The Memphis Grizzlies are putting the pieces back together, winning six of their last eight, but, in a small sign of maturation, the Minnesota Timberwolves have fared well when favored.
My Grizzlies vs. Timberwolves predictions will trust one of the home team's maturing pieces, Jaden McDaniels.
I dig in deeper with my NBA picks ahead of the 8 p.m. ET tip on Wednesday, December 17.
Grizzlies vs Timberwolves prediction
Grizzlies vs Timberwolves best bet: Jaden McDaniels Over 14.5 Points (-125)
With or without Anthony Edwards in the Minnesota Timberwolves lineup — and there is reason to expect Edwards to miss his third straight game with foot soreness — believe in Jaden McDaniels’ offensive development.
The sixth-year wing has cleared this prop in four of his last six games and in 13 of 25 this season.
Go ahead, be skeptical.
Then realize McDaniels’ current average of 15.8 points per game is a full 3.6 points higher than his career best; his 41.8% shooting from deep is leaps and bounds better than his 33.7% two years ago and 33.0% last season; and McDaniels’ 11.9 shots per game is 1.7 more than the career high set last year and 3.2 above than just two seasons ago.
Even if focusing on McDaniels’ 19 games with Edwards in the lineup — but Edwards not being “active” in Tuesday’s practice, per Timberwolves head coach Chris Finch, bodes poorly for his Wednesday availability — McDaniels would be setting career highs in points (14.0 vs. 12.2), 3-point shooting (41.8% vs. 39.8% three years ago) and shot attempts (10.9 vs. 10.2).
This is who he is now. With or without Edwards, Minnesota has proven itself right in believing McDaniels would eventually become a multi-level scorer.
Without Edwards, it should be noted that McDaniels has averaged 21.5 points in six games this year, clearing this prop in five of the six.
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Grizzlies vs Timberwolves same-game parlay
Naz Reid has always been a scorer, but he is still undervalued in that regard. Reid has cleared this prop in 14 of 26 games this season, including five of six without Edwards in the lineup, averaging 16.7 points in those six games.
Edwards is officially listed as questionable. The best way to exploit that uncertainty is to target thoughts that could cash with him in the lineup but have a greater likelihood without him. If Edwards plays, both McDaniels and Reid can still pour it in.
That happens plenty. If Edwards sits, then this same-game parlay could come down to Minnesota winning its second home game this week.
Grizzlies vs Timberwolves SGP
- Jaden McDaniels Over 14.5 points
- Naz Reid Over 14.5 points
- Timberwolves moneyline
Our "from downtown" SGP: Contingency planning
Both McDaniels and Reid spend less time in the paint when Edwards is out, thus grabbing fewer rebounds. McDaniels has averaged 4.8 rebounds this season alongside Edwards, but just 4.3 without him. Reid, meanwhile, has averaged 6.3 rebounds this season alongside Edwards but just 5.5 without him.
There is value to be found here even if Edwards plays, but it escalates if he does indeed miss a third straight game.
Grizzlies vs Timberwolves SGP
- Jaden McDaniels Over 14.5 Points
- Naz Reid Over 14.5 Points
- Timberwolves moneyline
- Jaden McDaniels Under 4.5 Rebounds
- Naz Reid Under 6.5 Rebounds
Grizzlies vs Timberwolves odds
- Spread: Grizzlies +7.5 | Timberwolves -7.5
- Moneyline: Grizzlies +240 | Timberwolves -300
- Over/Under: Over 232.5 | Under 232.5
Grizzlies vs Timberwolves betting trend to know
Minnesota is 16-5 outright this season when favored. Find more NBA betting trends for Grizzlies vs. Timberwolves.
How to watch Grizzlies vs Timberwolves
| Location | Target Center, Minneapolis, MN |
| Date | Wednesday, December 17, 2025 |
| Tip-off | 8:00 p.m. ET |
| TV | FDSN Southeast-Memphis, FDSN North |
Grizzlies vs Timberwolves latest injuries
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