The Chicago Cubs and St. Louis Cardinals play the rubber game of their three-game weekend series on Sunday Night Baseball.
Despite earning a split in the first two games, the series has been rough on the Cardinals’ bullpen, and they need a big night from starter Matthew Liberatore. For the Cubs, PCA and Michael Busch will look to continue their hot streaks.
Check out my full Cubs vs. Cardinals predictions and MLB picks below.
Cubs vs Cardinals props for May 31
| Pick | Odds |
|---|---|
| -110 | |
| +210 | |
| +710 |

Cubs vs Cardinals player prop picks
Matthew Liberatore Over 15.5 outs (-110)
This is less an endorsement of Matthew Liberatore and more an indication of the rough state of this St. Louis Cardinals bullpen. The last two starters have lasted a total of 7 1/3 innings, leaving eight St. Louis relievers to pitch 10 2/3 innings, throwing 164 pitches and giving up six runs.
Even if Liberatore is struggling, he’ll probably have to wear it and pitch into the sixth just to give the pen a rest. He’s done it twice this month and four times this season, and Liberatore is coming off a 101-pitch effort where he struck out a career-high 10. He’s ready for the workhorse role.
Michael Busch Over 2.5 hits + runs + RBI (+210)
Michael Busch has been the best-hitting first baseman in MLB for May and will add to his totals on the month’s final day. He’s hitting 73% better than the league average for the month and has a .955 OPS.
He has six runs, nine hits, and eight RBI over the last week, and he has four hits and four RBI in the first two games of the series. Busch homered and had a two-hit game in his only previous time facing Liberatore.
Pete Crow-Armstrong to hit a home run (+700)
Pete Crow-Armstrong had a big game on Saturday, going 4-for-5, homering, and keeping up a running taunting dialogue with the St. Louis fans. Once he’s fired up, he generally stays that way. Of his 48 career home runs, 12 have come within a day of a previous blast.
PCA has a five-game hitting streak and is hitting .364 with a .917 OPS over that stretch. His seven homers against the Cardinals are the most against any team, and his three homers at Busch match his highest in any visiting park.
How to watch Cubs vs Cardinals and game info
| Location | Busch Stadium, St. Louis, MO |
| Date | Sunday, May 31, 2026 |
| First pitch | 7:20 p.m. ET |
| TV | NBC |
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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