Nothing hits harder than mid-week, mid-major college football as Jacksonville St. hosts FIU on Tuesday evening. Both teams are looking to keep their winning streaks alive.
Join me as I break down my FIU vs. Jacksonville St. predictions, including why the Panthers have caught my eye as underdogs this week. Kickoff is set for 8 p.m. ET on ESPNU.
Be sure to check out all of our college football picks for Week 7.
TOP PICK
Who will win FIU vs Jacksonville St.: FIU +2.5
Jacksonville State has been cruising down Easy Street, with its last five games coming against some pretty underwhelming rush defenses.
The Gamecocks love to lean on their ground game, with only 46% of their plays coming via the pass. So far this season, they are averaging 34.2 rushing attempts per game.
In Jacksonville State's last four games, no opponent has ranked higher than 77th in rushing yards allowed. Now, the Gamecocks draw a defense ranked seventh nationally in rushing yards allowed per game.
The best rush defense they have faced this season was in their opener against North Dakota State, which ranks 43rd nationally. The Gamecocks were held to just 85 rushing yards in that matchup.
FIU has allowed just under 82 rushing yards per game this season while holding opponents to 14.5 points per game, ninth nationally.
With such a low total in this matchup, defenses should shine, keeping points and yards at a premium. Give me the dog!
Dig for +3, but always take any points you can get in a college football game.

FIU vs Jacksonville St. Over/Under pick: Under 43.5
Like FIU's run defense, Jacksonville State's pass defense is very strong. The Gamecocks are limiting opposing teams to just 191.4 passing yards per game, ranking 36th nationally.
The Panthers rank 11th nationally in passing attempts per game and 25th in passing yards per game, averaging nearly 270 passing yards per contest. FIU is only averaging 18.5 points per game, so if the Gamecocks are able to hold down the Panthers' air attack, it's going to be hard for them to move the ball up and down the field.
FIU vs Jacksonville St. combo
If you combo all three plays above, you're looking at a 3.81x payout, which is solid value for a game that should feature minimal scoring and a rambunctious road dog looking to cause some havoc in Jacksonville, Ala.
FIU vs Jacksonville St. combo
- FIU +2.5
- Under 43.5
- 1H Under 23.5
- 2026 Season: 42-35-2, +7.40 units
FIU vs Jacksonville St. odds
For help understanding probabilities, see our odds calculator.
- Spread: FIU +2.5 | Jacksonville St. -2.5
- Over/Under: Over 43.5 (52%) | Under 43.5 (48%)
- Moneyline: FIU 43% | Jacksonville St. 57%
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FIU vs Jacksonville St. weather
Tuesday evening should bring perfect football weather in Jacksonville, Alabama, with temperatures in the upper 60s and a light breeze expected throughout the game.
Check out our college football weather page for up-to-date info on every matchup.
FIU vs Jacksonville St. trend to know
FIU is 4-1 to the Under this season. Find more college football betting trends for FIU vs. Jacksonville St.
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How to watch FIU vs Jacksonville St.
| Location | AmFirst Stadium, Jacksonville, Ala. |
| Date | Tuesday, Oct. 13, 2026 |
| Kickoff | 8 p.m. ET |
| TV | ESPNU |
FIU vs Jacksonville St. latest injuries
Check out our college football injuries page for updates on every team.
Odds are correct at the time of publishing and are subject to change.
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