While Brent Venables made his reputation with ruthless defenses, it may be an impressive offense that steadies his tenure as the Oklahoma Sooners head coach.
Nonetheless, a valiant defensive effort will be necessary to slow the Auburn Tigers, led by their own NFL-caliber offensive line and experienced quarterback.
My Auburn vs. Oklahoma predictions and college football picks trust both offensive lines and both quarterbacks more than either defense, creating a relatively high-scoring afternoon in Norman at kickoff at 3:30 ET on Saturday, September 20.
Auburn vs Oklahoma prediction
Auburn vs Oklahoma best bet: Over 46.5 (-110 at FanDuel)
We got spoiled. We, as college football fans, forgot how chaotic quarterback play can be, particularly behind offensive lines still trying to find chemistry.
The universal pandemic eligibility waiver created an era of greater experience than ever before in college football, and enjoying veteran quarterbacks behind established offensive lines became borderline typical.
It is not any longer.
Unless, perhaps, you are Auburn and Oklahoma. The right side of the Tigers’ offensive line, in particular, may as well already be ready for the NFL. And the Sooners have regained the push that helped define much of their last 25 years.
Courtesy of the transfer portal, both Auburn and Oklahoma employ veteran quarterbacks, the Tigers in fact trotting out the Sooners’ former quarterback in Jackson Arnold.
Both Arnold and his counterpart, John Mateer, are more than capable of adding an extra hat to the rushing attack, furthering these offenses’ dynamic options.
Simply put, no matchup with offensive lines like these and quarterbacks like these should feature a total below 49.
Stop taking quality line play and impressive quarterback performances as the standard. They are not. And offenses that can reliably trust them should be trusted to score points, particularly if they need to keep up with each other.
Auburn vs Oklahoma same-game parlay
Auburn may have the best rush defense in the country. At least, to this point, it has statistically showed that kind of strength, so expect Mateer to finish drives through the air.
On the other side of the ball, the Tigers are better running the ball than throwing it, and that has often meant Arnold does everything for the offense.
Auburn vs Oklahoma SGP
- Over 46.5
- John Mateer Over 1.5 passing touchdowns
- Jackson Arnold touchdown
Our deep-ball SGP: Sooners Come Out on Top
Arnold may simply need to do too much for Auburn these days.
At some point, Venables will find a way to stop the former Oklahoma quarterback, and then the Tigers will have no further recourse.
Meanwhile, the Sooners at least have a few notable receivers, and the threat of Deion Burks downfield should yield one tally.
Auburn vs Oklahoma SGP
- Over 46.5
- John Mateer Over 1.5 passing touchdowns
- Jackson Arnold anytime touchdown
- Deion Burks anytime touchdown
- Oklahoma moneyline
Auburn vs Oklahoma odds
- Spread: Auburn +6.5 | Oklahoma -6.5
- Moneyline: Auburn +210 | Oklahoma -260
- Over/Under: Over 46.5 | Under 46.5
Auburn vs Oklahoma trend to know
Venables won the coaching matchup with Hugh Freeze last year in all regards, winning 27-21 despite being a two-point road underdog. Find more college football betting trends for Auburn vs Oklahoma.
How to watch Auburn vs Oklahoma
| Location | Memorial Stadium, Norman, OK |
| Date | Saturday, September 20, 2025 |
| Kickoff | 3:30 p.m. ET |
| TV | ABC |
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