The White Sox still have something to play for on the penultimate day of the MLB regular season. That’s why my Rockies vs. White Sox predictions have the South Siders getting the win as they chase a division title and a first-round bye.
Read on for my free MLB picks for Saturday, Sept. 26.
Who will win Rockies vs White Sox today: White Sox -1.5
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The Chicago White Sox moneyline is too expensive, although if it drops to the low 60s, I’d go with Chicago straight-up.
The Sox are a game behind AL Central-leading Cleveland and hold the tiebreaker. If they can make up one game in two days, they not only get the division title, but they’d be the second seed in the American League and get a bye through the first round of the playoffs.
They’re pushing hard, winning five of six, all by multiple runs. Meanwhile, the Colorado Rockies have dropped five straight by an average of 3.7 runs.
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Rockies vs White Sox Over/Under pick: Over 8.5
The Rockies’ Jose Quintana is making just his second start since May 24. The 37-year-old southpaw has missed most of the season with elbow trouble, and Quintana’s fastball velocity is in the third percentile in MLB.
Chicago hits lefties better than righties, with an OPS 29 points higher and OPS+ of 10% over league average, compared to below average against righties. They also homer 10% more often against left-handers.
Chicago has scored five or more in six of the last 10 and has gone Over seven times. Colorado has allowed 5+ in its last four.
Chicago starter Davis Martin has been pitching well, but he has a fastball that's been hit hard, and Colorado’s Kyle Karros is MLB’s eighth-best hitter against the four-seamer.
COVERS INTEL: Davis Martin is in the fourth percentile in hard-hit rate allowed and 11th percentile in average exit velocity. His fastball is in the bottom third in baseball in velocity, and batters are hitting .267 against it and .298 against the sinker. Both were in the .220s last season.Rockies vs White Sox home run prediction: Miguel Vargas
Miguel Vargas has been Chicago’s hottest power hitter lately, even after Munetaka Murakami went deep twice on Friday.
Vargas is hitting .364 with 1.199 OPS and 243 OPS+ over the last week and .300/.910/154 over the last two. He also hits left-handers much better, with a 160 OPS+ and a homer every 17 at-bats against southpaws, compared to 123 and every 23 against righties.
- ML/RL picks: 34-41, -0.69 units
- Over/Under picks: 46-24, +10.62 units
Rockies vs White Sox weather
The weather will be mild in Chicago, coming down from a high of 64 degrees by the time the game starts. There’s almost no chance of rain.
Rockies vs White Sox odds
- Moneyline: Rockies 32% | White Sox 68%
- Run line: Rockies +1.5 | White Sox -1.5
- Over/Under: Over 7.5 | Under 7.5
Rockies vs White Sox trend
The White Sox have covered the run line in 28 of their last 50 games at home (+7.80 Units / 12% ROI). Find more MLB betting trends for Rockies vs. White Sox.
How to watch Rockies vs White Sox and game info
| Location | Rate Field, Chicago, IL |
| Date | Saturday, Sept. 26, 2026 |
| First pitch | 7:10 p.m. ET |
| TV | Rockies.TV, Chicago Sports Network |
| Rockies starting pitcher | Jose Quintana (2-3, 5.40 ERA) |
| White Sox starting pitcher | Davis Martin (9-7, 3.84 ERA) |
Rockies vs White Sox latest injuries
Odds are correct at the time of publishing and are subject to change.
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