It’s another busy day across the big leagues, with 15 games on the schedule. My MLB player props analysis will include Nico Hoerner, Munetaka Murakami, and Shohei Ohtani.
Read more in my MLB picks for Wednesday, April 22.
Best MLB player props today
| Player | Pick | Odds |
|---|---|---|
 Nico Hoerner |
Over 0.5 RBI | +180 |
 Munetaka Murakami |
Over 0.5 RBI | +150 |
 Shohei Ohtani |
Over 6.5 strikeouts | -122 |
Nico Hoerner Over 0.5 RBI (+180)
Nico Hoerner has been red-hot lately. The Chicago Cubs infielder is batting .326 overall and .347 in the month of April. He’s logged an RBI in three of his last five contests, driving in four during that span.
In fact, Hoerner is currently tied for third in the league in that category, registering 22 RBI already.
He’ll face Kyle Backhus tonight after going 2-for-5 with a home run and an RBI last night.
- Time: 7:40 p.m. ET
- Where to watch: Marquee, NBCS-Philadelphia
Munetaka Murakami Over 0.5 RBI (+150)
Hoerner may be hot, but I don’t believe anyone is swinging the bat like Munetaka Murakami is right now. The slugger has eight RBI across his last four games, and he’s also gone deep in four straight appearances. He can't be stopped.
He was 3-for-5 in Tuesday’s series opener against the Arizona Diamondbacks with a home run, an RBI, and three hits. Murakami has six of his 17 RBI against lefties, and Eduardo Rodriguez takes the hill tonight for Arizona.
- Time: 9:40 p.m. ET
- Where to watch: CHSN, Dbacks.TV
Shohei Ohtani Over 6.5 strikeouts (-122)
Shohei Ohtani takes the hill tonight against the San Francisco Giants, whom he’s dominated in the past.
They’re hitting just .176 against him, and he’s struck out 18 in 51 at-bats. It’s common knowledge that Ohtani has overpowering stuff, and he racked up 10 Ks in his last start against the Mets.
While San Fran is around the middle of the pack in team strikeouts, they’re swinging and missing a lot more lately, striking out nearly 10 times per game across their previous three contests. Also, Ohtani has collected 16 Ks in 12 innings of work at Dodger Stadium in 2026.
- Time: 9:45 p.m. ET
- Where to watch: SportsNet-Los Angeles, NBCS-Bay Area
- Prop picks: 3-6, -1.78 units
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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