March Madness Odds 2026: Michigan, Arizona Roll Into Sweet 16

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst 8+ years betting experience
Updated: Mar 25, 2026 , 12:59 PM ET • 4 min read

With the March Madness bracket down to 16 teams, the latest odds are still running through top-seeded Michigan and Arizona.

Dusty May Michigan Wolverines Big Ten March Madness college basketball
Photo By - Reuters Connect. Michigan head coach Dusty May on the sidelines during a recent game.

The March Madness bracket is down to 16 teams.

Three No. 1 seeds remain after Florida fell to Iowa, and those three squads make up the top of the National Championship odds board.

Michigan still has the best odds to win March Madness, with Arizona and Duke next up in the latest college basketball odds ahead of the Sweet 16.

March Madness odds

Team bet365 Next Opponent
Michigan
Michigan
+300 No. 4 Alabama (Friday)
Arizona
Arizona
+325 No. 4 Arkansas (Thursday)
Duke
Duke
+400 No. 5 St. John's (Friday)
Houston
Houston
+700 No. 3 Illinois (Thursday)
Purdue
Purdue
+1400 No. 11 Texas (Thursday)
Illinois
Illinois
+1400 No. 2 Houston (Thursday)
Iowa State
Iowa State
+1600 No. 6 Tennessee (Friday)
UConn
UConn
+2500 No. 3 Michigan State (Friday)
Michigan State
Michigan State
+3000 No. 2 UConn (Friday)
SJU
St. John's
+3000 No. 1 Duke (Friday)
Arkansas
Arkansas
+4000 No. 1 Arizona (Thursday)

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How these odds have shifted

Duke had the best odds to win the NCAA Tournament heading into Round 1, but their odds jumped from +350 to +475 despite surviving a scare from Siena. The Blue Devils are clearly missing Patrick Ngongba II and Caleb Foster, who continue to nurse injuries.

In that time frame, Duke has been passed up by Arizona and Michigan in the March Madness winner odds. Michigan is up to +300, while Arizona is second on the board at +325 after taking down Utah State in Round 2.

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March Madness favorites

Michigan Michigan (+300)

Before their setback against Duke, Michigan's only stumble came in January against Wisconsin, and Yaxel Lendeborg & Co. responded by rattling off 11 consecutive wins en route to the No. 1 seed in the Midwest.

Michigan crushed Howard to jump-start its tournament and did the very same thing to Saint Louis in Round 2. Oddsmakers have taken notice and slotted them into the No. 1 spot, at least for now.

Arizona Arizona (+325)

The Wildcats sat atop the odds board and were undefeated before suffering back-to-back losses to No. 14 Kansas and No. 16 Texas Tech.

However, nine straight wins — including running the table to win the Big 12 Tournament  — have helped them reshape the narrative.

Arizona hasn't made it past the Sweet Sixteen in more than a decade, and this roster may be as well-positioned as any to get over the hump.

It looked like its tournament was in danger against Utah State, but the Wildcats ultimately prevailed, and now they face Arkansas with a spot in the Elite Eight on the line.

Duke Duke (+400)

The Blue Devils’ win over Michigan vaulted them to No. 1 in the latest AP Top 25, and they haven't looked back, earning an unsurprising No. 1 seed in the East Region.

Cameron Boozer is the player to watch in Durham, emerging as one of the most highly-touted prospects for the upcoming NBA Draft. However, basketball is a team game, and the Blue Devils were clearly missing the injured Patrick Ngongba II and Caleb Foster in a close shave vs. No. 16 Siena.

The Blue Devils did cruise against No. 9 TCU in Round 2, though, and some time off could serve them well ahead of the Sweet Sixteen.

2026 March Madness futures bets

Bet Odds Bet Date Units
National Title: Michigan Michigan +450 Feb. 11 0.5
❌ Final Four: Kansas Kansas +350 Feb. 11 0.5
 ❌ To Make NCAA Tournament: USC USC -105 Feb. 11 0.5
West Region: Arizona Arizona -135 Mar. 18 1.0
Elite Eight: Iowa State Iowa State -115 Mar. 18 1.0

The Michigan Wolverines are atop nearly every rating system. Considering their size, experience, depth, and a 5-0 record against ranked opponents, I'm backing them to win the title with my predictions for March Madness.

With a healthy Darryn Peterson, the Kansas Jayhawks have looked like a title contender, and getting them at nearly 4:1 to make the Final Four would be a steal if he's at full strength by tourney time.

Sometimes, futures bets go like this. USC was 18-6 when this initial "make the tournament" wager was placed. but the Trojans went on to lose their final eight games of the season in an epic late-year meltdown.

Among Arizona, Duke, and Michigan, the Wildcats have the easier path to the Final Four. Arizona is at full strength, and its freshman seem to be hitting their stride. The Wildcats will power through the West Region, where every other top team has major flaws.

Unlike past versions of Iowa State, this squad rebounds at a high level and has the grit to win games when the shots aren't falling. The three toughest possible opponents on the road to the Elite Eight are Kentucky, Tennessee, and Virginia, and the Cyclones are rated significantly higher than all of them.

March Madness odds over time

March Madness betting splits

Highest ticket percentage:
•    Michigan 11.4%
•    Duke 10.0%
•    Arizona 8.7%

Highest handle percentage:
•    Arizona 14.4%
•    Michigan 14.0%
•    Florida 10.6%

All data courtesy of BetMGM.

Bettors have been banking big all season on the Wolverines, who have the highest ticket percentage and handle percentage in the nation.

Michigan spent all 19 weeks in the AP Top 25, starting out at No. 7 in the preseason and climbing to No. 1 in mid-February.

March Madness 2026 schedule

Event Date Location(s)
Selection Sunday March 15 --
First Four  March 17-18 UD Arena (Dayton, Ohio)
First Round March 19-20 Various
Second Round March 21-22 Various
Sweet 16 March 26-27 Toyota Center (Houston, Texas); SAP Center (San Jose, Calif.); United Center (Chicago, Ill.); Capital One Arena (Washington, D.C.)
Elite Eight March 28-29 Toyota Center (Houston, Texas); SAP Center (San Jose, Calif.); United Center (Chicago, Ill.); Capital One Arena (Washington, D.C.)
Final Four April 4 Lucas Oil Stadium (Indianapolis, Ind.)
National Championship Game April 6 Lucas Oil Stadium (Indianapolis, Ind.)

Popular March Madness markets


2026 March Madness opening odds

  • Houston +900
  • Duke +1000
  • UConn +1400
  • Louisville +1700
  • Auburn +1800
  • Florida +1900
  • Purdue +1900
  • Kansas +2000
  • Kentucky +2000
  • Arkansas +2000
  • BYU +2000
  • Alabama +2000
  • Michigan +2500
  • Texas Tech +2500
  • St. John's +2500
  • Gonzaga +3000
  • Michigan State +3000
  • Iowa State +3000
  • Arizona +4000
  • UCLA +4000
  • North Carolina +4000
  • Illinois +6000
  • Vanderbilt +15000
  • Iowa +15000
  • Nebraska +20000

Bookmakers had high hopes for Louisville entering the 2025-26 season, but the Cardinals have largely underperformed to the tune of a dismal 3-6 record against Top 25 teams. Their inability to hang with the best programs in the country doesn't bode well for their chances of playing in April.

Past March Madness winners

(Opening odds courtesy Sports Odds History)

Year Champion Opening odds Runner-Up
2025 Florida Florida +8000 Houston Houston
2024 UConn Connecticut +1100 Purdue Purdue
2023 UConn Connecticut +1600 San Diego State San Diego State
2022 Kansas Kansas +2000 UNC North Carolina
2021 Baylor Baylor +800 Gonzaga Gonzaga
2020 No tournament (COVID-19) N/A N/A
2019 Virginia Virginia +1800 Texas Tech Texas Tech
2018 Villanova Villanova +1200 Michigan Michigan
2017 UNC North Carolina +2400 Gonzaga Gonzaga
2016 Villanova Villanova +2000 UNC North Carolina
2015 Duke Duke +1000 Wisconsin Wisconsin

• Of the 20 teams that have entered the tournament with undefeated records, only seven have gone on to win the national championship.

• Only 13 teams successfully defended their national championship the following season.

• UCLA has the most NCAA titles of all time (11), although the Bruins have not won the tournament since 1995.

• A No. 1-seeded team has won the national championship 59.6% of the time since regional seeding was introduced in 1979.

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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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