College basketball betting is highlighted today by an ACC battle, where Louisville will be looking to prevent a three-game losing streak when the team hosts Duke at the KFC Yum! Center. The Blue Devils have also lost two games in a row coming into this one, so the sense of urgency will be high for both squads.
We break down the NCAA odds and give you our best free Duke vs. Louisville picks and predictions for Saturday, January 23, with tip-off set for 4:00 p.m. ET.
Duke Blue Devils at Louisville Cardinals Betting Preview
Key Injuries
Duke: Henry Coleman II F (Questionable).
Louisville: Aidan Igiehon F (Out), Malik Williams F (Out)
Find our latest NCAA basketball injury reports.
Betting Trend to Know
Duke is 1-7 ATS in its last eight road games. Find more NCAA betting trends for Duke vs. Louisville.
NCAAB Sharp Money and Line Movement Report
By Patrick EversonLouisville opened -2 late Friday night at DraftKings and reached -3 this morning, then ticked back to -2.5, where the number is at 1 p.m. ET, three hours before tipoff. Ticket count is running 4/1 and money 5/1 on the Cardinals for this ACC clash. The total hasn't budged off of 141, despite 93 percent of early bets and 98 percent of early money flowing toward the Over.
Check out the full line movement for this gameAgainst the Spread (ATS) Pick
The Blue Devils are 1-8 ATS this season, having failed to cover in each of their last four games, and they now take on a Cardinals team that is looking to avoid a three-game losing streak. Duke has really struggled defensively since returning from its short-term break, and that should make it rather difficult to win against Louisville.
The Cardinals are the perfect team to take advantage of the Blue Devils’ weaknesses, as Carlik Jones and David Johnson make up one of the best backcourts in the ACC. Jones is a potent scorer that should see a ton of success against Duke, and Johnson is a Swiss Army knife that oozes intensity. Johnson won’t take kindly to the Cardinals losing their last two games, so look for him to come out with a lot of energy in this one. Both are good at shooting from the perimeter—and there will be plenty of good looks to be had in this one.
For what it’s worth, the Cardinals are also 11-5 ATS after back-to-back games with 12 or fewer assists under Chris Mack. Look for Louisville to get back to sharing the basketball in this game, which should help the team get back on track.
PREDICTION: Louisville -2 (-110)
Over/Under Pick
The Over has hit in each of Duke’s last four games and the same actually goes for Louisville. The reality is that both of these teams are rather weak defensively this season, especially compared to last year, when the Blue Devils were 12th in the nation in adjusted defensive efficiency and the Cardinals were 30th.
When these teams met in January 2020, Louisville earned a 79-73 victory—easily going Over the 138.5-point total. And it shouldn’t be surprising if these programs combine for a ton of points again tonight.
In fact, Louisville hasn’t had a game finish below this total since January 2, and Duke hasn’t had one since December 16, which was before the team took a break from play.
PREDICTION: Over 141 (-110)
Duke vs Louisville Betting Card
- Louisville -2 (-110)
- Over 141 (-110)
Did you know that if you parlayed today’s NCAA Duke vs. Louisville picks, you could win $26.45 on a $10 bet?
Use our NCAA parlay calculator to create your own parlays and see their potential payouts.
Where Can I Bet on College Basketball?
You can bet on college basketball odds at every online and casino sportsbooks, including NCAA basketball point spreads, Over/Under totals, derivative bets and even prop plays as well. Head over to our best-suggested sportsbooks for the top spots to bet on college basketball odds in your area.
