MLS All-Stars vs Liga MX All-Stars Predictions, Picks & Odds for Today’s Friendly Match

Jason Ence - Contributor at Covers.com
Jason Ence • Betting Analyst 13+ years betting experience
Updated: Jul 29, 2026 , 08:14 AM ET • 4 min read

No Lionel Messi, no problem for the MLS All-Stars in Charlotte.

Thomas Muller Vancouver Whitecaps MLS
Photo By - Reuters Connect. Thomas Muller before a game against FC Cincinnati.

Wednesday night will see the MLS All-Stars host the Liga MX All-Stars in an exhibition match in Charlotte.

Lionel Messi has opted out of the contest for the second straight year, but there will still be plenty of firepower on display for the MLS side.

That’s why my MLS All-Stars vs. Liga MX All-Stars predictions and free betting picks are backing them to claim victory as favorites. 

MLS All-Stars vs Liga MX All-Stars predictions

Pick Price
Who will win pick: MLS All-Stars +127
Over/Under pick: Under 4.5 +117
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Who will win MLS All-Stars vs Liga MX All-Stars: MLS All-Stars (+127)

The MLS All-Star team will not have Lionel Messi or Sebastian Berhalter at their disposal. The Argentine forward is getting much-needed rest after a World Cup run, while the American midfielder completed a move on Tuesday to Middlesbrough.

As a result, the MLS side is fetching a better price than normal, and I’m here to take advantage of it.

At the end of the day, this MLS squad still has better overall talent than their Liga MX counterparts. A key reason for that is the number of withdrawals they’ve had from their side, led by Mexican starlet Gilberto Mora. 

The Liga MX side also lacks a true goalscoring threat. That’s one thing MLS won’t be without.

This MLS All-Star side can send out Thomas Muller, Petar Musa, Son Heung-min, Sam Surridge, and Hany Mukhtar, just to name a few. The number of goal creators this side has compared to Liga MX’s depleted roster is mouth-watering.

Were the Liga MX team at full strength, this would be a much more competitive match. Their defections have left them very vulnerable to a rout, and I’m backing the MLS players all day down to +100 

MLS All-Stars vs Liga MX All-Stars Over/Under pick: Under 4.5 (+117)

With that said, I’m not backing a massively high-scoring affair. 

I honestly struggle to see where the Liga MX roster is going to contribute to the inflated 4.5-goal total for this match. The forwards on their roster lack consistent productivity, and the loss of Mora robs them of their primary chance-creator.

On the flip side, Liga MX has three members of the Mexican national team that saw major minutes at the 2026 World Cup, all of whom operate primarily at the defensive end. 

Additionally, we’re likely to see plenty of substitutions in this match. That typically leads to a disruption of flow and cohesion, especially among players who aren’t familiar with playing together. 

This is the fifth time the MLS All-Star game has followed this format, and only one of those contests saw five goals scored. Liga MX fell 3-1 last year, and Mora scored their only goal. 

Expect another contest that goes south of the total, which I’m backing down to +105.

MLS All-Stars vs Liga MX All-Stars odds

MLS All-Stars  Liga MX All-Stars
+127 Moneyline +163
+376 Draw +376
Over 4.5 (-127) Total Under 4.5 (+117)

Odds courtesy of Polymarket.

How to watch MLS All-Stars vs Liga MX All-Stars

Location Bank Of America Stadium, Charlotte, NC
Date Wednesday, July 29, 2026
Time 8 p.m. ET
TV Apple TV

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Jason Ence - Covers
Betting Analyst

Jason has been hooked on football since watching Real Madrid and Manchester United in the 2003 Champions League, and has been betting on the sport for nearly 15 years. He has given soccer gambling and fantasy advice for nearly a decade, writing for sites including Rotowire, SB Nation, and The TwinSpires Edge.

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