College Basketball Best Bets Today: Top Picks From Every Game Preview

Aisha Quiñones - Betting Analyst at Covers
Aisha Quiñones • Betting Analyst 12+ years betting experience
Updated: Nov 10, 2026 , 04:30 PM ET • 4 min read

Our experts dive into the top games from a busy opening night in college hoops.

Marcis Ponder Florida State Seminoles Patrick Ngongba II Duke Blue Devils Tre White Kansas Jayhawks NCAAB
Photo By - Reuters Connect. Marcis Ponder Florida State Seminoles Patrick Ngongba II Duke Blue Devils Tre White Kansas Jayhawks NCAAB

Tuesday features a packed college basketball slate, headlined by a Sunshine State clash as Florida visits Florida State before a Champions Classic marquee battle between Michigan State and Duke at the United Center.

Our college basketball predictions highlight the featured picks from Covers analysts across the slate.

See more expert betting angles in our free college basketball picks for Nov. 10.

College basketball top picks at a glance (Tuesday, Nov. 10)

Matchup & time Top pick & analyst
Florida vs. Florida State
6 p.m. ET
Florida State +9.5
Geoff Clark
Michigan State vs. Duke
7 p.m. ET
Duke -7.5
Chris Hatfield
Kansas vs. Kentucky
9:30 p.m. ET
Kansas -4.5
Colby Marchio

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Florida vs. Florida State pick: Florida State +9.5

Top pick: Florida State +9.5

Unlike most teams, the Florida State Seminoles have enough size to handle the Florida Gators' frontcourt.

According to KenPom, the Seminoles have a taller average height with four starters who measure 6-foot-7 or taller. This includes 7-foot center Marcis Ponder and 6-foot-11 stretch four Sebastian Rancik. 

Also, this is an annual meeting between these in-state rivals, and FSU covered as a 17.5-point road underdog in a 78-76 loss last season in Gainesville.

Granted, Florida is better this year, but last season was Seminoles head coach Luke Loucks' first in Tallahassee. On3.com ranks FSU's transfer class seventh nationally and its recruiting class No. 16.

Read Geoff Clark's full Florida vs. Florida State prediction for more picks.

Michigan State vs. Duke pick: Duke -7.5

Top pick: Duke -7.5

Patrick Ngongba II has looked like a lottery pick against lowly competition, quite literally exceeding the production that Cameron Boozer gave Duke against similar competition a season ago. Michigan State won't have an answer for him.

Cayden Boozer can find him on cuts and seals before the Michigan State Spartans get their half-court defense organized, and John Blackwell gives Duke another guard who can punish help.

The Spartans have size in Anton Bonke, but replacing Carson Cooper and Jaxon Kohler leaves Izzo an early choice: stay mobile with Coen Carr alongside Bonke, or use a bigger lineup that Duke can make defend in space. Neither is a great choice, and a genuine question arises whether Sparty has enough athleticism if they choose the former. That matters more than Izzo's strong record against them.

Fears is good enough to slow the game and challenge the number, but Chris Hatfield expects Duke to create the cleaner shots and win by multiple possessions.

Read Chris Hatfield's full Michigan State vs. Duke prediction for more picks.

Kansas vs. Kentucky pick: Kansas -4.5

Top pick: Kansas -4.5

It was speculated that longtime Jayhawks head coach Bill Self debated retirement this offseason, but he ultimately decided to return. That goes to show how much he believes in this team and its ceiling. Self might be feeling like it's 2022 all over again. We've seen just how good the Jayhawks can be early on this season, with Kansas destroying Fordham and Middle Tennessee in its first two games.

On the other side, Kentucky is a mess. Mark Pope's seat gets a little warmer with every close win against teams ranked more than 100 spots below the Wildcats. Kentucky has lost its mojo since spending $22 million on its roster a year ago.

The Wildcats are unbettable until they can prove otherwise. This is a very talented Kansas team, and even as a road favorite, the Jayhawks should be able to tally a two-possession win.

Read Colby Marchio's full Kansas vs. Kentucky prediction for more picks.

More college basketball picks

Want to build a bigger card? These Covers roundups cover more bet types for today's games:

Check the college basketball injury report before finalizing today's picks.

All of today's matchups are also on the college basketball scores and matchups page, and the full pick archive lives in free college basketball picks.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Aisha Quiñones - Covers
Betting Analyst

Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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