Minnesota vs Purdue Prediction, Picks & Odds for Tonight's College Basketball Game

Purdue is looking to flush a forgettable performance, and protecting home court against Minnesota is the perfect chance to do it.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Dec 10, 2025 • 10:59 ET • 4 min read

NCAAB

Match starts: 6 hrs
PUR
61 %
MINN
39 %
EXPERT PICK - SPREAD
Purdue -20.0 (-115) Purdue -20.0 (-115)
Read Analysis
Fletcher Loyer Purdue Boilermakers NCAAB
Photo By - Imagn Images. urdue Boilermakers guard Fletcher Loyer (2) smiles after a made basket in the second half.

The No. 6 ranked Purdue Boilermakers try to bounce back from an ugly loss as they host the Minnesota Golden Gophers on Wednesday night.

Early money has come in on the Boilermakers who are now installed as 20-point favorites and my Minnesota vs. Purdue predictions are laying the points with the home side. 

Here are my best free college basketball picks for this Big Ten clash on December 10.

Minnesota vs Purdue prediction

Minnesota vs Purdue best bet: Purdue -20 (-110)

The Minnesota Golden Gophers are fresh off an upset win against Indiana last week. However, that snapped a three-game skid for the Gophers who have lost by double digits to Missouri, San Francisco, and Santa Clara. 

The Purdue Boilermakers are coming off a humiliating 23-point loss at home against Iowa State last Saturday. Prior to that defeat, they were the No. 1 ranked team in the country and had gone 8-0 with wins against No. 12 Alabama and No. 16 Texas Tech. 

The Boilermakers lost to the No. 4 Cyclones because their usually efficient offense had an off night. They came into that contest shooting 41.8% from deep and 77.3% from the line, while averaging 9.5 turnovers per game.

However, they went just 4-18 from the arc and 6-14 from the charity stripe with 15 turnovers against ISU's elite defense. They'll have a much easier time against Minnesota who is 212th in the country in opponent turnover rate and outside the Top 300 in 3-point defense (37.2%).

The Gophers offense has been heavily reliant on getting to the line, leading the country in free throw line. However, Purdue does an excellent job of defending without fouling, ranking second in opponent FT rate.  

With Minnesota struggling to get calls on the road and a highly-motivated Purdue squad going ballistic from long range, back the Boilermakers to win big here. 

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Minnesota vs Purdue same-game parlay

If the Boilermakers want to cover this massive spread they'll need to have success from beyond the arc. That means plenty of treys from their best shooter in Fletcher Loyer who is knocking down 3.0 triples per game at a 46.6% clip.

This leg of the SGP pays out at +130 and pairs nicely with the Over 1.5 assists for Oscar Cluff who has eclipsed this number in six of nine games. The center does a good job of kicking the ball out to open perimeter players when he gets the ball inside.

Minnesota vs Purdue SGP

  • Purdue -20
  • Fletcher Loyer Over 2.5 threes
  • Oscar Cluff Over 1.5 assists

Our beyond the arc SGP: Tyson to flourish

Even if Purdue wins in a blowout fashion we should see solid numbers for Cade Tyson who leads Minnesota with 21.8 ppg on 53/37/81 shooting splits.

Tyson has played 157 of 160 minutes over the last four games and will carry the scoring load on a team that lacks offensive threats.

Minnesota vs Purdue SGP

  • Purdue -20
  • Fletcher Loyer Over 2.5 threes
  • Oscar Cluff Over 1.5 assists
  • Cade Tyson Over 18.5 points

Minnesota vs Purdue odds

  • Spread: Minnesota +20 | Purdue -20
  • Moneyline: Minnesota +1550 | Purdue -4000
  • Over/Under: Over 143 | Under 143

Minnesota vs Purdue betting trend to know

The Golden Gophers are 1-6 ATS in their last seven games. Find more college basketball betting trends for Minnesota vs. Purdue.

How to watch Minnesota vs Purdue

Location Mackey Arena, West Lafayette, IN
Date Wednesday, December 10, 2025
Tip-off 7:00 p.m. ET
TV BTN

Minnesota vs Purdue key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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