Padres vs Brewers Prediction, Picks & Odds for Today’s MLB Game

With both clubs having cold stretches at the plate, our expert MLB predictions are expecting a low-scoring game in Milwaukee.

Ryan Gilbert - Contributor at Covers.com
Ryan Gilbert • Betting Analyst
Jun 7, 2025 • 11:02 ET • 4 min read
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This article contains predictions for an old game!

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Jose Quintana of the Milwaukee Brewers
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The Milwaukee Brewers host the San Diego Padres on Saturday night in the middle of a three-game set.

San Diego won the series opener 2-0 on Friday night, and my Padres vs. Brewers prediction expects another low-scoring game in the best MLB picks on Saturday, June 7.

Padres vs Brewers prediction

My Padres vs Brewers best bet: Under 8.5 (-105 at BetMGM)

It's a matchup between two of the best Under teams in the league with the Milwaukee Brewers and San Diego Padres facing off. The Under is 35-25 for San Diego and 37-24 for the Brew Crew.

Both squads have also had some cold stretches with the bat as of late.

The Padres have a total of 22 runs in their last eight games, with a high of six in a contest, and the Brewers have been held to three runs or fewer in three of their previous four games. That includes the shutout at the hands of Randy Vazquez and the Friars' bullpen on Friday night.

That's not too surprising given the fact that the Brewers' bullpen has the third-best ERA in the league.

Starting on the mound will be a crafty veteran in Jose Quintana for Milwaukee and Stephen Kolek, who is enjoying a nice breakout season as a starter, for San Diego.

Quintana is 4-1 with a 2.77 ERA and 1.28 WHIP in seven starts this season. He's held the opposition to two earned runs or fewer in six of those outings.

The Padres turned Kolek into a starting pitcher after being used out of the bullpen last season. The 28-year-old right-hander is 3-1 with a 3.47 ERA and 1.23 WHIP in six starts. He settled down last start with 5.2 shutout innings against the Giants after allowing multiple ER in his three previous outings.

Neither team is scoring too much right now and we have competent arms on both sides. Look for these teams’ Under trends to continue on Saturday.

Padres vs Brewers same-game parlay (SGP)

Under 8.5

Jose Quintana 2+ walks allowed

Brewers ML

The Padres have been a few games better than the Brewers this season, but that changes based on the home/road splits. Milwaukee is 18-11 at home while San Diego is 16-16 on the road (20-10 at home). Look for Milwaukee to get back to its winning ways following a shutout loss.

Jose Quintana has allowed multiple free passes in five of his last six starts and 21 of 31 games last season -- including both matchups against the Padres. Adding this contrarian leg increases the parlay by three dollars, from +226 to +529.

Padres vs Brewers odds

Padres vs Brewers live odds

Padres vs Brewers opening odds

  • Moneyline: San Diego (-105) | Milwaukee (-115)
  • Run line: San Diego -1.5 (+155) | Milwaukee +1.5 (-190)
  • Over/Under: Over 8.5 (-115) | Under 8.5 (-105)

Padres vs Brewers trend

The Under is 37-14 in Milwaukee Brewers games this season. Find more MLB trends for Padres vs. Brewers. Find more MLB betting trends for Padres vs. Brewers.

How to watch Padres vs Brewers and game info

Location American Family Field, Milwaukee, WI
Date Saturday, 6-7-2025
First pitch 7:35 p.m. ET
TV FOX
Padres starting pitcher Stephen Kolek
(3-1, 3.47 ERA)
Brewers starting pitcher Jose Quintana
(4-1, 2.77 ERA)

Padres vs Brewers latest injuries

Padres vs Brewers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Ryan Gilbert - Covers
Betting Analyst

Ryan Gilbert brings the passion and pain of being a Philadelphia sports fan. After graduating from Monmouth University with a finance degree, he now uses his statistical background to find inefficiencies in betting markets. With past stops at NHL.com, NBC Sports, and currently at Covers, Ryan's hot picks blend well with the cold ice of a hockey rink.

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