Saint Francis vs TCU Prediction, Picks & Odds for Tonight's College Basketball Game

TCU will shake off a head-scratching season-opening loss with a blowout of Saint Francis, as our college basketball betting picks explain.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Nov 6, 2025 • 12:08 ET • 4 min read

NCAAB

Match starts: 3 hrs
TCU
65 %
SFPA
35 %
Read Analysis
TCU Horned Frogs NCAAM David Punch
Photo By - Imagn Images. TCU Horned Frogs forward David Punch (15) controls the ball.

The Saint Francis Red Flash head to Fort Worth to face the TCU Horned Frogs in college basketball action on Thursday night.

The Horned Frogs are coming off an embarrassing loss in their season opener. but my Saint Francis vs. TCU predictions expect them to pick up a huge win tonight. Here are my best free college basketball picks for this clash on November 6. 

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Saint Francis vs TCU prediction

Saint Francis vs TCU best bet: TCU -27.5 (-110)

The Saint Francis Red Flash hung tough with Oklahoma in the first half of their season opener. However, the Sooners went on a 35-3 run early in the second half and ended up winning by a final score of 102-66.

Meanwhile, the TCU Horned Frogs are coming off a 78-74 loss to New Orleans despite entering as 21-home point home faves. While losing to a school that finished with a 2-18 record in the Southland Conference last year is a bad sign, there are a few reasons TCU can bounce back with a big win tonight. 

The Horned Frogs went a horrific 3-for-27 from deep against New Orleans. Positive regression should set in. More importantly, TCU will likely focus on attacking the rim, which is an area where Saint Francis can be exploited.

The Frankies allowed the Sooners to shoot 70% from 2-point range and score 54 points in the paint. Expect TCU to feed the ball inside to forwards David Punch and Xavier Edmonds, who will do damage. 

It's also worth noting that TCU was outrebounded 39-28 by the Privateers, who have great size in their frontcourt. The Frogs won't be controlled on the glass by a much smaller Saint Francis squad that has a 6-foot-9 center and no other rotation player taller than 6-foot-6.

Jamie Dixon's squad always does a good job of pressuring ball handlers and forced 19 turnovers versus New Orleans. The Frankies turned the ball over 14 times against OU, which led to 22 points the other way. 

This is SFU's last year in Division I before moving to Division III. The Frankies have a completely rebuilt roster under a new head coach, and there will be plenty of blowout losses this season. This will be one of them. 

Saint Francis vs TCU same-game parlay

The Horned Frogs pushed the pace on Tuesday, and I expect their offense to be far more efficient tonight. Combine that with a Frankies squad that has cased the Over in 20 of their last 29 games, and I'm playing the Over in this SGP.

Saint Francis vs TCU SGP

  • TCU -27.5
  • Over 150.5

Saint Francis vs TCU odds

  • Spread: Saint Francis +27.5 | TCU -27.5
  • Moneyline: OTB
  • Over/Under: Over 150.5 | Under 150.5

Saint Francis vs TCU betting trend to know

The Over is 20-9 in the last 29 games for Saint Francis (+10.10 Units / 32% ROI). Find more NCAA betting trends for Saint Francis vs. TCU.

How to watch Saint Francis vs TCU

Location Ed and Rae Schollmaier Arena, Fort Worth, TX
Date Thursday, November 6, 2025
Tip-off 8:00 p.m. ET
TV TNT, truTV

Saint Francis vs TCU key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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