Atlanta @ San Francisco Game Overview

Atlanta (3-2) has picked up consecutive wins against reigning conference finalists with home victories over the Washington Commanders and Buffalo Bills. For a team looking to snap a seven-year postseason drought, it's the Falcons' defense that has spearheaded the impressive two-week stretch.

Led by first-year coordinator Jeff Ulbrich, Atlanta allows a league-low 253.4 yards per game and its 14 sacks are almost halfway to last season's total of 31, which ranked worst in the NFC.

Last time out, the Falcons held 2024 MVP Josh Allen to 180 passing yards while intercepting him twice and sacking him four times in a 24-14 win Monday night. Atlanta will face backup Mac Jones at quarterback this week, but with Christian McCaffrey in the San Francisco backfield, Falcons coach Raheem Morris knows his defense will have to continue to play at a high level.

"You know you've got to be ready for a tough, downhill run game," Morris said of the 49ers. "I know it hasn't been going up to this point for those guys, but we know how quickly that can change. They've been doing a great job being efficient in their pass game; they have two quarterbacks that have played well this year. ... They've got a lot of really good football players, starting with Christian McCaffrey, obviously the most used player in football."

Learning to play complementary football, Atlanta also boasts the leader in yards from scrimmage in running back Bijan Robinson, whose 822 total yards (484 rushing, 338 receiving) sit atop the NFL despite him playing in just five games. The next 11 players on the list -- including McCaffrey (780 yards) -- have played in six games.

Robinson, who was named NFC Offensive Player of the Week after piling up 238 yards from scrimmage against the Bills, appreciates the momentous run he's been on, but realizes the team is only as good as its next win.

"We've got to put (the win over Buffalo) to the side super fast, because the 49ers just came off of a loss and that's a great team," Robinson said. "They're going to come in ready this week, so that should be the focus at hand. As soon as we start getting into the praise from social media, then our focus is off."

Atlanta ruled out five players -- edge rusher Jalon Walker (groin), cornerback Clark Phillips III (triceps/illness), defensive back Billy Bowman Jr. (hamstring), receiver Ray-Ray McCloud (not injury related) and safety Jordan Fuller (knee). Receiver Darnell Mooney (hamstring) sat out practice on Friday and is questionable as is tackle Jake Matthews (ankle).

Defensive lineman Ta'Quon Graham (calf), who was listed as questionable, was activated off injured reserve on Saturday.

Prior to the 49ers' 30-19 loss to the Tampa Bay Buccaneers on Sunday, each of their first five games were decided by five points or fewer. San Francisco (4-2) had its good fortune halted in Week 6, as it lost its leading tackler Fred Warner to a season-ending dislocated and fractured ankle. Compiled with five-time Pro Bowl defensive end Nick Bosa's torn ACL, the 49ers' defense could be reeling against a confident Atlanta team.

"Everyone knows how special Fred is to this team, both as a player and a person," San Francisco head coach Kyle Shanahan said.

As injury-marred as the 49ers' defense is, the offense will get a major boost. Veteran tight end George Kittle will play for the first time since sustaining a hamstring injury in the season opener against the Seattle Seahawks. Kittle was limited in his first practices back on Wednesday and Thursday but worked in full on Friday and was activated off IR on Saturday.

"George has rehabbed really well," Shanahan told reporters on Friday. "He came back 100%, had a good week of practice, and we'll space it out throughout the game, but there's no pitch count."

At quarterback, Jones has filled in admirably for the injured Brock Purdy (toe), throwing for 1,252 yards and six touchdowns in four games, but he has been hampered with both knee and oblique injuries. He returned to full participation on Thursday and Friday and does not have an injury designation.

Purdy, receiver Ricky Pearsall (knee) and defensive lineman Yetur Gross-Matos (knee/hamstring) were ruled out on Friday. Defensive lineman Kevin Givens (pectoral) and cornerbacks Renardo Green (neck) and Upton Stout (shoulder) are questionable. Givens was activated off IR on Saturday.

Shanahan knows the offense will have its hands full with the upstart Atlanta defense.

"I see a bunch of good guys. They're all very active," Shanahan said of the Falcons' defensive unit. "Every one of them has the ability to rush the quarterback. I think their scheme and how they're coached is very good. They're playing the right way and they're talented."

--Field Level Media