The regular season comes to an end with Week 18 NFL odds on the board. It's a grand finale, with many teams looking to lock up a playoff spot at the 11th hour.
As we look into our crystal ball, key games like Saints at Buccaneers, Bears at Packers, Browns at Ravens, or even Texas at Titans could all play vital roles in determining Division winners, or wild-card spots.
Here's a look at the NFL Week 18 opening odds.
NFL Week 18 odds, lines, and spreads
These are the live NFL odds for Week 18, highlighting the best odds available from regulated sportsbooks within your area.
| Game | Time (ET) | Spread | Total |
|---|---|---|---|
| Browns at Ravens | Sunday, 1:00 p.m. | Ravens -4.5 | 44.5 |
| Giants at Eagles | Sunday, 1:00 p.m. | Eagles -5.5 | 43 |
| Bears at Packers | Sunday, 1:00 p.m. | Packers -3 | 46 |
| Panthers at Falcons | Sunday, 1:00 p.m. | Falcons -6.5 | 45.5 |
| Saints at Buccaneers | Sunday, 1:00 p.m. | Buccaneers -2.5 | 43 |
| Commanders at Cowboys | Sunday, 1:00 p.m. | Cowboys -5.5 | 46.5 |
| Chiefs at Broncos | Sunday, 1:00 p.m. | Chiefs -4 | 42.5 |
| Jaguars at Colts | Sunday, 1:00 p.m. | Colts -2 | 46.5 |
| 49ers at Cardinals | Sunday, 1:00 p.m. | 49ers -4 | 43 |
| Vikings at Lions | Sunday, 1:00 p.m. | Lions -5.5 | 47 |
| Texans at Titans | Sunday, 1:00 p.m. | Texans -3 | 45 |
| Dolphins at Jets | Sunday, 1:00 p.m. | Jets -3 | 45 |
| Bills at Patriots | Sunday, 1:00 p.m. | Bills -3.5 | 44.5 |
| Seahawks at Rams | Sunday, 1:00 p.m. | Rams -5.5 | 47 |
| Bengals at Steelers | Sunday, 1:00 p.m. | Bengals -1 | 43.5 |
| Chargers at Raiders | Sunday, 1:00 p.m. | Chargers -1 | 43.5 |
Odds courtesy of DraftKings on 5-17-24
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