Titans vs Patriots Week 12 Picks and Predictions: New England Hype Train Keeps Rolling

A potentially great game between the Titans and Patriots is dimmed by Tennessee's injury woes on offense. The hope around a new-look New England team, however, is bright as ever as our NFL betting picks break down.

Last Updated: Nov 26, 2021 7:34 PM ET Read Time: 5 min
Matt Judon New England Patriots NFL
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The New England Patriots will be looking for their sixth straight win (SU and ATS) Sunday when they host the banged-up Tennessee Titans as 6.5-point favorites. The Titans had their six-game winning streak snapped last week with a loss to the Texans, while injuries to skilled positions are stacking up. 

Can the Titans’ offense find an identity without Derrick Henry, Julio Jones, and possibly A.J. Brown, or will the Patriots continue to be successful with a great running game that compliments a No. 5 defense by success rate? Is this a perfect overreaction game?

Find out in our free NFL picks and predictions between the Titans and Patriots.

Titans vs Patriots odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

New England opened as a 2.5-point favorite on the look-ahead but opened up at -5.5 after Week 11 and that's been bet to -6.5. The total fell 2.5 points after it was available at 46.5 on the look-ahead and currently sits at 44.

Use the live odds widget above to track any future line movements right up until kickoff and be sure to check out the full NFL odds before placing your bets.

Titans vs Patriots predictions

Predictions made on 11/24/2021 at 4:30 p.m. ET.
Click on each prediction to jump to the full analysis.

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Titans vs Patriots game info

Location: Gillette Stadium, Foxborough, MA
Date: Sunday, November 28, 2021
Time: 1:00 p.m. ET

Titans at Patriots betting preview


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Key injuries

Titans: Olasunkanmi Adeniyi LB (Questionable), Jayon Brown LB  (Questionable), Greg Mabin CB  (Questionable), Elijah Molden CB  (Questionable), Geoff Swaim TE  (Questionable), AJ Brown WR (Out), Nate Davis G (Out), Rashaan Evans LB (Out), David Long LB (Out), Jeremy McNichols RB (Out), Teair Tart DT (Out), Derrick Henry RB (Out), Julio Jones WR (Out).
Patriots: Jake Bailey P  (Questionable), Christian Barmore DT  (Questionable), Ja'Whaun Bentley LB  (Questionable), Trent Brown T (Questionable), Nick Folk K  (Questionable), Damien Harris RB  (Questionable), Rhamondre Stevenson  (Questionable), Hunter Henry TE  (Questionable), Jonnu Smith  (Questionable), Dont'a Hightower LB  (Questionable). 
Find our latest NFL injury reports.

Betting trend to know

The Under is 4-0 in the Patriots’ last four home games vs. a team with a winning road record. Find more NFL betting trends for Titans vs. Patriots.

Titans vs Patriots picks and predictions

Our predictions are compiled from the analysis of the spread and total and are indications of where we are leaning for this game.
Our best bet is the play that we like the most for this game, which we would actually put some of our bankroll behind.

The New England hype train is running wild heading into Week 12. Bill and the boys have ripped off five straight wins and covered in each of them. Not only are the Pats 5-0 ATS in those games but the wins have come by an average of 21.7 points. That is nearly five straight, no-sweat wins, but is the proverbial bubble about to pop for the Pats with the Bills on deck for next week? We’re not so sure.

The Titans are absolutely decimated at skilled positions and could be down their top two running backs, top two wide receivers, and starting tight end heading into a matchup against a New England defense that has allowed just 50 points over its last five games. Bill Belichick’s defense is going to make life miserable for the Titans' offense, which comes into this meeting already struggling at 4.5 yards per play over its last three. Beating this New England Patriots defense that ranks No. 4 in success rate with replacement-level players at Gillette Stadium is a tall task. New England could score 20 points and still cover in this spot.

Also in New England’s favor is the turnover battle. Ryan Tannehill has thrown exactly one touchdown per game in his last three but has totaled five interceptions and has three fumbles (zero lost). Tennessee as a team has turned the ball over six times in its last three and could struggle with possession, as the Pats are averaging 2.7 takeaways since Week 9 and rank sixth in QB pressure rate at 26.6 percent. They face a Titans O-line that has allowed the fifth-most sacks this year.

We’re already leaning on the Pats at -6.5 and haven’t even mentioned the offense. There isn’t anything flashy about it, though. Mac Jones makes smarts passes and has just two picks over his last five games. Multiple running backs have come in and out of this lineup and found success for a running game behind a top-tier O-line. The Pats also just got their lead runner back last week in Damien Harris. The Titans' defense is an average unit but might be facing some short fields with their offense projecting to struggle with a team total of 17.5 points.

With an offense that will feature receivers Nick Westbrook-Ikhine and Chester Rodgers and running backs D’Onta Foreman and Dontrell Hilliard, we aren’t backing this Titans team even with 6.5 free points. This line might seem high, but New England was a 7-point road favorite last week in Atlanta while the Titans couldn’t even win straight up as home favorites against the Saints and Texans — two of the worst offenses in football. 

Prediction: Patriots -6.5 (-110)

This total was 46.5 on the look-ahead and has fallen to the key number of 44. Combined both teams are an even 11-11 O/U on the season and it will be tough for this game to pass through 44.

Offensively, Jones and the Pats are averaging a healthy 31.3 points per game, which came against the Falcons, Browns and Panthers — two teams in the top-seven in success rate. However, the Pats’ offense sits 14th in yards per game over that stretch and has benefited from a terrific defense that has been giving them short fields from turnovers (seven in the last three games) while holding opponents to an incredible 18 percent third down conversion rate. That’s right, the Patriots’ defense is holding opponents to 18 percent on third downs over the last three weeks and with a weak-looking Titans offense, we aren’t seeing this trend changing.

Tannehill and the Tennessee offense are converting third downs over the last three games at a 33 percent rate and possibly without Jones, Brown, and Geoff Swaim, this number could get worse before it gets better. 

We’d feel more comfortable with taking the Pats’ team total Over (26.5) instead of the game total. Any gains on the Tennessee offense could easily be erased by a Tannehill sack as he has been taken down more than any other QB in the league. 

The Titans’ defense shouldn’t be short-changed either, as they sit in the middle of the league in points and yards per game and rush and pass EPA. They are strong at all three levels, and Jeffrey Simmons and Harold Landry have combined for 17.5 sacks this season. 

Big plays won’t be on the agenda, either, Sunday. New England sits in the Top 10 in explosive pass plays and rush plays against while the Titans’ defense has allowed the second-fewest rushes of 10-plus yards, while their offense sits second-last in explosive pass plays.

The total is more of a lean than a play for us, as there just aren’t enough playmakers on either offense to push this needle to the Over.

Prediction: Under 44 (-110)

Tannehill, Foreman (who is questionable), Hilliard, Westbrook-Ikhine, Chester Rogers, and Anthony Firkser. That’s what Tennessee is working with on Sunday against an elite defense, with confidence, that can get pressure and cause turnovers. 

There are so many scenarios where we can see this nameless Tennessee offense go backward and give a short field to Jones and the offense. If Tannehill is forced to play catch-up, things could get really ugly, because this New England defense is relentless and doesn’t give up big plays. 

New England is averaging 10 points allowed per game over its last five games, dating back to October 24. The combination of Cleveland, Atlanta, and Carolina scored a total of one TD versus New England over the last three weeks, while Tennessee has managed under 300 yards of offense per game since Week 9.

The Titans’ team total is as low as 17.5 and as high as 19.5. There isn’t a huge difference in those numbers but we’re hitting the Under 19.5 at -117.

Pick: Titans team total Under 19.5 (-115)

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