams that could have ended up here (Join a conference, Notre Dame).

Unfortunately, my James Madison vs. Oregon predictions believe that JMU is a three-touchdown underdog for their first-round matchup against Oregon for a reason — the Ducks are a legit title contender and are getting healthy for a playoff run.

My college football picks for Saturday, December 20 break down how the Ducks will eventually overwhelm the Dukes in this first-round CFP matchup.

James Madison vs Oregon predictions for the CFP First Round

Who will win James Madison vs Oregon?

Oregon. This is a really good football team that is a legit contender to win the national championship. But this is wrong place, wrong time for JMU.

James Madison vs Oregon best bet: Oregon team total Over 34.5 (-104)

Let’s get this out of way — the James Madison Dukes deserve to be here.

They won the games in front of them. And would have been favored against several ACC opponents according to S&P+, including conference champions Duke.

The Oregon Ducks were always going to be big favorites in this matchup, because they are really damn good, not because JMU is a bad team.

The Ducks enter this first-round playoff matchup with an 11-1 record, the lone loss coming to the No. 1 ranked Indiana Hoosiers. Oregon has an elite defense with strong tackling, which should limit JMU’s propensity for explosive plays.

But today, I want to focus on what makes the Ducks fly — the offense.

The first several seasons of the Dan Lanning era have been highlighted by prolific passing attacks — first with Bo Nix, and then with Dillon Gabriel. Dante Moore has shown a lot of promise this season, and the Ducks could be getting some reinforcements at wide receiver.

But these Ducks fly on the ground. Oregon has arguably the best running game in the country, one that can wear you down over the course of a game, eventually leading to hitting some home runs.

Oregon enters this game leading the nation in both EPA per rush and success rate on rushes. They use a trio of talented backs in Noah Whittington, Jordon Davison, and Dierre Hill Jr., which keeps them fresh and relentless.

Now, James Madison has a solid defense, and dominated the Sun Belt this season, but they haven’t seen anything close to this Ducks offense. The best team they played was Louisville earlier in the season, and the Cardinals rank 59th in EPA per play.

With a healthy offensive line and the potential to get their top three receivers back, a balanced Ducks offense is going to be very hard to stop. Mix in playing in front of what should be a crazy crowd in Eugene and Lanning’s willingness to run up scores, and the Over on their team total of 34.5 looks like a great play here.

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James Madison vs Oregon same-game parlay

I mentioned the trio of talented Oregon running backs. Well, my favorite is Jordon Davison. The freshman is built like a truck and has gotten stronger as the year went on.

Davison finished the season with 535 yards at 6.1 yards per carry with 444 of those yards coming in his last seven games. He’s also become the Ducks' goal-line back and has found the end zone 13 times this season.

Taking Davison to go Over his rushing prop and to score another touchdown reads right into the game script for Oregon and makes all the sense in the world for this SGP.

James Madison vs Oregon SGP

  • Oregon team total Over 34.5
  • Jordon Davison Over 47.5 rushing yards
  • Jordon Davison anytime TD

Our deep-ball SGP: Davison double dips

To take this deep-ball SGP to the next level, let's elevate Davison to two touchdowns. And if someone scores for JMU, it's likely going to be Wayne Knight. 

James Madison vs Oregon SGP

  • Oregon team total Over 34.5
  • Jordon Davison Over 47.5 rushing yards
  • Jordon Davison 2+ TDs
  • Wayne Knight anytime TD

James Madison vs Oregon odds

  • Spread: James Madison +20.5 | Oregon -20.5
  • Moneyline: James Madison +1200 | Oregon -2500
  • Over/Under: Over 47.5 | Under 47.5

James Madison vs Oregon trend to know

James Madison has only hit the Over in five of its last 14 games for -3.80 Units and a -25% ROI. Find more college football betting trends for James Madison vs Oregon.

How to watch James Madison vs Oregon

Location Autzen Stadium, Eugene, OR
Date Saturday, December 20, 2025
Kickoff 7:30 p.m. ET
TV TNT

James Madison vs Oregon latest injuries

James Madison vs Oregon weather

Monitor gametime conditions with our College football weather info.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.

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