MLB Picks

Get free expert and computer MLB picks for every game on April 22, 2026. With over 25 years of betting experience, our analysts and predictive models help you find the best value.

Houston Astros logo HOU @ Cleveland Guardians logo CLE Wed, Apr 22 • 1:10 PM ET
10 Computer Picks
Total Bases
Yordan Alvarez logo
Yordan Alvarez o1.5 Total Bases (+105)
Projection 2.06
Best Odds
Pick made: 30 minutes ago
EV Model Rating
Star rating: 4 out of 5
According to the leading projection system (THE BAT X), Yordan Alvarez ranks as the 2nd-best batter in the league.. Yordan Alvarez is projected to hit 2nd in the batting order today.. The #3 field in baseball for boosting base hits to LHB, per the leading projection system (THE BAT), is Progressive Field.. Built 673 feet above sea level, Progressive Field has the 7th-highest elevation among all parks, which tends to lead to higher offensive output.. Humid weather has a small yet noteworthy link with more offense (and fewer whiffs), and the weather report calls for the most humidity on the slate at 84%.
Total Bases
Kyle Manzardo logo
Kyle Manzardo u1.5 Total Bases (-235)
Projection 0.68
Best Odds
Pick made: 30 minutes ago
EV Model Rating
Star rating: 3 out of 5
Kyle Manzardo has been pinch hit for 20% of the time when starting against a righty hurler this year.. In Major League Baseball, the 4th-tallest fences are at Progressive Field.. Kyle Manzardo has taken a step back with his Barrel% lately; his 10.8% seasonal rate has decreased to 0% over the past 7 days.. With a .219 Expected Batting Average (an advanced metric created by the leading projection system (THE BAT X) utilizing Statcast data) since the start of last season , Kyle Manzardo finds himself in the 13th percentile.. Kyle Manzardo has put up a .273 BABIP since the start of last season, ranking in the 23rd percentile.
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Cincinnati Reds logo CIN @ Tampa Bay Rays logo TB Wed, Apr 22 • 1:10 PM ET
10 Computer Picks
Total Hits
Will Benson logo
Will Benson u0.5 Total Hits (+110)
Projection 0.54
Best Odds
Pick made: 2 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Will Benson in the 15th percentile as it relates to his batting average talent.. Will Benson is penciled in 8th in the batting order in this matchup.. The #4 ballpark in the game for suppressing BABIP to LHB, via the leading projection system (THE BAT), is Tropicana Field.. In today's game, Will Benson is at a disadvantage facing the league's 9th-deepest CF center field fences given that he hits his flyballs towards center field at a 38.4% rate (87th percentile).. Playing on the road typically lessens batter stats in all categories due to the lack of home field advantage, which should be the case for Will Benson in today's matchup.
Total Hits
Jonny DeLuca logo
Jonny DeLuca u0.5 Total Hits (+140)
Projection 0.73
Best Odds
Pick made: 2 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Jonny DeLuca in the 18th percentile when assessing his BABIP talent.. The leading projection system (THE BAT) profiles Tropicana Field as the 4th-worst venue in the game for righty BABIP.. Jonny DeLuca's exit velocity on flyballs has fallen off lately; his 86.9-mph seasonal EV has fallen to 75.2-mph in the last 7 days.. Compared to his seasonal angle of 11.7°, Jonny DeLuca has produced a noticeably lower launch angle (5.8°) over the last two weeks.. Based on Statcast data, the leading projection system (THE BAT X)'s version of Expected wOBA (.244) provides evidence that Jonny DeLuca has been lucky since the start of last season with his .355 actual wOBA.
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Baltimore Orioles logo BAL @ Kansas City Royals logo KC Wed, Apr 22 • 2:10 PM ET
3 Expert Picks 10 Computer Picks
Total
Baltimore Orioles logo Kansas City Royals logo u9.5 (-126)
Best Odds
Pick made: 6 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

Wacha may be outperforming his metrics, but his 23.5% strikeout rate and 33% chase rate are legitimate, and Baltimore's lineup punches out 25% of the time against right-handers. 

Kansas City's bullpen may be a disaster, but they won't be tested much if Wacha deals deep into the game. Kansas City's hacky lineup will swing early and often against Bassitt, which should help the struggling Orioles starter.

With two pitchers doing just enough against two aggressive lineups, runs might be hard to come by. Take the Under.

Moneyline
Baltimore Orioles logo BAL (+115)
Best Odds
Pick made: 6 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

The Baltimore Orioles lineup is already rolling, scoring 12 runs in this series, and this is not a soft landing spot. The Orioles also hold a clear bullpen edge, with a reliable relief group compared to the Kansas City Royals' struggles. 

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Toronto Blue Jays logo TOR @ Los Angeles Angels logo LAA Wed, Apr 22 • 3:07 PM ET
2 Expert Picks 10 Computer Picks
Total Home Runs
Daulton Varsho logo Daulton Varsho o0.5 Total Home Runs (+510)
Best Odds
Pick made: 3 hours ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Daulton Varsho brings a lot of pop from the left side of the plate, and Soriano has given up a little bit more power to lefties than righties this season. Varsho does seem to see the sinker well out of the pitcher's hand, which is the most used pitch Soriano throws against lefties. The Jays outfielder owns a .438 batting average and a .688 slugging percentage against the pitch.

Total Bases
Vladimir Guerrero Jr. logo Vladimir Guerrero Jr. o1.5 Total Bases (+135)
Best Odds
Pick made: 3 hours ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Vladdy is 2-for-2 with a walk in three plate appearances against Jose Soriano, and Soriano's most-used pitch is a sinker-ball, a pitch that Guerrero owns a .444 batting average with a 55% hard-hit rate against. I’m expecting Guerrero Jr. to continue this trend as he's one of baseball’s best hitters.

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Athletics Athletics logo ATH @ Seattle Mariners logo SEA Wed, Apr 22 • 4:10 PM ET
1 Expert Pick 10 Computer Picks
Total Home Runs
Shea Langeliers logo Shea Langeliers o0.5 Total Home Runs (+440)
Best Odds
Pick made: 4 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

Let's stay indoors and bet on a bat who has already homered in two straight games in Seattle with Shea Langeliers, who has launched eight homers this year. Logan Gilbert is a flyball pitcher, which is in our favor here, and Langeliers has also seen plenty of this Seattle bullpen and took it deep last night. Ultimately, this is a play on price, and getting elite HR hitters at +EV isn't a common occurrence. The fair price is around +380. Let's back the hot stick today with great expected value. 

Total Hits
Carlos Cortes logo
Carlos Cortes u0.5 Total Hits (+135)
Projection 0.7
Best Odds
Pick made: 9 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Carlos Cortes in the 11th percentile when assessing his BABIP skill.. When starting against a right-handed starter this year, Carlos Cortes has been replaced by a pinch-hitter 47% of the time.. The leading projection system (THE BAT) profiles T-Mobile Park as the worst venue in the league for lefty batting average.. T-Mobile Park's elevation is near sea-level, one of the lowest in MLB, which generally leads to lower offensive output.. Less offense (and more strikeouts) are strongly linked with lower temperatures, and the weather report for this contest predicts the 4th-lowest temperature on the slate today at 57°.
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Milwaukee Brewers logo MIL @ Detroit Tigers logo DET Wed, Apr 22 • 6:40 PM ET
2 Expert Picks 10 Computer Picks
Total
Milwaukee Brewers logo Detroit Tigers logo o7.5 (-120)
Best Odds
Pick made: 2 hours ago
Quinn Allen image
Quinn Allen
Betting Analyst

The Brew Crew has cashed the Over in three of their last four. The Detroit Tigers have also hit the Over in runs in three straight. Both of these bullpens also have ERAs over four, so once the starters have departed, there’s lots of opportunity for runs. Plus, the Milwaukee Brewers are fourth in runs scored, and Detroit is 15th.

Moneyline
Detroit Tigers logo DET (-130)
Best Odds
Pick made: 2 hours ago
Quinn Allen image
Quinn Allen
Betting Analyst

The Detroit Tigers are 8-2 at home this season, and Casey Mize has been dominant so far, posting a 2.78 ERA. Chad Patrick has pitched well too, but his FIP isn't great, and Detroit is scoring over five runs per contest at Comerica. 

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Atlanta Braves logo ATL @ Washington Nationals logo WAS Wed, Apr 22 • 6:45 PM ET
10 Computer Picks
Total Bases
James Wood logo
James Wood o1.5 Total Bases (+125)
Projection 1.95
Best Odds
Pick made: 2 hours ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects James Wood as the best hitter in the game as it relates to his BABIP ability.. James Wood is projected to hit 1st on the lineup card in this game.. In Major League Baseball, Nationals Park's RF fences are the 9th-shallowest.. In terms of temperature and humidity, the weather report projects for the 3rd-most favorable hitting conditions of the day.. Martin Perez will have the handedness advantage over James Wood in today's matchup.
Total Bases
Michael Harris II logo
Michael Harris II o1.5 Total Bases (+130)
Projection 1.8
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Michael Harris II in the 93rd percentile when estimating his batting average talent.. In Major League Baseball, Nationals Park's RF fences are the 9th-shallowest.. In terms of temperature and humidity, the weather report projects for the 3rd-most favorable hitting conditions of the day.. Batting from the opposite that Zack Littell throws from, Michael Harris II will have the upper hand today.. Michael Harris II has made sizeable gains with his Barrel%, bettering his 9.1% rate last season to 17% this season.
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New York Yankees logo NYY @ Boston Red Sox logo BOS Wed, Apr 22 • 6:45 PM ET
2 Expert Picks 10 Computer Picks
Total
New York Yankees logo Boston Red Sox logo u7.5 (+100)
Best Odds
Pick made: 2 hours ago
Chris Hatfield image
Chris Hatfield
Betting Analyst

Suarez's groundball rate of 46% plays well against the various weak spots in the Yankees' lineups, which likely means we don’t see many big innings. Ryan McMahon, Paul Goldschmidt, and Jose Caballero all have started this season with around a 50% groundball rate, which is particularly problematic in this spot. On the other side, the Red Sox's weak contact against lefties should show up here. 

Moneyline
New York Yankees logo NYY (-131)
Best Odds
Pick made: 2 hours ago
Chris Hatfield image
Chris Hatfield
Betting Analyst

Boston's lineup compounds the issues Fried presents: the Red Sox have a 50% groundball rate and just 29% hard contact against left-handed pitching this season, the lowest hard-hit rate vs LHP in the AL East. Fried does not need to strike hitters out to dominate. He induces the weakest contact in the game, and Boston is already predisposed to weak contact against lefties. Red Sox lefty Ranger Suarez's 4.42 expected ERA tells you his 3.22 surface ERA is living on borrowed time, and the Yankees hit lefties quite hard, posting the fourth-highest hard-hit rate against southpaws this season.

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Minnesota Twins logo MIN @ New York Mets logo NYM Wed, Apr 22 • 7:10 PM ET
2 Expert Picks 10 Computer Picks
Total
Minnesota Twins logo New York Mets logo o7.5 (-115)
Best Odds
Pick made: 18 minutes ago
Ed Scimia image
Ed Scimia
Betting Analyst

The Mets' offense showed vague signs of life last night when Francisco Lindor hit a three-run homer. Minnesota eventually pushed through runs as well, and even in a game where both starting pitchers were excellent, the total of 7.5 proved too low. I expect a similar outcome tonight. The Twins are scoring 5.09 runs per game, and they’ll get into the New York bullpen, as Holmes is averaging only 5.8 innings per start.

Spread
New York Mets logo NYM -1.5 (+140)
Best Odds
Pick made: 20 minutes ago
Ed Scimia image
Ed Scimia
Betting Analyst

Juan Soto returns to the New York Mets lineup tonight, and he’s desperately needed. The Mets have scored just 13 total runs over their last eight games heading into tonight’s contest, and bringing back Soto’s .355 batting average and .412 OBP is the spark they're looking for. New York will also benefit from Minnesota calling up left-hander Connor Prielipp for his MLB debut. Prielipp posted a 4.03 ERA across 82.2 innings of minor league action in 2025. Meanwhile, Mets starter Clay Holmes sports a 1.96 ERA through four starts, and the righty should help New York pull away at Citi Field.

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Philadelphia Phillies logo PHI @ Chicago Cubs logo CHC Wed, Apr 22 • 7:40 PM ET
4 Expert Picks 10 Computer Picks
Total
Philadelphia Phillies logo Chicago Cubs logo o8.5 (+110)
Best Odds
Pick made: 2 hours ago
Todd Cordell image
Todd Cordell
Betting Analyst

Taijuan Walker has allowed 4+ runs in three of his four appearances and that is no coincidence. 

He ranks in the ninth percentile or lower in whiff rate, xERA, and xBA. He can’t miss bats and is allowing a ton of quality contact.

The Phillies have gotten 4.2 innings or less from their starter in three straight games and used five relievers yesterday, leaving their bullpen vulnerable behind him.

Matthew Boyd has allowed a sky-high 17.3% barrel rate early on and last pitched April 1st, which is less than ideal when taking on a Phillies team with real power. 

Moneyline
Chicago Cubs logo CHC (-170)
Best Odds
Pick made: 2 hours ago
Todd Cordell image
Todd Cordell
Betting Analyst

The Phillies are expected to use Kyle Backhus as an opener before turning to Taijuan Walker for a handful of innings. That’s a recipe for disaster. Backhus has allowed four runs and a couple of homers in 6 2/3 innings while Walker’s struggles have been even more alarming. He owns a 9.16 ERA, 2.04 WHIP, and has surrendered six homers in less than 19 innings of work. That has resulted in a -0.81 WPA (win probability added), the worst mark of today’s projected arms.

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Pittsburgh Pirates logo PIT @ Texas Rangers logo TEX Wed, Apr 22 • 8:05 PM ET
10 Computer Picks
Total Bases
Oneil Cruz logo
Oneil Cruz o1.5 Total Bases (+130)
Projection 1.89
Best Odds
Pick made: 1 hours ago
EV Model Rating
Star rating: 4 out of 5
Oneil Cruz projects as the 12th-best home run batter in the league, via the leading projection system (THE BAT X).. Oneil Cruz is projected to hit 1st on the lineup card in this game.. Among all major league parks, Globe Life Field has the 6th-lowest average fence height.. The Globe Life Field roof is expected to be closed today, making conditions in this match-up 6° hotter than the average outdoor game on the schedule today — favorable for offense.. Batting from the opposite that Jack Leiter throws from, Oneil Cruz will have an edge today.
Total Bases
Brandon Lowe logo
Brandon Lowe u1.5 Total Bases (-153)
Projection 0.9
Best Odds
Pick made: 26 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT) profiles Globe Life Field as the worst field in the league for run-scoring.. The 6th-deepest centerfield dimensions in the league are found in Globe Life Field.. Among every team today, the 4th-strongest infield defense is that of the Texas Rangers.. Playing on the road typically lowers batter stats across the board due to the lack of home field advantage, which ought to be the case for Brandon Lowe today.. Brandon Lowe's average exit velocity has dropped off this year; his 91-mph mark last year has fallen off to 86.2-mph.
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San Diego Padres logo SD @ Colorado Rockies logo COL Wed, Apr 22 • 8:40 PM ET
2 Expert Picks 10 Computer Picks
Spread
San Diego Padres logo SD -1.5 (+100)
Best Odds
Pick made: 4 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

Don’t let the sub-4.00 ERA from Tomoyuki Sugano fool you. He’s been one of the luckiest pitchers to start the year, carrying a 7.71 xERA vs. a 3.92 ERA. He’s getting hit hard, running a low BABIP, and stranding 88% of runners — clear regression signals. The San Diego Padres, sitting at 16-7 SU, are well-positioned to stack runs and win by multiple runs. A late comeback is unlikely with a fully available bullpen, including Mason Miller, who was rested yesterday. The fair price on the moneyline sits around -195 versus a -165 market, and the run line breakeven is closer to -130, making +100 strong value. The Rockies were just shut out last night, and I'm hoping that struggle continues into today.

Total Home Runs
Fernando Tatis Jr. logo Fernando Tatis Jr. o0.5 Total Home Runs (+400)
Best Odds
Pick made: 4 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

I had this start circled for five days. Tomoyuki Sugano owns a sub-4.00 ERA, but his xERA is closer to 8.00. He’s been wildly lucky while allowing the eighth-worst Blast Contact% among starters, and he’s also posted one of the worst HR/9 rates over the last two seasons. In short, the San Diego Padres are a great place to look for dingers on Wednesday at Coors Field, especially with poor hitting weather elsewhere. Fernando Tatis Jr. is +400 to go deep with a fair price around +330, per Covers projections powered by THE BAT. He’s the best +EV home run on the board this morning. It’s surprising he hasn’t gone deep yet, but that’s why the price is discounted. He leads the team with a 27.5% Blast Contact% rate, and it feels like a matter of time before that breaks through.

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Chicago White Sox logo CHW @ Arizona Diamondbacks logo AZ Wed, Apr 22 • 9:40 PM ET
1 Expert Pick 10 Computer Picks
Total RBIs
Munetaka Murakami logo Munetaka Murakami o0.5 Total RBIs (+150)
Best Odds
Pick made: 4 hours ago
Quinn Allen image
Quinn Allen
Betting Analyst

The slugger has eight RBI across his last four games, and he’s also gone deep in four straight appearances. Murakami cannot be stopped. He was 3-for-5 in Tuesday’s series opener against the Arizona Diamondbacks with a home run, an RBI, and three hits.

Total Bases
Colson Montgomery logo
Colson Montgomery u1.5 Total Bases (-182)
Projection 0.89
Best Odds
Pick made: 18 minutes ago
EV Model Rating
Star rating: 3 out of 5
Colson Montgomery is penciled in 6th in the lineup in this matchup, which would be a downgrade from his 75% rate of hitting in the top-half of the lineup this season.. The league's 10th-highest average fence height can be found at Chase Field.. Batting from the same side that Eduardo Rodriguez throws from, Colson Montgomery meets a tough challenge today.. Colson Montgomery pulls a lot of his flyballs (40.4% — 98th percentile) and will be challenged by MLB's 3rd-deepest RF fences in today's game.. Colson Montgomery will be at a disadvantage playing on the road in today's matchup.
View 11 Picks
Los Angeles Dodgers logo LAD @ San Francisco Giants logo SF Wed, Apr 22 • 9:45 PM ET
5 Expert Picks 10 Computer Picks
Spread
Los Angeles Dodgers logo LAD -1.5 (-125)
Best Odds
Pick made: 1 hours ago
Joe Osborne image
Joe Osborne
Senior Betting Analyst

Shohei Ohtani looks dominant early, opening the season with a 0.50 ERA and a 0.72 WHIP. That WHIP aligns strongly with a Giants lineup that’s ranked 27th in on-base % over the last two weeks. On the other side, Tyler Mahle has been obliterated in two of his last three starts and draws a Dodgers offense that excels vs right-handed pitching. Los Angeles is also 5-1 after losses this season. Expect a motivated version of the team tonight.

Strikeouts Thrown
Shohei Ohtani logo Shohei Ohtani o6.5 Strikeouts Thrown (-122)
Best Odds
Pick made: 4 hours ago
Quinn Allen image
Quinn Allen
Betting Analyst

Ohtani racked up 10 Ks in his last start against the New York Mets. While San Fran is around the middle of the pack in team strikeouts, they’re swinging and missing a lot more lately, striking out nearly 10 times per game across their previous three contests. Also, Ohtani has collected 16 Ks in 12 innings of work at home. 

View 15 Picks

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