College Football Week 5 Odds, Consensus Picks, Injuries: Ranked Games Galore

Week 5 in college football betting is here, and there's an endless stream of info to take in with a huge slate of games. We're helping you out and delivering the most important college football odds, weather, and key injuries for Week 5 action.

Last Updated: Sep 30, 2022 5:30 PM ET Read Time: 4 min
Will Levis Kentucky Wildcats College Football
Photo By - USA TODAY Sports

Welcome back for another rundown of all things betting in college football. Week 5 will provide us with plenty of great games to sink our teeth into, and I'll be highlighting two of them while also providing some insights on other games around the league.

As always, I won't be telling you what side to bet on, but I'll be sure to let you know what you need to know before slapping some coin down.

Grab yourself a seat and get comfy, this weekend is going to be a wild ride.

Featured college football Week 5 odds

NC State vs Clemson

There are several games this week between ranked opponents, but the Wolfpack vs. the Tigers should prove to be a barnburner. Clemson stands as 6.5-point faves, but may not be able to be fully trusted after narrowly escaping a shootout against Wake Forest last week.

It's also important to note that although both sides are 4-0, they have a combined against the spread record of 3-5. Looking at the total, it originally opened up at 46 but has been bet down by at least a point at all books.

Kentucky vs Mississippi

Fans will be treated to a fun afternoon game between two ranked SEC teams sporting identical 4-0 records. Wildcats QB Will Levis has emerged as a legit NFL prospect, and now they'll have a returning Chris Rodriguez back at RB to bolster the ground game. With that said, Ole Miss stands as 6.5-point faves as the home team, with the total sitting at a high 54.5. 

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College football Week 5 news

Ian disruptions continue

After the horrific Hurricane Ian made landfall in Central Florida, SMU and UCF had their game pushed back to Sunday, but now it has been moved to a standalone game on Wednesday. However, both teams won't have to worry too much as they each share an off week following this game.

The spread currently sits at UCF -3.5 with a whopping total of 64.5. Those wanting to bet on this game will have to wait just a little longer.

Ranked teams showing out

Those who like to dip their toes in several games will be happy to know that this week has the most ranked games since 2017, with five on the agenda. There are several high-profile matchups, paving the way for an exciting betting slate with plenty of star power. The games are as follows:

College football Week 5 injuries

Alabama vs Arkansas

The undefeated Crimson Tide will do battle with the Razorbacks this weekend but maybe shorthanded on the defensive side of the ball. Byron Young and Jordan Battle left last week's outing with injuries and are currently sitting day-to-day ahead of tomorrow's game. They aren't for sure ruled out but it's something to monitor before hammering any Bama -16.5 bets.

Texas A&M vs Mississippi State

Devon Achane is going to be relied on heavily as the Aggies lost Ainias Smith for the season after a leg injury against Arkansas. That isn't great news for an A&M team that hasn't scored more than 24 points since its 31-0 win back in its first game. Currently sitting anywhere between +3.5 and +4.5, it may be the defense that has to keep this one close.

Check out our full College football injury reports.

College football Week 5 weather

Weatherman LaRusic is once again ready to bring you the info you need to know upon game time. As Florida still does its best to recuperate from Hurricane Ian, we'll look at the two matchups highlighted above and see what's in store up in the sky.

The only type of wetness NC State and Clemson need to worry about Saturday night is that of the sweat covering their bodies, as sunny skies are projected upon kickoff. However, it won't be too hot for those attending as it'll be a nice and crisp 69 degrees. 

Heading down to Missississippi, fans will be delighted to know it'll be bright and beautiful when the Wildcats claw their way into Vaught-Hemingway Stadium. Conditions will be a little dry however as humidity will sit around 30% during the game. 

For the remainder of college football action, there will be plenty of sunshine to go around, but expect some games to be a little damper as there are showers sprinkled throughout. Be sure to use our weather tracker below to check the status closer to game time, and as always, have fun and bet responsibly.

Until next week, Weatherman LaRusic, out!

See our fulllive college football weather info.

Top college football Week 5 consensus picks

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