The red-hot Atlanta Braves will be looking to keep it rolling tonight against the San Diego Padres as -137 home favorites.
My Padres vs Braves predictions expect Atlanta to take advantage of the struggling Walker Buehler.
Read more in my MLB picks for Tuesday, July 21.
Who will win Padres vs Braves today: Braves (-137)
The Atlanta Braves send Reynaldo Lopez to the mound tonight, and he's in great form. The righty has posted a 3.34 FIP across his last five appearances while allowing just 0.86 HR/9.
As for the San Diego Padres, they counter with Walker Buehler, who has hit a tough spell. The veteran owns a 9.10 FIP in his last five outings while surrendering 3.86 HR/9.
Those are dangerous numbers against a Braves offense carrying a .298 ISO and 171 wRC+ in their last four games.
Expect them to stay hot against Buehler.
I'll play this pick to -150.

Padres vs Braves Over/Under pick: Over 9.5 runs (+114)
While I do expect Lopez to throw the ball well, he’s also up against a scorching-hot Padres offense. San Diego has posted a 147 wRC+ over its last four games to go along with a .259 ISO.
Both teams are swinging it well, and while each bullpen has been respectable lately, it’s hard to overlook the offensive consistency and power output. The Padres’ hard-hit rate is also just below 50% during that span.
Atlanta gives this Over another clear path, especially against Buehler, who has struggled to limit hard contact.
I’ll play this pick to -120.
- ML/RL bets: 35-38, -7.20 units
- Over/Under bets: 41-30, +5.01 units
Padres vs Braves weather
Padres vs Braves odds
- Moneyline: Padres +127 | Braves -133
- Run line: Padres +1.5 (-156) | Braves -1.5 (+150)
- Over/Under: Over 9.5 (+117) | Under 9.5 (-122)
Padres vs Braves trend
The Atlanta Braves have hit the team total Over in 11 of their last 14 home games (+7.50 Units / 45% ROI). Find more MLB betting trends for Padres vs. Braves.
How to watch Padres vs Braves and game info
| Location | Truist Park, Atlanta, GA |
| Date | Tuesday, July 21, 2026 |
| First pitch | 7:15 p.m. ET |
| TV | Padres.TV, BravesVsn |
| Padres starting pitcher | Walker Buehler (5-5, 5.36 ERA) |
| Braves starting pitcher | Reynaldo Lopez (4-2, 3.50 ERA) |
Padres vs Braves latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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