The Seattle Mariners and Minnesota Twins continue their four-game series tonight at Target Field in Minneapolis.
George Kirby is finding his form, and my Mariners vs Twins predictions and MLB picks for Wednesday, June 25, focus on his ability to keep Minnesota at bay.
Mariners vs Twins prediction
My Mariners vs Twins best bet: George Kirby Under 2.5 earned runs allowed (-145 at bet365)
⚾ Pick Analysis
The Seattle Mariners’ pitching staff hasn’t been the most consistent this season. Seattle was hoping George Kirby could make a difference when he returned from injury. Unfortunately, he’s struggled in six starts, posting a 6.16 ERA, with opponents hitting .292 off the right-hander.
However, Kirby is starting to regain his composure, which is a very good sign for the M’s. He’s allowed Under 2.5 earned runs in three of his last four outings. While Kirby did surrender four earned runs against the Chicago Cubs last Friday, he still kept his team in the game, lasting five innings.
Before that, Kirby had three consecutive quality starts. We even saw a dominant performance from the 27-year-old on June 8, striking out 14 across seven innings of two-run baseball versus the Los Angeles Angels.
Kirby is a very good starter at the big league level — it’s just taken him some time to get his feet under him this year.
I expect him to limit the damage against the Minnesota Twins tonight, too. Minnesota has lost five straight and 11 of 12.
Mariners vs Twins same-game parlay (SGP)
🚀 SGP Analysis
Matt Wallner is 3-for-5 lifetime versus the right-hander with a home run and two RBIs.
Wallner has cashed the Over in hits in five of his last six contests as well. He does hit a mile better at home, batting .250 compared to .159 on the road. He’ll keep it rolling this evening and collect one hit, at the very least, against Kirby or the Mariners bullpen.
The Twins' Joe Ryan is 7-3 with a 3.06 ERA in 15 outings, striking out 96 in 85 1/3 innings. That will be my focus here. Ryan misses a lot of bats, cashing the Over in Ks in back-to-back starts.
Ryan had seven punchouts last time out against the Brewers and collected another seven before that vs. the Astros. He’s racked up 49 Ks in 38 1/3 frames at home and has struck out 14 in 40 at-bats against this Mariners lineup.
Mariners vs Twins odds
Mariners vs Twins live odds
Mariners vs Twins opening odds
- Moneyline: Seattle +110 | Minnesota -130
- Run line: Seattle +1.5 (-180) | Minnesota -1.5 (+150)
- Over/Under: Over 8 (+100) | Under 8 (-120)
Mariners vs Twins trend
The Minnesota Twins have hit the Game Total Over in 19 of their last 32 games (+6.05 Units / 17% ROI). Find more MLB betting trends for Mariners vs. Twins.
How to watch Mariners vs Twins and game info
Location | Target Field, Minneapolis, MN |
Date | Wednesday, 6-25-2025 |
First pitch | 7:40 p.m. ET |
TV | RSNW, TWINS.tv |
Mariners starting pitcher | George Kirby (1-3, 6.16 ERA) |
Twins starting pitcher | Joe Ryan (7-3, 3.06 ERA) |
Mariners vs Twins latest injuries
Mariners vs Twins weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.