Lions vs Bills Prediction, Picks, Prop Bets For September 17, 2026

DET vs BUF Picks

NFL Picks

There are no Expert or Computer Picks for this matchup at the moment.

NFL

05/15/2026 08:58 ET

NFL

05/15/2026 08:11 ET

NFL

05/15/2026 02:05 ET

NFL

05/14/2026 10:46 ET

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There are no projections available for this matchup at the moment.

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There are no User Picks for this match up at the moment. Visit our Team Leaders to see all User picks.

Rank	Leader	L10	Units
1	jstoltey	8-2-0	+6850
2	PaPe454	8-2-0	+6500
3	Mexicali72	8-2-0	+6350
4	darkhorse12	8-2-0	+5700
5	Cheezer69	10-0-0	+5650
6	gargoyle127	6-4-0	+5600
7	whooped	7-3-0	+5450
8	Bigfoot76	8-2-0	+5450
9	livelywee55	8-2-0	+5380
10	CAlex6977	8-2-0	+5350
All Lions Money Leaders

Rank	Leader	L10	Units
1	charro23	6-4-0	+8220
2	midsro49	7-3-0	+5900
3	OOOPA LOOPA	9-1-0	+5650
4	deweyay9	7-3-0	+5500
5	slipknot1485	9-1-0	+5400
6	dcrunk022	8-2-0	+5350
7	sake	8-2-0	+5350
8	automatic48	7-3-0	+5300
9	johnnyjbd24	6-4-0	+5200
10	oneg	8-2-0	+5150
All Bills Money Leaders