The New York Yankees picked up a shutout victory Tuesday night, and they're -150 favorites to take today's rubber match.
With St. Louis spiralling offensively, my Cardinals vs. Yankees predictions see value in backing the home team to pick up another low-scoring win.
Let's break it all down with my MLB picks on Wednesday, Aug. 5.
Who will win Cardinals vs Yankees today: New York Yankees (-155)
Will Warren's indicators (3.58 xFIP, 4.06 SIERA) suggest he has pitched better than his results (6.05 ERA) over the last month, and this is a good spot for the tide to turn.
The St. Louis Cardinals have struggled mightily to produce against righties, ranking dead last in wOBA and OPS during that span.
The New York Yankees have the better and more in-form bullpen, so there won’t be any soft spots where the Cardinals have an advantage at the plate.
I’d play the Yankees to -160.
COVERS INTEL: Warren's much-improved 24.1% fly-ball rate over the past month gives him a better chance of keeping the ball in the park.
Cardinals vs Yankees Over/Under pick: Under 8.5 (+100)
Warren’s Achilles' heel is conceding power, and that shouldn’t be much of an issue against the Cardinals.
They own a putrid .090 ISO and sit 29th in HR/FB against right-handed pitching over the last 30 days.
While the Yankees have hit for some power, Andre Pallante’s 96th-percentile ground-ball rate will help take that out of the equation.
The power has also come at a high cost in terms of strikeouts, with no team punching out at a higher clip the past month.
I see a ton of value on this Under, and would bet it to -130.
- ML/RL bets: 70-63, -7.20 units
- Over/Under bets: 73-54-4, +10.24 units
Cardinals vs Yankees weather
The forecast calls for temperatures hovering around 80, with winds blowing West. Small bump to the bats.
Cardinals vs Yankees odds
- Moneyline: Cardinals +135 | Yankees -155
- Run line: Cardinals +1.5 (-150) | Yankees -1.5 (+130)
- Over/Under: Over 8.5 (-120) | Under 8.5 (+100)
Cardinals vs Yankees trend
New York has hit the Game Total Under in 25 of the last 40 games (+8.70 units, 20% ROI). Find more MLB betting trends for Cardinals vs. Yankees.
How to watch Cardinals vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Wednesday, August 5, 2026 |
| First pitch | 7:05 p.m. ET |
| TV | Prime Video |
| Cardinals starting pitcher | Andre Pallante (11-6, 3.72 ERA) |
| Yankees starting pitcher | Will Warren (8-5, 4.14 ERA) |
Cardinals vs Yankees latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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