Clemson vs BYU Prediction, Picks & Odds for Tonight's College Basketball Game

Krest's prediction: Tigers show plenty of teeth.

Shawn Krest - Betting Analyst at Covers.com
Shawn Krest • Betting Analyst
Dec 9, 2025 • 13:19 ET • 4 min read

NCAAB

Match starts: 4 hrs
BYU
48 %
CLEM
52 %
EXPERT PICK - SPREAD
Clemson +5.5 (-110) Clemson +5.5 (-110)
Read Analysis
Clemson Tigers forward RJ Godfrey (0) and Clemson Tigers forward Jake Wahlin (10) prepare for an inbounds play.
Photo By - Imagn Images. Clemson Tigers forward RJ Godfrey (0) and Clemson Tigers forward Jake Wahlin (10) prepare for an inbounds play.

The No. 10 BYU Cougars and Clemson Tigers meet tonight at Madison Square Garden in the Jimmy V Classic. 

BYU has one of the nation’s top freshmen anchoring a strong starting lineup, but my Clemson vs. BYU predictions believe the Tigers' incredible depth will play a huge role tonight. 

Find out why in my college basketball picks for Tuesday, December 9.

Clemson vs BYU prediction

Clemson vs BYU best bet: Clemson +5.5 (-110)

AJ Dybantsa has lived up to the hype so far. The No. 2 freshman in the signing class and a projected top 3 pick in the NBA Draft, Dybantsa is averaging 19.4 points and 6.3 rebounds, leading BYU in both categories. 

The Cougars aren’t a one-man show. Richie Saunders (18.9 and 5.8) and Robert Wright III (16.9 and 6.3 assists) give BYU three outstanding scoring options. 

BYU falls off after that. In the Cougars’ loss to UConn, only one other player scored more than four points. Against Villanova and Miami, no one else reached double figures. 

The BYU starting lineup has played nearly two-thirds of the time so far this season, and scored 81% of the team’s points, with the Big Three responsible for 65%. 

Normally, that wouldn’t be a major problem. Plenty of successful teams lean on three options. However, it doesn’t match up well with Clemson. The Tigers go 10 deep, with starters playing 56% of available minutes. That’s 10 percentage points more playing time for the bench than BYU.

The starters only score 56% of Clemson’s points, as well. Eight Clemson players score more than BYU’s starting center, Keba Keita. 

BYU is making its third trip to the East Coast in three weeks. The previous two trips featured a straight-up loss to UConn and an ATS loss to Dayton. The travel-weary Cougars could be vulnerable and wear down against a Clemson squad that keeps finding fresh bodies to sub in. 

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Clemson vs BYU same-game parlay

Clemson plays at the No. 296-ranked pace in the nation, but that’s already baked into the over/under cutoff. This will be the second-lowest total BYU has faced this season. Against top opponents, both teams have been hitting the gas.

BYU went over against UConn and Wisconsin, putting up totals of 168 and 170. Clemson has gone over against all four power conference opponents its faced including 191 against Georgia (in OT) and 174 against Alabama. 

Saunders scored 26 against Wisconsin, but even with that, he’s averaging just 16.5 points against power conference foes. He’s BYU’s top outside threat, and Clemson has the No. 23 perimeter defense in the country, so he’ll be a target. 

Clemson vs BYU SGP

  • Clemson +5.5
  • Over 151
  • Richie Saunders Under 17.5 points

Our beyond the arc SGP: It's showtime

Dybantsa has topped 20 points three times this season: in Las Vegas, and at the home arenas of the Celtics and Jazz. He’ll be playing at the world’s most famous arena tonight and will be ready to shine. 

Clemson vs BYU SGP

  • Clemson +5.5
  • Over 151
  • Richie Saunders Under 17.5 points
  • AJ Dybantsa Over 20.5 points

Clemson vs BYU odds

  • Spread: Clemson +5.5 | BYU -5.5
  • Moneyline: Clemson +205 | BYU -250
  • Over/Under: Over 151 | Under 151

Clemson vs BYU betting trend to know

Clemson has hit the Game Total Over in 19 of their last 33 games. Find more college basketball betting trends for Clemson vs. BYU.

How to watch Clemson vs BYU

Location Madison Square Garden, New York, NY
Date Tuesday, December 9, 2025
Tip-off 6:30 p.m. ET
TV ESPN

Clemson vs BYU key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Shawn Krest
Betting Analyst

Since quitting his job as bank assistant vice-president in 2000, Shawn has covered Final Fours, Super Bowls, World Series games and title fights in boxing and UFC. His work has appeared on ESPN, MLB.com, Sports Illustrated and dozens of other outlets. His book, Baseball Meat Market was published in 2018. He lives in North Carolina with his dog Toby, eight turtles, and wife.

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