The Houston Astros were able to grind out a 2-1 win in the series opener Thursday night.
While Detroit is slightly favored to even things up Friday, my Astros vs. Tigers predictions and MLB picks see value in backing the road team.
Who will win Astros vs Tigers today: Houston Astros (+100)
Spencer Arrighetti was borderline untouchable the first couple of months despite rocky numbers beneath the surface.
The pendulum has swung a little too far the other way over the last month, with Arrighetti posting a 5.79 ERA despite a respectable 3.89 FIP.
He is poised to get back on track against the Detroit Tigers, who sit 26th in wOBA vs. righties the past two weeks.
The Houston Astros rank 16th in wOBA and eighth in ISO during the same period. They should cause trouble for Keider Montero, whose 4.68 xFIP signals regression is coming.
Back Houston to -115.

Astros vs Tigers Over/Under pick: Under 9.0 (-115)
The Astros have struggled to deliver ceiling-level offensive performances, scoring four runs or fewer in eight of their last 10 games.
It’s been a similar story for the Tigers. They plated just 28 runs over the last nine games (3.11 per), eight of which came Under the pre-game total.
While Arrighetti and Montero have both pitched worse than their season outputs suggest, these are not the offenses to truly take advantage.
The bullpens are also in great shape, and each team sits Top-3 in bullpen FIP during the month of June.
Bet the Under to -125.
- ML/RL bets: 42-31, +2.2 units
- Over/Under bets: 38-31-4, +3.24 units
Astros vs Tigers weather
Temperatures in the high 60s are expected with slight winds blowing inwards. Small boost to the pitchers.
Astros vs Tigers odds
- Moneyline: Astros -105 | Tigers -115
- Run line: Astros +1.5 (-210) | Tigers -1.5 (+170)
- Over/Under: Over 9.0 (-105) | Under 9.0 (-115)
Astros vs Tigers trend
Houston has won 12 of the last 18 away games (+7.50 units, 40% ROI). Find more MLB betting trends for Astros vs. Tigers.
How to watch Astros vs Tigers and game info
| Location | Comerica Park, Detroit, MI |
| Date | Friday, June 26, 2026 |
| First pitch | 6:40 p.m. ET |
| TV | SCHN, DSN |
| Astros starting pitcher | Spencer Arrighetti (7-3, 3.31 ERA) |
| Tigers starting pitcher | Keider Montero (3-5, 3.68 ERA) |
Astros vs Tigers latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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